曲安奈德球后注射联合黄斑格栅样光凝治疗黄斑水肿

目的：探讨曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗黄斑水肿的临床疗效与安全性。
　　方法：选择我院2009-07/2013-11间收治的150例150眼黄斑水肿患者,按照数字随机法分为研究组(75例75眼)与对照组(75例75眼),对照组患者采用黄斑格栅样光凝治疗,研究组采用曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗,分别于治疗前,治疗后7 d;1,3,9 mo检测患者最佳矫正视力,并行光学相干断层扫描( optical coherence tomography, OCT )和荧光素眼底血管造影( fundus fluorescein angiography,FFA)检测。
　　结果：治疗后两组患者视力均明显改善(P<0.05),研究组术后7 d;1,3,9 mo的视力改善情况明显优于对照组及手术前(P<0.05);研究组术后7d;1,3,9mo时视网膜黄斑中心凹神经上皮层厚度显著降低(P<0.05),对照组术后7 d;1,3,9 mo与治疗前相比视网膜黄斑中心神经上皮层厚度无统计学意义(P>0.05),研究组黄斑中心凹视网膜神经上皮层厚度显著低于对照组(P<0.05);研究组出现7例眼压轻度增高,经降眼压治疗后均恢复正常。
　　结论：曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗黄斑水肿的临床疗效确切,可以有效提高患者视力,降低黄斑水肿症状,安全可靠,适于临床推广与应用。     

Performance evaluation of cylindrical fiber optic light diffusers for biomedical applications

BACKGROUND AND OBJECTIVES: Dosimetry for intracavity and interstitial light delivery requires next to the knowledge of tissue optical properties and models describing light propagation in tissue also exact knowledge of the spatial light source emission characteristics. However, the emission characteristics of cylindrical diffusers are often ill defined by the manufacturer, and not regularly determined by the end user, thus limiting the attainable dosimetry accuracy. STUDY DESIGN/MATERIALS AND METHODS: Commercial cylindrical diffusers, with active diffusive lengths of 1-2 cm and outer diameters of 相似文献   

Nd:YAG laser excision of a giant gingival pyogenic granuloma of pregnancy

A 19-year-old Hispanic nullipara experienced the rapid growth of an oral lesion on the right lower gingiva which she had first noticed at 29 weeks gestation. The lesion interfered with oral hygiene and eating. At surgery, the lesion measured 3.5 × 2.5 × 2.0 cm. Biopsy confirmed a pyogenic granuloma (“granuloma gravidarum”). Panorex films showed no bony invasion. The lesion was excised using the Nd:YAG laser under general anesthesia when the patient had reached 36 3/7 weeks gestation. We chose the Nd:YAG laser over the CO₂ laser for the removal of this very vascular lesion, because of its superior coagulation characteristics. This technique results in removal of the lesion with less danger of bleeding than with any other surgical technique. The patient did well postoperatively, delivered a healthy 3,884 g infant at 40 6/7 weeks gestation, and has had no recurrence after 15 months of follow-up. © 1994 Wiley-Liss, Inc.     

Outcomes of combined treatments in patients with retinal arterial macroaneurysm

Purpose:To evaluate the outcome of the combined approach between intravitreal ranibizumab (IVR) and focal laser photocoagulation (FLP) in the treatment of symptomatic retinal arterial macroaneurysm (RAM).Methods:A total of 10 patients were included in this clinical case series report. They were diagnosed with symptomatic RAM (one eye in each) and assessed by a comprehensive ophthalmologic examination, including fluorescein angiography (FA), optical coherence tomography angiography (OCT-A), and indocyanine green angiography (ICGA). All patients were treated with an IVR followed by an FLP 2 weeks later. If necessary, a second IVR was given 1 month after the first one (or 2 weeks after the first FLP), which was followed by a second FLP treatment 2 weeks later in the needed cases. All cases were followed up for 6 months after the last treatment.Results:Both the retina hemorrhage and edema were resolved by the treatment. No ocular and/or systemic side effects were evident, and no recrudescence of RAM was seen within the 6 months of follow-up.Conclusion:The combined treatment of IVRs and FLPs was successful in the management of symptomatic RAM.     

中药合激光治疗糖尿病性视网膜病变临床观察

目的 :探讨糖尿病性视网膜病变的有效治疗方法。方法 :糖尿病性视网膜病变患者 92例 13 5眼 ,其中中药组 2 5例 5 0眼 ,内服益气养阴、补肾明目、活血化瘀之中药 ;激光组 3 1例 3 7眼应用激光治疗方法 ;中药联合激光组 3 6例48眼 ,应用激光 ,同时配合内服益气养阴、补肾明目、活血化瘀之中药。观察三组治疗前后视力、眼底的变化。结果 :中药联合激光组视力提高优于中药组、激光组 ;眼底出血、水肿、渗出吸收时间缩短 ;新生血管退缩较完全。结论 :中药联合激光组对糖尿病性视网膜病变的疗效最好 ;单纯型糖尿病性视网膜病变的疗效优于增殖型糖尿病性视网膜病变 ;在新生血管治疗方面 ,激光组和中药联合激光组疗效明显优于中药组。     

