推拿配合半刺法治疗小儿腹泻的临床观察

目的:观察推拿结合半刺法治疗小儿腹泻的疗效。方法:选择96例腹泻患儿作为研究对象,治疗组(n=48),予推拿配合半刺法治疗,对照组(n=48)予西药治疗,比较两组疗效。结果:治疗组48例,治愈41例,好转6例,无效1例,总有效率97.7%。对照组中,治愈20例,好转20例,无效8例,总有效率83.3%。结论:推拿结合半刺法治疗小儿腹泻优于西药组。     

梅花针叩刺与生姜片涂擦联合自体静脉血患处皮下与穴位注射治疗白癜风观察

[目的]观察梅花针叩刺与生姜片涂擦联合自体静脉血患处皮下与穴位注射治疗白癜风疗效。[方法]将26例门诊患者取卧位或坐位。治疗区皮肤常规消毒,采用梅花针在白斑区域按照从外向内呈同心圆样叩刺,以皮损部位潮红并伴有少量出血为度,叩刺后取生姜片2～3mm薄片涂擦患处,以局部发热发红为度。梅花针叩刺完成后,用2.5～5mL注射器于肘静脉取静脉血2.5～5mL(视皮损面积定量)将病变部位消毒,在白斑区分点皮内或皮下注射静脉血1～2mL/每点(以白斑区均匀分布为度),针孔处用干棉球压迫止血,每周2次,10次为1疗程;另取双侧肺俞、脾俞、肾俞、膈俞、曲池、足三里、血海、三阴交分成两组,每周分2次治疗,以上每组每个穴位注射0.5～1.0mL。每周治疗2次,10次(5周)为1个疗程,疗程间隔1个星期。[结果]痊愈16例,显效6例,有效2例,无效2例,总有效率92.31%。最短治疗1个疗程,最长8个疗程,平均3～5个疗程。[结论]梅花针叩刺与生姜片涂擦联合自体静脉血患处皮下与穴位注射治疗白癜风疗效满意。     

浅探“巨刺”与“缪刺”

巨刺与缪刺在临床治疗中运用广泛,二者存在相同之处,却适用于不同的病证,为此易为人误用。应从理论上区别二者,以指导临床应用,提高疗效。     

马栗树籽提取物（迈之灵）对肢体创伤患者血清细胞因子IL-6、IL-1β和TNF影响的研究

目的研究马栗树籽提取物（迈之灵）对肢体创伤软组织肿胀患者的血清细胞因子白细胞介素VI（IL-6）、白细胞介素1β（IL-1β）和肿瘤坏死因子（TNF）水平的影响。方法四肢骨折创伤患者120例采用双盲法,随机抽样分成观察组（60例）和对照组（60例）。观察组口服迈之灵片,对照组口服安慰剂片治疗,分别观察其肿胀和疼痛程度。2组均测量血清IL-6、IL-1β、TNF值。48例正常人测量血清IL-6、IL-1β、TNF值。结果骨折并软组织损伤患者血清IL-6水平在发病6 h内升高,24-36 h达到高峰,8 d后基本降至正常,重度组血清IL-6水平高于轻、中度组（6 h,P〈0.01;24-36 h,P〈0.05）,观察组用迈之灵治疗4 d后血清IL-6水平明显下降（P〈0.01）。创伤患者血清TNF、IL-1β水平升高,但持续时间短。结论迈之灵消除肢体骨折软组织肿胀效果明显,对轻、中度损伤患者的疗效优于重度损伤患者,能够明显降低患者血清IL-6水平,与其抗炎、抗渗出、抗氧自由基等作用相关,一定程度上减轻和保护了机体的应激反应。     

中药泡熏治疗足跟骨骨刺症临床疗效观察简

目的：观察中药泡熏治疗足跟骨骨刺症的疗效。方法：将60例足跟骨骨刺症的患者随机分为中药组和对照组,每组30例。观察组运用苏木、花椒、两面针、千斤拔、桑枝、三棱、莪术、宽经藤的药液进行泡熏患足的治疗。对照组口服布洛芬缓释胶囊。10 d为1个疗程,治疗两个疗程后统计临床疗效和进行VAS评分。结果：中药组临床治愈率为66.7%（20/30）,对照组为23.3%（7/30）,中药组优于对照组（P〈0.01）。VAS评分结果：中药组临床治愈率为66.7%（20/30）,对照组为20.0%（6/30）,中药组优于对照组（P〈0.01）。结论：中药泡熏治疗足跟骨骨刺症的临床疗效优于对照组。     

