浅刺加推拿治疗面瘫132例疗效观察

目的：探索针刺治疗面瘫的更有效方法.方法：按就诊顺序随机分成治疗组76例,给予浅刺患侧面部加头颈部推拿治疗.对照组56例以常规捻转针刺法加头颈部推拿治疗.结果：两个疗程后,治疗组总有效率96.1%,对照组总有效率87.4%,P＜0.05,两组疗效有显著性差异.结论：浅刺患侧的治疗效果明显优于对照组.     

点刺放血法联合银蓝化斑汤治疗玫瑰糠疹30例

目的观察点刺放血法联合银蓝化斑汤治疗玫瑰糠疹的临床疗效及安全性。方法将60例门诊玫瑰糠疹患者随机分为治疗组和对照组,分别采用点刺放血法联合银蓝化斑汤治疗玫瑰糠疹和点刺放血法联合氯雷他定片治疗,观察两组疗效与不良反应。结果治疗组有效率93.3%,不良反应率3%。对照组有效率52%,不良反应率23%。两组有效率和不良反应率比较,差异均有统计学意义（P均〈0.05）。结论采用点刺放血法联合银蓝化斑汤治疗玫瑰糠疹是安全有效的。     

Prosopis spicigera and Skin Granulomas/Prosopis spicigera und Hautgranulome

Summary: A thorn of Prosopis spicigera has been detected in vivo in two cases of chronic skin granulomas. It coexisted with an actinomycotic mycetoma in one case. In the other case there was no foreign body giant cell reaction or mycetoma. The relationship between a thorn prick and the development of mycetoma is re-emphazised.
Zusammenfassung: Bei zwei Patienten mit chronischen Hautgranulomen wurden Dornen von Prosopis spicigera im Gewebe entdeckt. In einem Fall bestand gleichzeitig ein actinomykotisches Myzetom. Bei dem anderen Fall wurde weder ein Myzetom noch eine Fremdkörperreaktion entdeckt Der kausale Zusammenhang zwischen einer Verletzung durch Dornen und der Entstehung von Myzetomen wird nochmals betont.     

山楂叶总黄酮磷脂复合物的研究

目的 研究山楂叶总黄酮磷脂复合物的制备方法并对复合物的形成进行验证.方法 以无水乙醇作为反应溶剂;磷脂与药物的比例为2:1,反应物质量浓度为20 mg/mL;60℃搅拌2 h至反应液澄清,除去溶剂后将能溶于二氯甲烷的物质真空干燥即为药物与磷脂的复合物;采用紫外光谱分析、红外光谱分析,差示扫描分析对复合物的形成进行验证.结果 该方法简单可行,山楂叶总黄酮与磷脂的复合率达96%以上.复合物的光谱分析与反应物单体及物理混合物有一定的差别.结论 磷脂复合物给药系统能够应用于某些中药提取物,但与多种成分形成复合物的机制有待进一步研究.     

Insuffisance cardiaque chronique et réadaptation à l’effort sous bêtabloquants

In patients with chronic heart failure, the efficacy of beta-blocker therapy on mortality and the multiple benefits observed with physical training justify the association of the both. The effects of betablockade on different systems solicited in the exercise, particularly on the cardiocirculatory response during exercise test, rise many questions about the impact of beta blocker treatment on the changes induced by physical training. The cardioselective and vasodilating properties of beta-blockers play a role. It seems that the improved performance assessed by peak oxygen uptake (peak VO2) resulting from physical training is not limited by the beta-blocker treatment in patients with chronic heart failure. Synergistic effects have been observed, but many issues remain unsolved.     

马栗树籽提取物（迈之灵）治疗肢体创伤的临床研究

目的观察马粟树籽提取物（迈之灵）治疗肢体骨折软组织肿胀的临床疗效及其对损伤指标——血清过氧化氢酶（SOD）、谷胱甘肽还原酶（GSH）、过氧化脂质（LPO）等水平的影响。方法四肢骨折软组织创伤患者1944例。采用双盲法,随机抽样分成治疗组1296例,对照组648例,治疗组口服迈之灵片治疗,对照组口服安慰剂药丸治疗,分别进行疗效观察研究。治疗组抽取61例患者测量用药前后血清SOD、GSH、LPO值。结果临床观察组有效率为94．6％,显效率为75．5％,对照组有效率为48．4％,显效率为35．2％。差异有统计学意义（P〈0．05）。肢体创伤肿胀病人患者血清均存在高水平LPO及低水平SOD、GSH。结论迈之灵治疗肢体骨折软组织肿胀效果明显,值得临床推广应用。其拮抗氧自由基损伤可能是迈之灵治疗肢体骨折、软组织损伤的机制之一。     

