带隐神经交腿随意皮瓣修复足底皮肤缺损

目的 报道用带隐神经的小腿内侧带蒂随意皮瓣修复对侧足底皮肤缺损的临床效果。方法 在健侧小腿内侧隐神经走行区设计皮瓣，将隐神经保留在皮瓣中央，根据患足创面大小切取皮瓣，带深筋膜，蒂保留在胫前侧，将皮瓣缝合于患足的创面，皮瓣中的隐神经与患足足底内侧皮神经吻合，双下肢固定3周后断蒂。1997～2001年，临床应用13例。结果 用该皮瓣修复13例足底皮肤缺损均获得成功，皮瓣外形良好，术后6～12个月恢复感觉，无再破溃发生。结论 带隐神经交腿随意皮瓣切取简单，厚薄适度，不损伤知名血管，术后带感觉神经可恢复皮瓣的感觉，有效防止皮瓣再破溃。是修复足底皮肤缺损的较好方法。     

Effects of capsaicin in temporomandibular joint arthritis in rats

Temporomandibular joint (TMJ) arthritis was induced in female Lewis rats by unilateral injection of a suspension of heat-killed Mycobacterium butyricum in paraffin oil into the TMJ. Control rats received paraffin oil by the same route. Arthritic and control rats were pretreated either with capsaicin or denervation of the mandibular branch of the trigeminal nerve. Tissues were collected for neuropeptide extraction and analysed by radioimmunoassay and reverse-phase high-performance liquid chromatography. In all groups, the levels of substance P- (SP), calcitonin gene-related peptide- (CGRP) and neuropeptide Y- (NPY) like immunoreactivity (LI) were higher in the trigeminal ganglia than in the TMJs. In control rats, capsaicin significantly lowered the levels of SP-LI in the trigeminal ganglia and TMJ, but not CGRP-LI and NPY-LI. In the arthritic rats, capsaicin pretreatment significantly lowered the SP-LI and CGRP-LI in the trigeminal ganglia and TMJ, but not the NPY-LI. In the trigeminal ganglia the unilateral denervation significantly lowered SP-LI in control rats, and in arthritic rats SP-LI and CGRP-LI. On the denervated side of the arthritic TMJ, NPY-LI, SP-LI and CGRP- LI were significantly lowered as compared to the arthritic control rats and to the contralateral side. In this rat model, pretreatment with capsaicin and surgical denervation decreased the neuropeptide content in the trigeminal ganglia and the TMJ. The results clearly demonstrate a close interaction between increased neuropeptide release from sensory and sympathetic neurones after induction of arthritis in the rat.     

儿童原发性腹膜后恶性肿瘤的诊断与治疗

分析原发性腹膜后恶性肿瘤１２例。８３％以腹块和腹痛为主要症状，体征中腹块占９１．５％，以恶性淋巴瘤居首位占６１％。全组完全切除率为５８％，行脏器联合切除占２５％。完全切除加放疗、化疗３年存活率为２８．５％，部分切除及活检未给其它治疗者５例预后差，均１年内死亡，差别显著。     

永存左上腔静脉在心脏直视手术中的处理

自1981年8月至1996年10月施行心脏直视手术1800例，发现永存左上腔静脉（PLSVC）11例，其中引入左心房1例。全部并发于其它心内畸形，且无特异体征。认为本中仔细探查是对PLSVC诊断的重要环节。本文对注意事项以及对不同类型的PLSVC引流入左房的外科处理方法进行了阐述。     

先天性胆总管囊肿23例的术式及疗效分析

目的：探讨先天性胆总管囊肿的术式及疗效。方法：回顾分析手术治疗先天性胆总管囊肿23例，其中Roux-Y囊肿-空肠吻合8例；囊肿切除，Roux-Y肝总管-空肠吻合15例。结果：20例获得随访，Roux-Y囊肿-空肠吻合随访6例，仅2例无症状，另4例反复发作腹痛，发热或黄疸，其中1例再手术，囊肿切除，Roux-Y肝总管-空肠吻合随访14例。仅1例有腹痛，余13例无症状，结论：Roux-Y肝总管-空肠吻合是治疗先天性胆总管囊肿的首选术式。     

原发性甲状腺功能亢进症合并甲状腺癌18例分析

目的：探讨原发性甲状腺功能亢进症（甲亢）合并甲状腺癌（甲癌）的诊断和治疗。方法：回顾分析1990年1月于2000年1月手术治疗18例甲亢合并甲癌患者的临床资料，结果：微小癌占83％（15／18）。术前彩超检查15例，14例发现可疑结节；13例行癌侧叶全切除和对侧叶次全切除术，5例行双侧叶次全切除术，其中3例同时行颈淋巴结清扫术，1例二次行颈淋巴结清扫术。随访16例，平均随访7年，1例死于癌肺转移，余者仍存活，结论：术前常规彩超检查发现可疑结节有助于术中冰冻切片病理检查，手术治疗应兼顾甲亢和甲癌。     

335例术后全身炎症反应综合征的临床分析

【目的】了解手术创伤对术后全身炎症反应综合征 (SIRS)的影响。【方法】搜集外科重症监护室 (SICU) 335例患者的术后资料 ,分析不同手术组SIRS发病率 ;手术时间、失血量与SIRS持续时间的关系 ;SIRS持续时间与术后并发症的关系。【结果】术后SIRS发病率为 75 8% ,大手术高达 92 4 % ;无并发症患者失血量与SIRS持续时间呈正相关 (r1=0 783,P<0 0 1) ,手术时间与SIRS持续时间呈正相关 (r2 =0 398,P <0 0 1) ;随着SIRS持续时间延长 ,并发症发病率显著增高 (P<0 0 5 )。【结论】术后SIRS发生、发展与手术创伤密切相关 ;监测SIRS进程有助于及早发现并发症     

异位妊娠的腹腔镜手术临床分析

目的探讨电视腹腔镜手术治疗内出血异位妊娠的安全性和可行性。方法回顾分析2000年8月￣2004年8月该院电视腹腔镜手术治疗的15例伴有内出血的异位妊娠(出血量大于800mL,观察组)及同期30例无明显内出血异位妊娠病人的临床资料(对照组)。结果15例病人均手术成功,无中转开腹及并发症发生,两组手术时间及手术后住院时间均无明显差异。结论随着腹腔镜手术操作技巧、麻醉和监护技术的提高,腹腔镜手术治疗内出血甚至休克型异位妊娠在一定条件下是安全可行的。     

应用预控出血的包皮中远段环形剥除术治疗包皮过长

Objective To investigate the middle and distal circum peeling with bleeding control technique for redundant prepuce. Methods The middle and distal part of prepuce was eireum peeled with bleeding control and electrical scalpel. More preputial inner plate was reserved. Results From January 2004 to July 2008, 51 patients with redundant prepuce were treated with this procedure. The average blood loss was 1 ～2 ml with minimal edema. The proportion of inner and outer plates was suitable. Conclusions This teelmique has the advantages of minimal blood loss and slight edema. The cosmetic result is also satisfactory.