全文获取类型
收费全文 | 36606篇 |
免费 | 3481篇 |
国内免费 | 812篇 |
专业分类
耳鼻咽喉 | 1261篇 |
儿科学 | 884篇 |
妇产科学 | 325篇 |
基础医学 | 5179篇 |
口腔科学 | 916篇 |
临床医学 | 4286篇 |
内科学 | 5356篇 |
皮肤病学 | 183篇 |
神经病学 | 5021篇 |
特种医学 | 1677篇 |
外国民族医学 | 4篇 |
外科学 | 2367篇 |
综合类 | 4105篇 |
现状与发展 | 2篇 |
一般理论 | 2篇 |
预防医学 | 3087篇 |
眼科学 | 536篇 |
药学 | 3224篇 |
39篇 | |
中国医学 | 1359篇 |
肿瘤学 | 1086篇 |
出版年
2024年 | 135篇 |
2023年 | 755篇 |
2022年 | 1194篇 |
2021年 | 1910篇 |
2020年 | 1902篇 |
2019年 | 1615篇 |
2018年 | 1578篇 |
2017年 | 1643篇 |
2016年 | 1447篇 |
2015年 | 1414篇 |
2014年 | 2434篇 |
2013年 | 2473篇 |
2012年 | 2011篇 |
2011年 | 2100篇 |
2010年 | 1872篇 |
2009年 | 1753篇 |
2008年 | 1696篇 |
2007年 | 1598篇 |
2006年 | 1437篇 |
2005年 | 1157篇 |
2004年 | 1014篇 |
2003年 | 879篇 |
2002年 | 795篇 |
2001年 | 574篇 |
2000年 | 534篇 |
1999年 | 516篇 |
1998年 | 417篇 |
1997年 | 337篇 |
1996年 | 285篇 |
1995年 | 296篇 |
1994年 | 265篇 |
1993年 | 235篇 |
1992年 | 237篇 |
1991年 | 183篇 |
1990年 | 187篇 |
1989年 | 179篇 |
1988年 | 161篇 |
1987年 | 138篇 |
1986年 | 137篇 |
1985年 | 186篇 |
1984年 | 184篇 |
1983年 | 157篇 |
1982年 | 155篇 |
1981年 | 152篇 |
1980年 | 139篇 |
1979年 | 92篇 |
1978年 | 75篇 |
1977年 | 56篇 |
1976年 | 51篇 |
1975年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
101.
Contact dermatitis in patients with leg ulcers 总被引:3,自引:2,他引:1
100 patients with leg ulcers were patch tested against a standard battery of allergens. The readings were carried out daily from the 2nd to the 7th days. 55 patients showed positive reactions to one or more allergens. 32% of positive reactions developed for the first time after 48 h and 11% after 72 h. No single day or combination of two days gave 100% positive results. A single reading on the 4th day gave the highest number of positive reactions at 92%. The prevalence of positive patch tests was significantly higher in patients with surrounding eczema, and in patients with positive patch tests the ulcer duration was significantly longer than in those with negative patch tests. The total number of positive results in individuals increased linearly with the duration of the ulcer. Of allergens to which the ulcer was exposed, the occurrence of multiple sensitivity was significantly greater than predicted from the prevalence of individual sensitivities. However, there was no association between medicaments and metal sensitivity. This, together with the absence of an exponential rise in the number of allergens with the duration of ulcer, does not support the theory of systemic ampliative allergy. 相似文献
102.
应用修正正交分段线性函数的时滞和反向特性,推导出求解时滞系统和卷积的公式。数字仿真表明,它具有计算简单,精度高的优点。 相似文献
103.
J. F. Bergmann O. Chassany P. J. Guillausseau M. Bayle S. Chagnon C. Caulin J. R. Sallenave 《European journal of clinical pharmacology》1992,43(2):121-124
Summary The aim of the study was to use a novel combination of two methods for the simultaneous evaluation of two effects of oral cisapride in 10 diabetic patients with autonomic neuropathy; gastric emptying time was measured by following radio-opaque markers and orocaecal transit time by the sulphasalazine-sulphapridine method. The study was of double-blind, randomized, placebo-controlled, cross-over design.It was possible to evaluate the effect of a prokinetic drug on gastric emptying and orocaecal transit times using these two noninvasive techniques at the same time. Cisapride significantly reduced both the gastric emptying (1.2 h versus 2.1 h) and orocaecal tansit (5.9 h versus 7.7 h) times. 相似文献
104.
