首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   94085篇
  免费   8779篇
  国内免费   2694篇
耳鼻咽喉   1258篇
儿科学   1848篇
妇产科学   1510篇
基础医学   6386篇
口腔科学   2046篇
临床医学   14482篇
内科学   11425篇
皮肤病学   2526篇
神经病学   4844篇
特种医学   2242篇
外国民族医学   6篇
外科学   6076篇
综合类   12962篇
现状与发展   4篇
一般理论   3篇
预防医学   14534篇
眼科学   1281篇
药学   10975篇
  265篇
中国医学   6929篇
肿瘤学   3956篇
  2024年   1171篇
  2023年   2035篇
  2022年   3180篇
  2021年   4437篇
  2020年   4408篇
  2019年   3681篇
  2018年   3460篇
  2017年   3805篇
  2016年   3697篇
  2015年   3691篇
  2014年   6622篇
  2013年   7182篇
  2012年   6098篇
  2011年   6168篇
  2010年   4852篇
  2009年   4614篇
  2008年   4639篇
  2007年   4540篇
  2006年   3973篇
  2005年   3391篇
  2004年   2795篇
  2003年   2362篇
  2002年   1896篇
  2001年   1657篇
  2000年   1333篇
  1999年   1183篇
  1998年   920篇
  1997年   898篇
  1996年   774篇
  1995年   754篇
  1994年   632篇
  1993年   520篇
  1992年   545篇
  1991年   441篇
  1990年   360篇
  1989年   366篇
  1988年   333篇
  1987年   308篇
  1986年   241篇
  1985年   276篇
  1984年   223篇
  1983年   171篇
  1982年   190篇
  1981年   151篇
  1980年   125篇
  1979年   96篇
  1978年   80篇
  1977年   64篇
  1976年   49篇
  1975年   38篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
The mechanism of oxygen reduction on the as-polished and corroded zinc specimens has been studied using a rotating ring disc electrode (RRDE) system. On the as-polished surface, oxygen was reduced into two distinct steps. In the first step, about 44% of O2 was reduced to H2O2 in a 2-electron reaction with the rest being reduced to OH? in a 4-electron reaction. On the other hand, in the second step, with the increase of overpotential O2 was almost exclusively reduced to OH? in a 4-electron reaction. The first step reduction occurred on an air-formed oxide-covered surface at more positive potential than ?1.2 V vs. Ag/AgCl and the second step reduction (E < ?1.2 V) took place on a semi-uniformly active surface. On the corroded surface, the second step was not distinctly observed on the polarization curve, because reduction of the zinc corrosion products simultaneously took place around ?1.2 V. The O2 reduction in the first step was inhibited by deposition of the corrosion products, though the ratio of amount of O2 reduced to OH? in a 4-electron reaction was larger than that on the as-polished surface. The mechanism of oxygen reduction is discussed on the basis of results obtained from the RRDE experiment.  相似文献   
72.
Summary  The aim of this study was to explore the relationship between patterns of missing occlusal units (OUs) and oral health-related quality of life (OHRQoL) in subjects with the shortened dental arches (SDAs). Subjects with SDAs were recruited consecutively for 1 month from six university-based prosthodontic clinics. In total, 115 SDA subjects participated (mean age, 58·5 ± 10·0 years; 71% female). The location and number of missing teeth were examined and the number of missing OUs was calculated. To evaluate OHRQoL, the Japanese version of the Oral Health Impact Profile (OHIP-J) was administered and the summary score of OHIP-J was calculated. The SDA subjects were categorized depending upon the anterior-posterior lengths of the missing or remaining OUs. Regression analyses were performed to investigate the OHIP-J differences between groups of subjects with various anterior–posterior SDA lengths. The analyses revealed that subjects who only lost the second molar contact exhibited significantly better OHRQoL than those who lost more teeth [coefficient: 11·1, 95% confidence interval (CI): 2·8–19·2, P  = 0·02]. Furthermore a statistically significant group difference was observed between the groups with and without the first molar occlusal contact (coefficient: 12·8, 95% CI: 1·4 to 24·1, P  = 0·03). In conclusion, although our results are of exploratory nature and need validation, patterns of missing OUs are likely to be related to the OHRQoL impairment in SDA subjects with the presence of first molar contact having a particularly important role.  相似文献   
73.
青少年产生正畸治疗需求动机的影响因素   总被引:10,自引:2,他引:10  
目的:研究各种主、客观因素对青少年产生正畸治疗需求动机的影响。方法:随机抽取11岁~13岁青少年300名(男女各半),做问卷调查,测量研究模型,获得被测试的治疗优先指数(treatmentpriorityindex,TPI)等级。结果:1.青少年的认知水平和对外界反馈的认知均与治疗需求显著相关;2.性别因素、家长因素及客观畸形程度都对治疗需求产生影响。结论:青少年正畸治疗需求动机的产生受社会心理因素及客观畸形程度的影响  相似文献   
74.
