蝎精酒的遗传毒理学研究

蝎精酒原名"蝎精神功酒",是新开发的保健性食品,具有免疫调节作用.为了保证该产品的安全性,对其遗传毒性进行了较为系统的检测,实验结果证明:蝎精酒服用安全,无遗传毒性.     

High-alcohol-content flavored alcoholic beverages (supersized alcopops) should be reclassified to reduce public health hazard

In the US, underage drinkers often consume supersized alcopop – a high-alcohol-content, ready-to-drink flavored alcoholic beverage that is currently regulated as beer. However, calculations in this paper illustrate how the high alcohol by volume and low price of supersized alcopops suggest that they rely on a larger proportion of additives for their alcohol content than permitted to meet the legal definition for beer. From a public safety perspective, it is urgently important that the Alcohol and Tobacco Tax and Trade Bureau assess the formulation of supersized alcopops – specifically, the percent of alcohol in the finished product that is derived from additives. Appropriate reclassification of supersized alcopops as distilled spirits would reduce youth access by resulting in increased price and reduced availability at the retail locations where youth most often obtain alcohol.     

急性胰腺炎35例发病因素分析

目的探讨急性胰腺炎的发病因素、治疗及预防措施。方法回顾性分析35例急性胰腺炎患者的临床资料。结果32倒于治疗7～10d胰病消失，血淀粉酶正常。死亡3例，均为病前嗜酒或进食高脂饮食者。结论饮酒、进食高脂饮食、暴饮暴食是引起急性胰腺炎的发病因素。     

A tool for the evaluation of colour in port wine stains

A simple method for immediate comparison of the aesthetic results of laser treatment of port wine stains has been developed. This method could easily be implemented in the offices of laser specialists throughout the world.The method consists of a colour strip that is viewed together with the lesion. The colours have been chosen from the MUNSELL standard colour system. After extensive testing eight colours were chosen that appear visually equally spaced and represent the various colours of port wine stains before and during their treatment.Using this standard would allow a much more objective analysis of the results of different techniques and lasers. Just as importantly it gives the patients an objective indication of their progress during treatment.     

Lichtschutz durch Rotwein?

Background: There is increasing evidence that polyphenols, antioxidants from plants such as green tea or grapes, may impair the UV‐induced erythema reaction as well as carcinogenesis and metastasis of melanoma and epithelial skin cancer. The UVB‐protective potential of wine polyphenols has not been studied so far in humans. Patients and Methods: We tested the influence of local and systemic application of three red wines on the minimal erythema dose (MED) after UVB exposure in 15 healthy male physicians. Baseline MED were determined in all subjects. Irradiation was carried out prior to and immediately following 20 minutes of occlusive application of red wine as well as 12 % alcohol to the back. The systemic effect was tested by ultraviolet irradiation immediately prior to oral intake, Results: There were no topical effects. Wine A also provided no protection sys‐temically. Drinking wine B has led to an almost significant rise of MED, while wine C, which had the highest polyphenol content, produced a statistically significant higher MED (p = 0.031). Conclusions: “Wine baths” will not have sun protective properties. A significant rise of the MED following oral intake of the wine with the highest polyphenol content might be due to these substances. Further research is needed to clarify the role of polyphenol content, dose and duration of wine consumption.     

~(60)钴辐射酒致突变及饮用潜在危害研究

用Ａｍｅｓ试验检测了２０Ｇｙ６０钴辐射的白兰地酒。结果发现：ＴＡ９８与ＴＡ１００菌株在±Ｓ９时的致突变率均＜２，无致突变作用。用１０名健康人饮用，观察有否潜在危害，结果：血红细胞、白细胞、血红蛋白、谷丙转氨酶与锌浊度均正常，饮酒前后没有差别（Ｐ＞００５）；尿液Ａｍｅｓ试验，ＴＡ９８与ＴＡ１００菌株回变菌落呈阴性致突变反应（致突变率＜２）。上述结果说明，６０钴辐射酒无潜在危害。     

Tunable dye laser (577 nm) treatment of port wine stains

Despite steady improvement in the laser treatment of port wine stains (PWS), hypertrophic scarring remains a serious side-effect in approximately 10% of patients. The tunable dye laser (577 nm) has been shown to cause selective vascular destruction in normal and PWS skin. We have treated ten patients using a tunable dye laser (577 nm, 300 mu sec) resulting in clearing of the PWS without any evidence of hypertrophic scarring. Treatment requires no anesthesia or wound care, and there were no postoperative infections.     

光敏剂漂白特性在鲜红斑痣光动力治疗中的作用

目的：监测光动力治疗过程中鲜红斑痣组织内光敏剂含量的动态变化，探讨光敏剂漂白特性在光动力疗法微血管选择机制中的作用。方法：鲜红斑痣病人34例，男性15例，女性19例，静脉注射血啉甲醚和血卟啉衍生物5mg/kg后给予铜蒸气激光照射，使用三倍频Nd:YAG激光和光学多通道分析仪（OMA）在治疗前和治疗中的多个时间点对治疗区皮肤组织进行荧光光谱检测，绘制成时间－荧光强度曲线。结果：治疗区皮肤组织中光敏剂荧光强度在激光照射开始后迅速下降，血啉甲醚荧光强度的下降速率和下降幅度均显著大于血卟啉衍生物。结论：治疗区皮肤组织中光敏剂的漂白速度明显大于光敏剂的补充扩散速度，光敏剂漂白可能是光动力疗法微血管选择效应的主要机制。