小针刀加拔罐治疗冈下肌损伤23例

冈下肌损伤在临床较为常见，近两年来，笔者采用小针刀加拔罐治疗，取得了满意的疗效，现总结如下。     

颅脑创伤所致线粒体损伤和功能障碍

在颅脑损伤早期即可观察到代谢障碍和功能损伤,并可持续数天。伤后的一系列改变包括:代谢底物耗尽,大量活性氧生成,钙离子超载,蛋白质和DNA氧化损伤等,使细胞逐渐走向凋亡或坏死。因此,深入地了解颅脑损伤后线粒体变化,以线粒体为靶目标进行干预,可能会显著地减少细胞损伤。     

单侧骨窗开颅法治疗非对称性双侧额叶脑挫裂伤14例

颅脑损伤中双侧额叶挫裂伤虽然发生率较低,但对冲性双侧额叶脑挫裂伤是闭合性颅脑损伤中一种严重脑损伤。非对称性双侧额叶脑挫裂伤是其中一种特殊类型。我科自1995年1月至2005年5月选择性地对非对称性双侧额叶脑挫裂伤进行单侧骨窗开颅治疗14例,现报告如下。1对象与方法1·1临     

急性一氧化碳中毒对肺部损伤的临床观察

急性一氧化碳中毒脑组织受累最常见。但有一部分患者常常出现肺部受累．尤其是昏迷的患者．常因肺部损伤未能及早诊断而影响治疗效果。现将我院2003年至2005年一氧化碳中毒患者出现肺部损伤的X线诊断和临床治疗结果总结如下。     

还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

腰骶脊髓损伤患者肛管直肠功能障碍的研究

目的研究腰骶脊髓损伤患者肛管直肠功能状况。方法以115例腰骶脊髓损伤患者为脊髓损伤组,以22例尿道下裂和血尿患者为对照组,检测两组的肛管直肠功能。结果脊髓损伤组最大肛管收缩压为(56.7±31.1)mmHg(1mmHg=0.133kPa),对照组为(87.2±29.2)mmHg,两组比较,差异有统计学意义(P<0.01);在行咳嗽动作时,脊髓损伤组31例(27.0%)肛管压力瞬时升高,但之后出现大幅度、持续性下降;在行模拟排便动作时,97例(84.3%)表现为盆底功能紊乱型肛管直肠压力曲线。直肠肛管抑制反射在所有受检者均存在,脊髓损伤组诱发持续性直肠肛管抑制反射所需直肠气囊容量和直肠感觉阈值分别为(134.8±48.5)ml和(95.9±54.3)ml,对照组分别为(55.9±17.9)ml和(42.3±13.1)ml,两组比较,差异均有统计学意义(P<0.01)。结论多数腰骶脊髓损伤患者不能自主收缩肛门外括约肌,直肠感觉功能受到严重损害;部分腰骶脊髓损伤患者咳嗽肛管反射通路可能受到损害;直肠肛管抑制反射可能受到中枢神经系统的调控。