采用直接窦房传导时间(SACTd)为指标,对10例窦房结功能正常者进行了针刺前、针刺及固有心率(IHR0)期间SACTd测定,以探讨电针内关穴对窦房传导功能的影响及其意义。结果表明:电针与IHR0期间SACTd较对照期显著缩短(P〈0.01;P〈0.001)。自主神经阻滞后,电针该穴不能使SACTd进一步缩短(P〉0.05)。提示;以内关穴为主的电针刺激能改善正常窦房传导功能,其作用似与自主神经中 相似文献
105.
106.
Cell culture-based influenza vaccine manufacturing is of growing importance. Depending on virus strains, differences in infection dynamics, virus-induced apoptosis, cell lysis and virus yields are observed. Comparatively little is known concerning details of virus–host cell interaction on a cellular level and virus spreading in a population of cells in bioreactors. In this study, the infection of MDCK cells with different influenza A virus strains in lab-scale microcarrier culture was investigated by flow cytometry. Together with the infection status of cells, virus-induced apoptosis was monitored. A mathematical model has been formulated to describe changes in the concentration of uninfected and infected adherent cells, dynamics of virus particle release (infectious virions, hemagglutinin content), and the time course of the percentage composition of the cell population. 相似文献
107.
采用LabVIEW技术完成对心电、呼吸、无创血氧和无创血压信号的采集与处理,而后通过MATLAB模糊测量系统对采集的人体生理信号进行模糊预测分析。通过实验检验了人体生理信号检测、处理和模糊预测分析方法的可靠性。LabVIEW技术对人体生理信号的模糊预测分析是有效的,可用于检测阻塞性睡眠呼吸暂停患者的生理状态信号。 相似文献
108.
右归饮择时使用对肾阳虚大鼠生长激素昼夜节律的影响 总被引:1,自引:0,他引:1
目的 探讨右归饮择时用药在肾阳虚证治疗中的意义。 方法 采用放免法 ,以肾阳虚大鼠血清生长激素为指标 ,观察右归饮择时用药的疗效。结果 右归饮择时用药对肾阳虚大鼠症状的改善有一定作用 ,并以卯时用药效果较好。结论 右归饮治疗肾阳虚证应当提倡择时用药。 相似文献
109.
M J Rosenthal D Smith L Yaguez V Giampietro D Kerr E Bullmore M Brammer S C R Williams S A Amiel 《Diabetic medicine》2007,24(7):720-727
AIMS: Caffeine enhances counterregulatory responses to acute hypoglycaemia. Our aim was to explore its effects on cortical function, which are not known at present. METHODS: Regional brain activation during performance of the four-choice reaction time (4CRT) at different levels of complexity was measured using functional magnetic resonance imaging (fMRI) at euglycaemia (5 mmol/l) and hypoglycaemia (2.6 mmol/l) in the presence and absence of caffeine in six healthy right-handed men. RESULTS: During hypoglycaemia, caffeine enhanced adrenaline responses to hypoglycaemia (2.5 +/- 0.7 nmol/l to 4.0 +/- 1.0 nmol/l, P = 0.01) and restored the brain activation response to the non-cued 4CRT, the linear increases in regional brain activation associated with increased task complexity and the ability to respond to a cue that were lost in hypoglycaemia alone. CONCLUSIONS: Caffeine can sustain regional brain activation patterns lost in acute hypoglycaemia, with some restoration of cortical function and enhanced adrenaline responsiveness. A methodology has been established that may help in the development of therapies to protect against severe hypoglycaemia in insulin therapy for patients with diabetes and problematic hypoglycaemia. 相似文献
110.
The case report describes a distinct variant of non-REM (Rapid Eye Movement) arousal parasomnia, sleepwalking type, featuring repetitive abrupt arousals, mostly from slow-wave sleep, and various automatisms and semi-purposeful behaviours. The frequency of events and distribution throughout the night presented as a continuous status of parasomnia (' status parasomnicus '). The patient responded well to treatment typically administered for adult NREM parasomnias, and after careful review of the clinical presentation, objective findings and treatment outcome, sleep-related epilepsy was ruled out in favour of parasomnia. 相似文献