The aim of orthognathic surgery is to produce a more aesthetic facial skeletal appearance, and improve jaw function. This prospective study, aimed to evaluate the impact of orthognathic surgery on quality of life for patients with dentofacial deformity, and whether it was clinically meaningful. 62 consecutive patients were recruited (27 male, 35 female) aged 18–38 years. Baseline data were collected using a validated health status measure (Orthognathic Quality of Life Questionnaire (OQLQ)) and a visual analogue scale (VAS). Postoperative questionnaires (OQLQ, VAS) and a Global Transition Scale (GTS) were completed at 6 months after completion of treatment and compared with pre-treatment scores. Following surgery, there was a significant (p < 0.05, paired t test) improvement in OQLQ scores for each domain. The proportion of patients reporting a moderate or large improvement was: facial appearance (93%), chewing function (64%), comfort (60%) and speech (32%). Clinical relevance of change scores was reported in terms of effect sizes, and the largest effect was on facial aesthetics. The clinical impact was moderate on social aspects of deformity and oral function and a small effect on awareness of facial deformity. This research reaffirms that orthognathic surgery has positive effects on quality of life.  相似文献   
75.
Objectives : This study compares the distributional and psychometric properties of the Geriatric Oral Health Assessment Index (GOHAI) in two samples of older adults, and examines how the self-perceived impact of oral disease, as measured by the GOHAI, varies in accordance with sample sociodemographic and health characteristics. Methods : Results are based on survey data from two samples of older men: a Medicare sample of patients using community physicians (n=799; mean age=74) and users of VA ambulatory health care (n=542; mean age=72). Results : The findings indicated significant differences between samples in mean GOHAI scores, with the VA sample exhibiting worse scores. A number of similarities in psychometric properties of the instrument across the two samples were found: high internal consistency reliability and similar inter-item and item-scale correlations. Factor analyses revealed somewhat different structures between the two samples, but explained similar amounts of variance; regression analyses indicated that income and self-rated oral health were significant predictors of GOHAI scores in both samples. Conclusions : The GOHAI exhibits satisfactory psychometric properties in both samples and is sensitive to sociodemographic differences among and between two samples of older men. Results suggest continued use of the GOHAI as an indicator of the impact of oral conditions on functioning and well-being in a variety of samples.  相似文献   
76.
The aim of the present study was to compare the anchorage of TiO2-blasted screw and cylindrical implants with conventionally used machine-produced screw and cylindrical implants inserted immediately in extraction sockets on dogs. 6 adult mongrel dogs had 3rd and 4th mandibular premolars extracted bilaterally and 24 commercial pure titanium implants were placed immediately in extraction sockets and covered with mucoperiosteum. Each dog had inserted 4 implants: 1 screw implant and 1 cylindrical implant blasted with titanium-dioxide-particles; 1 screw implant and 1 cylindrical implant with machine-produced (m.p.) surface (controls). After a healing period of 12 weeks, 16 implants from 4 animals were used for removal torque test, which demonstrated that significantly higher removal torque force was needed to unscrew the implants blasted with titanium-dioxide-particles, than the normal m.p. implants. The medians for the TiO2-blasted screw and cylindrical implants were > 150 Ncm and 105 Ncm, respectively, while the values for the m.p. implants were 60 Ncm and 35 Ncm, respectively. The SEM investigation demonstrated a high irregularity of the TiO2-blasted surface compared to the machined surface. The Ra and Rz values for surface roughness were higher for the TiO2-blasted implants than for the normal m.p. implants. Histomorphometrically, the arithmetic mean of the direct bone-implant contact fraction was 69%. There was no significant difference in direct bone-implant contact length fraction between TiO2-blasted implants and the control implants. The implants blasted with titanium-dioxide-particles in this study showed a better anchorage than implants with a machine-produced surface. The screw implants showed a better anchorage than the cylindrical implants.  相似文献   
77.
A new phantom set, which consists of ten acrylic plate phantoms with several kinds of holes, was designed for visual detection tests of intra-oral x-ray imagin systems. Detection tests of two kinds of dental x-ray films were performed using three kinds of phantoms, an aluminum test object, Burger's phantom and the new phantom set. Detection-ability curves generated against optical density were compared. Moreover, correlation between the SNR (signal-to-noise ratio) factor and detection ability was analyzed. False positive rates were also compared. To reduce the number of phantom plate that had to be tested in the new phantom set, the number of detected signals for each phantom plate was cumulatively added and statistically compared to the total number of detected signals. The signals produced with the aluminum test object were too large. The detection ability with Burger's phantom was affected by psychological effect. The detection ability with the new phantom set was most closely correlated to the SNR. False positive rates could be compared with the new phantom set but not with the aluminum test object. The new phantom with holoes smaller than 0.6mm in diameter did not figure into the results. In conclusion, the newly designed phantom set is useful for visual detection tests of intra-oral x-ray imaging systems.  相似文献   
78.