An unusual journey of a periocular date palm thorn

An 8-year-old boy presented with a left lower lid swelling of one month duration. His parents gave a history of date palm thorn injury on left side of the forehead three months back which was removed partially by a local doctor. On examination, there was a left infraorbital swelling with diffuse oedema of the left sided cheek and temporal fossa. A scar mark (entry wound) was detected over the left eyebrow. Three-D configuration of contrast enhanced computed tomography (CECT) of the orbit showed a linear foreign body behind the zygomatic bone. The lower lid mass was excised, the date palm thorn was recovered from a pocket behind the zygomatic bone. Histopathology of the excised mass showed presence of granulation tissue. We describe the management of such a rare case along with review of literature.     

马栗种子提取物治疗黄斑水肿的临床疗效观察

目的:观察口服马栗种子提取物对黄斑水肿的临床疗效。方法:将黄斑水肿患者47例50眼随机分为2组,对照组采用常规促吸收疗法(口服维生素C,E和芦丁片),治疗组在常规治疗基础上加用马栗种子提取物口服,4wk为1疗程。结果:治疗组黄斑水肿吸收优于对照组,两组差异有显著意义(P<0.05),治疗组患者无1例不良反应。结论:马栗种子提取物对黄斑水肿疗效确切,无不良反应,可在临床上推广应用。     

Anti-Inflammatory Effects of Water Chestnut Extract on Cytokine Responses via Nuclear Factor-κB-signaling Pathway

Water chestnut (Trapa japonica Flerov.) is an annual aquatic plant. In the present study, we showed that the treatment of water chestnut extracted with boiling water resulted in a significant increase 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity and decrease the intracellular H₂O₂-induced accumulation of reactive oxygen species. In addition, water chestnut extract (WCE) inhibited lipopolysaccharide (LPS)-induced nitric oxide production and suppressed mRNA and protein expression of the inducible nitric oxide synthase gene. The cytokine array results showed that WCE inhibited inflammatory cytokine secretion. Also, WCE reduced tumor necrosis factor-α-and interleukin-6-induced nuclear factor-αB activity. Furthermore, during sodium lauryl sulfate (SLS)-induced irritation of human skin, WCE reduced SLS-induced skin erythema and improved barrier regeneration. These results indicate that WCE may be a promising topical anti-inflammatory agent.     

PHOENIX DATE PALM INJURIES: A REVIEW OF INJURIES FROM THE PHOENIX DATE PALM TREATED AT THE STARSHIP CHILDREN’S HOSPITAL

Background : The purpose of this study was to review patients treated for penetrating Phoenix date palm injuries. Documentation of the clinical behaviour of these injuries was sought as they have different clinical outcomes to other foreign body injuries. Methods : Data was collected via a retrospective review of patient files and imaging studies of all patients with foreign body injury admitted to the Orthopaedic Service of Starship Children’s Hospital between 1992 and 1997. Results : Of 250 patients admitted with foreign body injuries, 21 cases were identified as caused by the Phoenix date palm. The age range was 5 to 12 years. There was a median delay of 43 days between the time of injury and presentation to hospital. An average of 1.3 operations were performed on each patient. Ultrasound was used in 12 cases, foreign body was identified in 10 patients— a sensitivity of 83%. Intraoperative ultrasound was also found to be beneficial in three of these cases. Conclusions : Phoenix date palm injuries often have a protracted course. The initial diagnosis and treatment of such injuries is often delayed. Fracturing and fragmentation of the barbs may occur and multiple surgical procedures may be required to remove all of the foreign material. The Phoenix date palm barbs may cause a severe tissue reaction with sterile granulomatous synovitis and bony pseudo‐tumour formation. A high level of suspicion on history taking and surgical exploration is needed. Total synovectomy for delayed joint or tendon sheath involvement may be required when fragmentation has occurred. Ultrasound has higher sensitivity for detection of thorn foreign bodies than magnetic resonance imaging.