超声引导Nd：YAG激光凝固羊肝灰阶定量分析

本文报道超声引导ND:YAG激光凝固羊肝灰阶定量分析。经皮穿刺超声引导导入激光对羊肝进行组织间凝固(interstitial laser photocoagulation ILp),靶区进行灰阶定量分析,观察其灰阶变化规律。结果显示:随着激光功率及作用时间延长,靶区灰阶强度逐渐增加,很快达到最高强度,维持这一高强度水平,靶区以外肝组织灰阶强度无明显变化。说明激光作用靶区肉眼可见从一强光点到强光团,最后形成强回声区,而且,灰阶定量仪处理结果亦证明这一变化规律。结论:超声显像能准确显示激光作用靶区变化情况。     

532激光治疗视网膜静脉阻塞25例疗效分析

目的探讨532激光治疗视网膜静脉阻塞的疗效。方法532激光治疗25例视网膜静脉阻塞（retinal vein occlusion，RVO），23例随诊3～21个月。结果其中视网膜分支静脉阻塞（branch retinal vein occlusion，BRVO）的视力预后良好，视网膜中央静脉阻塞（central retinal vein occlusion，CRVO）视力改善不明显，缺血型视力预后差，激光治疗可防止或治疗新生血管形成和新生血管性青光眼（nevoascular glaucoma，NVG）。25例均有不同程度疗效。结论532激光治疗RVO安全有效且并发症少。定期随诊以及行眼底荧光造影以随时观察疗效是提高治愈率的关键。     

氪激光治疗视网膜黄斑分支静脉阻塞激光的临床观察

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Ahmed 引流阀植入联合全视网膜光凝和玻璃体腔注射 Avastin 治疗新生血管性青光眼

目的：评价Ahmed青光眼引流阀植入联合全视网膜光凝和玻璃体腔注射Avastin治疗新生血管性青光眼的临床疗效。方法回顾性分析我院2011年6月～2012年5月收治住院行Ahmed青光眼引流阀植入术联合全视网膜光凝和玻璃体腔注射Avastin治疗的20例（20只眼）新生血管性青光眼患者的临床资料。主要观察指标为手术前后视力、眼压、虹膜新生血管消退情况、并发症及手术成功率等,术后随访12～18个月。结果全视网膜光凝和玻璃体腔注射avastin后1周内20眼虹膜新生血管均不同程度消退。术后最后一次随访发现,20眼中仅有3眼联合抗青光眼药物眼压≤21mmHg,其余17眼术后眼压控制在正常范围,手术成功率达到85％．最后一次随访,平均眼压（15．31±4．27）mmHg,与术前平均眼压（49．03±12．87）mmHg比较,差异有统计学意义（P＝0．000）。视力提高者8眼（40％）,保持不变者10眼,下降2眼。术后并发症主要是早期的短暂性浅前房、高眼压及晚期的滤过道瘢痕纤维化。结论 Ahmed引流阀植入联合全视网膜光凝和玻璃体腔注射Avastin治疗新生血管性青光眼安全有效,有利于保护残留的视功能,手术成功率高,并发症少,可以作为新生血管性青光眼患者的首选手术方式之一。     

阿柏西普联合全视网膜激光光凝治疗缺血型视网膜中央静脉阻塞伴黄斑水肿的临床价值

目的 探讨阿柏西普联合全视网膜激光光凝治疗缺血型视网膜中央静脉阻塞(CRVO)伴黄斑水肿(ME)的疗效及其对患者视网膜血流和房水血管内皮生长因子(VEGF)、基质细胞衍生因子-1(SDF-1)的影响。方法 选择柳州市人民医院2018年3月至2020年12月收治的96例缺血型CRVO伴ME患者,采用随机数字表法分为观察组及对照组,各48例。观察组给予阿柏西普联合全视网膜激光光凝治疗,对照组单纯实施全视网膜激光光凝治疗。连续治疗12周,比较治疗前和治疗12周后两组最佳矫正视力(BCVA)[采用最小分辨角对数(log MAR)视力记录],黄斑中心凹厚度(CMT),视网膜血流参数[视网膜浅层毛细血管丛(SCP)血流密度、黄斑中心凹无血管区(FAZ)],以及房水VEGF、SDF-1水平。并根据BCVA改善情况、出血吸收情况、黄斑区荧光素渗漏消失情况、无灌注区消失情况、ME消失情况以及CMT恢复情况评价两组治疗效果,并评价安全性。记录两组治疗过程中不良反应情况,包括局部球结膜下出血、一过性眼压升高等。结果 观察组总有效率(93.75%)高于对照组(75%),差异有统计学意义(P<0.05)。...