Arrow P, Brennan D, Spencer AJ. Quality of life and psychosocial outcomes after fixed orthodontic treatment: a 17‐year observational cohort study. Community Dent Oral Epidemiol 2011; 39: 505–514. © 2011 John Wiley & Sons A/S Abstract – Background: There is little evidence to suggest that orthodontic treatment can prevent or reduce the likelihood of dental caries or of periodontal disease or dental trauma and temporomandibular disorders, but there is a modest association between the presence of malocclusion/orthodontic treatment need and quality of life. However, little is known of the long‐term outcomes of orthodontic treatment. This study reports on the longitudinal follow‐up of quality of life and psychosocial outcomes of orthodontic treatment among a cohort of adults who were examined as adolescents in 1988/1989. Materials and Methods: Children who were examined in 1988/1989 were invited to a follow‐up in 2005/2006. Respondents completed a questionnaire, which collected information on quality of life, receipt of orthodontic treatment and psychosocial factors, and were invited for a clinical examination. Oral health conditions including occlusal status using the Dental Aesthetic Index were recorded. Analysis of variance and multiple linear regression were used to examine the relationship between the measured factors. Results: There was no statistically significant association between occlusal status at adolescence and quality of life at adulthood. Those individuals who had orthodontic treatment but did not need orthodontic treatment had higher self‐esteem (23.1, SD 5.2) and were more satisfied with life (18.5, SD 3.7) than other treatment groups (self‐esteem range, 20.0–22.7; life satisfaction range, 16.4–18.1), anova P < 0.01 and P < 0.05, respectively. Occlusal status at adulthood was significantly associated with quality of life, P < 0.01. Multivariate analyses showed a statistically significant association between occlusal status at adolescence (‘Desirable treatment’β = 0.70, P = 0.04) and adulthood (‘Desirable treatment’β = 1.66, P < 0.01) with quality of life. Orthodontic treatment was negatively associated with psychosocial factors (life satisfaction; fixed orthodontic treatment (FOT) β = ?0.91, P = 0.02 and self‐esteem; FOT β = ?1.39, P < 0.01). Conclusions: Occlusal status appears to have limited association with quality of life and psychosocial factors. Receipt of fixed orthodontic treatment does not appear to be associated with oral health‐related quality of life but appears to be negatively associated with self‐esteem and satisfaction with life.  相似文献   
79.
Objectives : An epidemiologic analysis was performed to identify patient and dentist factors influencing over- and undertreatment of restorative services in a sample of insured adults. Methods : At baseline, 681 Washington State employees and their spouses, aged 20 to 34 years and residing in the Olympia or Pullman areas, were interviewed by telephone. Oral assessments were conducted to measure personal characteristics, oral disease, and restoration quality. Adults were followed for two years to measure use of restorative services from dental insurance claims. Each adult's baseline and claims data were linked with provider and practice variables collected from the dentist who provided treatment. Results : For overtreatment, 39 percent of adults received one or more replacement restorations in nondecayed teeth with satisfactory fillings at baseline, while 18 percent of adults had one or more restorations placed in teeth with no decay and fillings. An adult's probability of overtreatment was higher if the adult had more fillings at baseline, or if an adult's dentist was younger, had a busy practice, advertised, charged higher fees, had less continuing education, or had a solo practice. For undertreatment, about 16 percent of adults either received no replacement restorations in teeth with unsatisfactory fillings at baseline, or had decayed teeth at baseline that were not filled or crowned. An adult's probability of undertreatment was higher if an adult had less decayed or more missing surfaces at baseline, or if an adult's dentist believed in sharing information with patients, had a busy practice, or reported not placing fillings when radiographic evidence of new caries was present. Conclusion : A minority of adults aged 20 to 34 experienced potential over- or undertreatment of restorative services, which are influenced by both patient and dentist factors.  相似文献   
80.
Objectives: The objectives of this study is to explore the relationship between pediatric patients' orthodontic treatment need, the patients' assessments of their smile‐related quality of life (QoL), their parents' proxy assessment of their child's QoL and own assessments of their child's smile, and the patients' objectively assessed smiling patterns. Methods: Survey data were collected from 102 patients (53 boys/49 girls; age range: 9–13 years) and their parents. Orthodontic treatment need was assessed with the Index of Complexity, Outcome, and Need (ICON). Smiling patterns were determined by videotaping patients' smiles while they watched a cartoon. Thirty predetermined sections of these tapes were then assessed by two independent raters to measure the patients' smiling patterns. Results: The aesthetic component and total ICON scores correlated with the patients' smile‐related QoL (r = 0.25; P = 0.014/r = 0.23; P = 0.024), parental proxy assessments of the child's smile‐related QoL (r = 0.29; P = 0.004/r = 0.26; P = 0.009), the parents' own assessments of their child's smile (r = 0.32; P = 0.002/r = 0.29; P = 0.005), and the number of negative adjectives chosen by the parents to describe their child's smile (r = 0.32; P = 0.002/r = 0.30; P = 0.004). Although the smiling patterns were correlated with the patients' smile‐related QoL responses (height of smile: r = 0.29; P = 0.005/number of teeth shown: r = 0.30; P = 0.004), the ICON scores were not correlated with the patients' smiling patterns. Conclusions: Objectively assessed orthodontic treatment need correlates with the patients' and parents' assessments of the child's smile‐related QoL scores. However, while objective smiling patterns are related with the patients' smile‐related QoL, they are not correlated with the patients' orthodontic treatment need.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号