In situ formation of the loop snare technique for retrieval of foreign bodies from vessels

Purpose: To investigate the feasibility and effectiveness of in situ formation of the loop snare technique for retrieval of foreign bodies from vessels.Materials and methods: We retrospectively reviewed in situ formation of the loop snare technique for retrieval of foreign bodies in 6 patients. After placing the guide wire and the loop of the gooseneck snare on each side of the tubes, the soft tip of the guide wire was caught with the gooseneck snare to form a new loop structure. The foreign body was retrieved with the new loop snare by combining the gooseneck snare and the guide wire. We reviewed the application of this technique in 6 patients with fractured central venous catheters without free ends.Results: With in situ formation of the loop snare technique, the internal ruptured catheter was successfully removed from all of the 6 patients in about 2 to 4 min. There were no complications such as arrhythmia or heart valve injury in the 6 patients with the distal end of the fragment in the pulmonary artery or right atrium.Conclusion: The in situ formation loop snare technique is an effective and fast means of retrieving tubular foreign bodies without free ends from vessels. Further research is needed to investigate the practical utility of the method for retrieval of all kinds of foreign bodies.     

Three-Dimensional Echocardiography-Derived Non-Invasive Right Ventricular Pressure-Volume Analysis

In patients with pulmonary hypertension, repeated evaluations of right ventricular (RV) function are still required for clinical decision making, but the invasive nature of current pressure-volume analysis makes conducting regular follow-ups in a clinical setting infeasible. We enrolled 12 patients with pulmonary arterial hypertension (PAH) and 10 with pulmonary venous hypertension (PVH) May 2016–October 2016. All patients underwent a clinically indicated right heart catheterization (RHC), from which the yielded right ventricular pressure recordings were conjugated with RV volume by 3-D echocardiography to generate a pressure-volume loop. A continuous-wave Doppler envelope of tricuspid regurgitation was transformed into a pressure gradient recording by the simplified Bernoulli equation, and then a systolic pressure gradient-volume (PG-V) diagram was generated from similar methods. The area enclosed by the pressure-volume loop was calculated to represent semi-invasive right ventricular stroke work (RVSW_RHC). The area between the PG-V diagram and x-axis was calculated to estimate non-invasive RVSW (RVSW_echo). Patients with PAH have higher RV pressure, lower pulmonary arterial wedge pressure and larger RV volume that was contributed by the dilation of RV mid-cavity minor dimension. We found no significant difference of traditional parameters between these two groups, but RVSW values were significantly higher in PAH patients. The RVSW values of these two methods were significantly correlated by the equation RVSW_echo = 0.8447 RVSW_RHC + 129.38 (R² = 0.9151, p < 0.001). The linearity remained satisfactory in both groups. We conclude that a PG-V diagram is a reliable method to estimate RVSW and to depict pathophysiological status.     

高危型HPV联合TCT检测在宫颈病变Leep术后的应用价值

目的探讨高危型人乳头瘤病毒（high-risk human papilloma virus,HR-HPV）联合液基薄层细胞学检测（liquid-based thinprep cytology test,TCT）在宫颈上皮内瘤样病变（cervical intraepithelial neoplasia,CIN）行宫颈环形电切术（loop electrosurgical excision procedure,Leep）后的临床应用价值。方法回顾性对比分析528例患者,经术前HR-HPV、TCT检测并宫颈活检病理确诊≥CINⅠ,Leep术后接受HR-HPV联合TCT检测随访12-36个月。结果术前所有病例TCT≥ASCUS,术后3月、6月、12月、18月、24月、30月和36月随访TCT异常率分别为0.12%（1/528）、2.84%（15/528）、1.33%（7/528）、1.17%（6/528）、0.76%（4/528）、0.38%（2/528）、0%;HR-HPV阳性率分别为0%（未查）、26.89%（142/528）、19.32%（102/528）、12.12%（64/528）、6.06%（32/528）、3.60%（19/528）、2.46%（13/528）;术后病变持续或复发的23例,HR-HPV联合TCT双项检测病理诊断符合率为91.30%。结论 Leep术后HR-HPV联合TCT检测对评判手术效果及术后随访、预防宫颈病变复发具有较高的临床应用价值。     

循证护理在宫颈环状电切术治疗宫颈糜烂中的应用效果观察

目的 观察循证护理在宫颈环状电切术(LEEP)治疗宫颈糜烂中的应用效果.方法 选取2012年8月-2014年3月的非妊娠期重度宫颈糜烂患者90例,随机分为循证组48例和对照组42例.2组患者均行LEEP术,在此基础上对照组给予常规护理,循证组给予循证护理.观察2组的临床疗效及并发症、手术时间、术中出血量、创面愈合时间及患者满意度的差异.结果 2组均顺利完成手术,循证组发生术后出血2例(4.17％),对照组发生9例(21.43％),2组差异显著(P＜0.05);循证组的术中出血量及创面愈合时间均显著低于对照组(P＜0.01),患者满意率显著高于对照组(P＜0.05).结论 循证护理可显著改善LEEP术治疗重度宫颈糜烂过程中的护理质量,效果满意.     

宫颈环形电切术治疗宫颈上皮内瘤变的应用研究

目的：探讨宫颈环形电切术治疗宫颈上皮内瘤变的临床应用价值。方法选取合川区人民医院收治的宫颈上皮内瘤变患者80例作为研究对象,根据病理情况分为两组：观察组40例应用宫颈环形电切术进行治疗,对照组40例应用冷刀锥切术进行治疗。对比观察两组患者的临床疗效、术后并发症及预后复发情况。结果两组患者均顺利完成手术,无中转病例;与对照组比较,观察组患者的平均手术时间、创面愈合时间及术中出血量均明显减少,差异有统计学意义（P＜0．01）。此外,术后根据患者个体情况分别完成6个月至2年的随访,与对照组相比,观察组术后治愈率显著升高,并发症发生率和复发率显著降低,各项指标差异均有统计学意义（ P＜0．05或 P＜0．01）。结论宫颈环形电切术疗效确切、安全性高,既能降低宫颈癌的发病率,又能保留患者子宫、满足其生育要求,值得临床进一步推广应用。