浅针多刺开络气针法治疗顽固性湿疹56例临床观察

湿疹是由多种内外因素引起的表皮及真皮浅层的皮肤炎症性反应,以皮疹多形性,有渗出倾向,剧烈瘙痒,夜间尤甚,易复发为特点。按皮损特点分为急性湿疹,亚急性湿疹和慢性湿疹。本篇讨论的为顽固性湿疹,多属于慢性湿疹,或者由急性,亚急性湿疹久治不愈,反复发作,形成顽固性湿疹。其表现为患处皮肤浸润肥厚,表面粗糙,呈暗红色或伴色素沉着,皮损多为局限性斑块。我们以中医脏腑辨证,经络辨证为主,结合气血津液辨证等其他辨证方法,辨证论治,运用浅针多刺开络行气针法治疗顽固性湿疹56例．具体情况如下。     

Anticholinergic intoxication with commercially available thorn apple tea

Abstract

Two adolescents were admitted to the hospital with acute psychosis and peripheral signs of anticholinergic intoxication. Atropine intoxication due to drinking tea made from thorn apple (Datura stramonium) was diagnosed. After conservative treatment recovery was complete.     

浅刺针法合通窍活血汤对脑梗死大鼠血浆TXB_2和6-酮-PGF1α水平的影响

目的研究浅刺针法合通窍活血汤对脑梗死大鼠血浆TXB2和6-酮-PGF1α水平的影响。方法将150只SD大鼠随机分为5组,Ⅰ、Ⅱ、Ⅲ、Ⅳ组均予脑梗死造模,Ⅴ组行假手术,之后Ⅰ组浅刺针法合通窍活血汤治疗,Ⅱ组予常规针法合通窍活血汤,Ⅲ组仅予通窍活血汤,Ⅳ组和Ⅴ组不予处理。各组于造模后2,7,14 d随机取10只大鼠采用放射免疫法测定大鼠血浆TXB2和6-酮-PGF1α的含量,并进行统计学处理。结果Ⅰ、Ⅱ、Ⅲ、Ⅳ组造模后血浆TXB2水平明显高于Ⅴ组(P均<0.01);与Ⅱ、Ⅲ、Ⅳ组比较,Ⅰ组TXB2水平下降更快(P均<0.01)。Ⅱ、Ⅲ、Ⅳ组6-酮-PGF1α显著低于Ⅴ组(P均<0.01);与Ⅱ、Ⅲ、Ⅳ组比较,Ⅰ组6-酮-PGF1α水平升高更快(P<0.01)。结论浅刺针法合通窍活血汤能更有效地降低TXB2水平,升高6-酮-PGF1α水平,使TXB2/6-酮-PGF1α比值趋向平衡,从而达到治疗脑梗死的目的。     

Chestnut extract induces apoptosis in AGS human gastric cancer cells

In Korea, chestnut production is increasing each year, but consumption is far below production. We investigated the effect of chestnut extracts on antioxidant activity and anticancer effects. Ethanol extracts of raw chestnut (RCE) or chestnut powder (CPE) had dose-dependent superoxide scavenging activity. Viable numbers of MDA-MD-231 human breast cancer cells, DU145 human prostate cancer cells, and AGS human gastric cancer cells decreased by 18, 31, and 69%, respectively, following treatment with 200 µg/mL CPE for 24 hr. CPE at various concentrations (0-200 µg/mL) markedly decreased AGS cell viability and increased apoptotic cell death dose and time dependently. CPE increased the levels of cleaved caspase-8, -7, -3, and poly (ADP-ribose) polymerase in a dose-dependent manner but not cleaved caspase-9. CPE exerted no effects on Bcl-2 and Bax levels. The level of X-linked inhibitor of apoptosis protein decreased within a narrow range following CPE treatment. The levels of Trail, DR4, and Fas-L increased dose-dependently in CPE-treated AGS cells. These results show that CPE decreases growth and induces apoptosis in AGS gastric cancer cells and that activation of the death receptor pathway contributes to CPE-induced apoptosis in AGS cells. In conclusion, CPE had more of an effect on gastric cancer cells than breast or prostate cancer cells, suggesting that chestnuts would have a positive effect against gastric cancer.