1例卵巢幼年型颗粒细胞瘤患儿的护理

卵巢幼年型颗粒细胞瘤(JGCT)是一种罕见的性索间质肿瘤,占卵巢颗粒细胞瘤的5%[1-2],2007年1月我科收治1例卵巢幼年型颗粒细胞瘤的患儿,接受手术 化学药物治疗,预后良好。现将护理体会介绍如下。1病例介绍患儿,女性,1岁6个月,因白带增多,阴道持续点滴出血2周,诊断为左卵巢幼年型     

单腔起搏复律除颤器反复放电1例分析

患者女性，46岁，既往有甲亢病史5年，阵发性房颤间歇服用胺碘酮一年。于2002年8月19日因精神悲伤，突然意识丧失，晕倒在地，口唇发绀小便失禁，5min后送入我院急救中心，心电图示：尖端扭转型室速室颤，前、后反复电除颤10次，恢复窦性心律，频发房早，间歇短阵房颤，T波倒置，Q—T间期440-480ms，为防止再次室颤，于2002年9月7日安置单腔起博复律除颤器(ICD)，     

非程序性冷冻仪冻存人胚胎干细胞的方法

在人胚胎干细胞（human embryonic stem，hES）的研究中，有效的冻存方法非常重要。目前，冷冻Es细胞主要有两种方法：慢速冷冻一快速复温和超快速玻璃化法。慢冻法需要昂贵的程序性冷冻仪，而玻璃化法步骤繁琐且只能冻存小量细胞．不能满足临床应用。因此，本研究旨在寻找非程序性冷冻仪冻存大量hES细胞的方法。     

兔肢体爆炸伤合并海水浸泡后在不同复温速率及维持浅低体温下机体炎症反应的特征

Objective To investigate effects of different rewarming rates and maintenance of light hypothermia on inflammatory response in rabbits after limb blast injury, coupled with seawater immersion. Methods First, the model of limb blast injury coupled with seawater immersion was reproduced [the animals were immersed to low body temperature of (31.0±0.5℃)]. Then, 24 adult rabbits were randomly divided into group Ⅰ [the rapid rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (8.94±0.93)℃/h], group Ⅱ [the slow rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (3.88±0.22)℃/h], group Ⅲ [another slow rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (2.18±0.12)℃/h], and the H group [the hypothermia group, n =6, rewarmed to (34 - 35)℃ at a rate of (4.49±0.66)℃/h and kept at that temperature till termination of the experiment]. Regulation of ambient temperature and warm transfusion were used to restore body temperature to target levels and maintained there for 6 hours. Blood samples were taken at 5 different times, I.e. Pre-injury time(T0), post-immersion time (T1), the time when rewarming started (T2), 3 h after rewarming (T3), and 6 h after rewarming (T4). Tissue samples from heart, liver, intestinum, lung and kidney were also collected. Levels of TNF-α (tumor necrosis factor-α), IL-1β (interleukin-1β) and IL-6 (interleukin-6) in plasma and MPO (myeloperoxidase) in homogenate were detected. Results Following rewarming, TNF-α, IL-1β, IL-6 concentrations in the plasma of the animals in group Ⅰ and group H were significantly higher when compared with those of the animals in group Ⅱ and group Ⅲ (P<0.05, P<0.01), and MPO activity in homogenate was significantly higher when compared with that of the animals in group Ⅱ and group Ⅲ(P<0.01, P<0.05), and no statistical difference could be seen between group Ⅱ and Ⅲ (P>0.05). Conclusions Rapid rewarming and maintenance of light hypothermia could obviously elevate TNF-α, IL-1β, IL-6 concentrations in plasma and MPO activity in homogenate, following limb blast injury coupled with hypothermia induced by seawater immersion, while slow rewarming (with a rewarming rate of 2-4℃/h) could significantly inhibit TNF-α, IL-1β, IL-6 levels and PMN activity.     

苓桂术甘汤的临床运用

苓桂术甘汤出自<伤寒论·辨太阳病脉证并治>:"伤寒若吐若下后,心下逆满,气上冲胸,起则头眩,脉沉紧,发汗则动经,身为振振摇者,茯苓桂枝白术甘草汤主之".<金匮要略·痰饮咳嗽病脉证并治>:"心下有痰饮,胸胁支满,目眩,苓桂术甘汤主之","夫短气有微饮,当从小便去之,苓桂术甘汤主之.肾气丸亦主之".     

脑功能状态指数(CSI)在全麻中作为镇痛深度监测的实验研究

目的研究应用靶控输注瑞芬太尼和丙泊酚时脑功能状态指数（CSI）是否可以作为镇痛深度监测的指标。方法选择50例腹腔镜下胆囊切除全麻手术患者。全麻诱导和维持使用丙泊酚、维库溴铵和瑞芬太尼。记录病人的基础血压、心率、血氧饱和度、CSI、BIS值变化,观察插管前后及切皮前后血压、心率、血氧饱和度、CSI、BIS值。结果气管插管前后和切皮刺激前后的心率、收缩压相比较有显著性差异;对于气管插管前后和切皮刺激前后的BIS、CSI值各自比较无显著性差异。结论 CSI不能用于患者术中镇痛深度即对伤害性刺激反应的监测。     

复方谷氨酰胺颗粒治疗复发性阿弗他溃疡

2008年3月-2009年3月我院采用复方谷氨酰胺颗粒（海南海神同洲制药有限公司生产，批号：20060504，规格：0．67g／袋）治疗复发性阿弗他溃疡29例，效果显著，报告如下。     

术前产前24 943例患者血清感染性指标的调查分析

近年来医务人员的职业感染和患者医院内感染都处于上升状态，并且随着艾滋病的流行呈上升趋势，这构成临床医务人员和非病毒感染患者的健康威胁。本研究对我院2007年1月至2008年12月就诊的术前、产前患者乙型肝炎病毒表面抗原（HBsAg）、抗丙型肝炎病毒抗体（抗HCV）、明胶颗粒凝集试验（TPPA）及抗人类免疫缺陷病毒（抗HIV1／2）的检测结果作回顾性统计分析。     

枳术颗粒合用奥美拉唑治疗消化性溃疡41例疗效观察

目的 观察枳术颗粒合用奥美拉唑对消化性溃疡的疗效.方法 治疗组41 例,患者口服奥美拉唑和枳术颗粒治疗消化性溃疡,与对照组36 例单纯口服奥美拉唑作对比分析.结果 治疗组1个疗程治愈38例(92.6%),服药2个疗程41例均治愈,半年未有复发病例;对照组1个疗程治愈26例(72.2%),服药2个疗程治愈32例,好转3例,无效1例,半年复发5例.两组疗效比较有显著性差异(P＜0.05).结论 枳术颗粒可健脾消食、行气化湿,与奥美拉唑合用治疗消化性溃疡,中西医结合,相得益彰,症状缓解快,复发率低,可提高临床疗效.