经方组合临床运用举隅(三)

3经方配时方3.1小青龙汤配观音应梦散治疗感冒咳嗽刘某,男,60岁,2007年11月初诊。患者反复感冒咳嗽3个月,初期疏于治疗,到严重时又杂乱服药,服过各种抗生素、止咳糖浆之类,时好时坏,未曾歇止。近几天,工作压力大,精神极度疲乏,咳至通宵不眠,一阵阵畏寒,咽喉突发奇痒时,即气促咳嗽,     

舟山市3例发热伴血小板减少综合征的病原学与遗传特征

目的 对舟山市3例疑似发热伴血小板减少综合征(SFTS)病例进行病原学鉴定、确诊,并分析其遗传特征.方法 选用巢式RT-PCR测定新布尼亚病毒核酸及L、M、S3个特异性基因,并对基因扩增产物进行测序,测序结果与GenBank上公布的序列进行比对确认.用DNAStar软件构建进化树与序列距离表.用间接免疫荧光法测定患者恢复期和急性期血清新布尼亚病毒IgG抗体滴度.结果 3例SFTS患者急性期血清中均能检测到新布尼亚病毒的3个特异性基因片段,其中S基因核苷酸序列与舟山市同类基因核苷酸序列的同源性在94.4％～ 100.0％,患者恢复期血清病毒抗体滴度较急性期增高4倍以上.结论 经过病原学鉴定,3例临床疑似患者确诊为发热伴血小板减少综合征的新近感染病例.舟山市新布尼亚病毒的遗传特征比较稳定.     

泪道探通术联合硅胶管植入术治疗鼻泪管阻塞的护理研究

目的探讨泪道探通术联合硅胶管植入术的临床护理对提高鼻泪管阻塞患者的治愈率,缓解患者生理、心理上痛苦的效果。方法筛选2011年10月-2013年10月就诊于武警后勤学院附属医院眼科的50例(50眼)鼻泪管阻塞患者,通过泪道探通术联合硅胶管植入术进行治疗,并对其实施围术期护理和出院指导,观察其预后疗效。结果治愈42眼,好转6眼,无效2眼,有效率:治愈+好转=96%。结论通实施对泪道探通术联合硅胶管植入术的围术期护理和出院指导,可提高鼻泪管阻塞患者的治疗成功率,从而使患者的疾病得到改善,生活质量得到提高。     

Prevalence of SFTSV among Asian House Shrews and Rodents,China, January–August 2013

To evaluate the role of small mammals as hosts of severe fever with thrombocytopenia syndrome virus (SFTSV), we tested serum samples from rodents and shrews in China, collected in 2013. SFTSV antibodies and RNA were detected, suggesting that rodents and shrews might be hosts for SFTSV.     

Serum cortisol level and disc displacement disorders of the temporomandibular joint

Temporomandibular disorders (TMD) are a significant public health problem, affecting approximately 5–12% of the population. Objectives: This retrospective cross‐sectional study investigated the relationship between 8 AM serum cortisol levels (8ASC) and disc displacement disorders (DDD) of TMD. One hundred and forty patients with DDD were recruited. Among them, 60 patients comprised the case group of disc displacement without reduction with limited opening (DDWORWLO, age 37·7 ± 17·22), and 80 were ‘other DDD’ for the control group (age 36·4 ± 13·08). The independent variables included domains of demography, history, malocclusion, comorbid symptoms, comorbid TMD and 8ASC. Data were analysed with the chi‐square test, logistic regression and receiver operating characteristic (ROC) curve. Results of multiple logistic regression showed that 8ASC was the only factor significantly related to DDWORWLO (P = 0·006). Receiver operating characteristic analysis of DDWORWLO and 8ASC indicated an area under the curve of 0·669, standard error of 0·049 and P value of 0·001. The adequate cut‐off point of 8ASC was 12·45 (μg dL^?1), with sensitivity of 0·636, and specificity of 0·729. 8 AM serum cortisol level can be used as a clinical clue to differentiate DDWORWLO from other DDD.