Inflammatory myofibroblastic tumor of the larynx: report of a case and review of the literature

Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm, most commonly seen in children and adolescents. It can occur in nearly every part of the body. Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm mostly seen in the lungs, but also in extrapulmonary sites. But it may rarely be seen in the vical cord. We report a case of a 73-year-old men presented with hoarseness and cough. Laryngoscopy reveals a large non-ulcerated, red subepithelial mass arising from the right vical cord. Magnetic resonance imaging (MRI) scan revealed a mass in the right vical cord, and magnetic resonance imaging (MRI) enhanced scan showed the mass of the right vical cord inhomogeneous enhancement. The patient underwent right cordectomy with KTP laser, and further assessment of the tissue demonstrated a pathologic diagnosis of IMT.     

家兔喉淋巴管的微细分布

目的进一步明确家兔喉淋巴管的微细分布。方法采用5′-核苷酸酶-碱性磷酸酶双重染色法(5′-Nase-ALP),半薄切片光镜观察,超薄切片电镜观察。结果喉壁除韧带和软骨层外,其粘膜层、粘膜下层、肌层和外膜均可见毛细淋巴管和淋巴管,其分布的密度不同。喉各分区淋巴管分布具有显著差异,其中以会厌喉面分布密度最高,声襞淋巴管的分布密度最低。在喉的三个间隙即会厌前间隙、声门旁间隙和任克氏间隙中均存在淋巴管,但检出率较低。结论喉壁除韧带和软骨层外,其余各层均存在毛细淋巴管和淋巴管,喉各分区淋巴管分布密度不同。     

EGFR蛋白在喉鳞状细胞癌中的表达及临床意义

目的探讨表皮生长因子受体（epithelial growth factor receptor,EGFR）蛋白在喉鳞状细胞癌中表达的临床意义。方法应用免疫组织化学-链霉菌抗生物素蛋白-过氧化物酶连结法（streptavidin-perosidase,SP）检测58例喉鳞状细胞癌和15例正常喉黏膜标本中EGFR蛋白的表达。结果 EGFR蛋白在喉鳞状细胞癌和正常口腔黏膜标本的表达阳性率分别为72.41%和6.67%（P〈0.01）。EGFR蛋白与年龄、性别、浸润程度和淋巴结转移之间的差异无统计学意义（P〉0.05）,但是与肿瘤分期、肿瘤分化程度的差异有统计学意义（P〈0.01）。结论 EGFR可能参与喉鳞状细胞癌发生、发展,并且与喉鳞状细胞癌的分化有关,但是与浸润及转移可能无关。     

Patterns of laryngeal apraxia in two patients with Broca's aphasia

In this study the transillumination technique was applied to the study of laryngeal movements during speaking in two Broca's aphasics with apraxia of speech. In particular, laryngeal adductory and abductory gestures in the production of voiced and voiceless obstruents were analysed. The two patients presented disturbances concerning movement shape, amplitude, and timing. Patient 1 had particular problems in the initiation of laryngeal adduction. These observations are compared to the patients' clinical patterns of apraxic speech and are discussed in the light of earlier studies of apraxic speech.     

Real‐time motion correction for high‐resolution larynx imaging

Motion—both rigid‐body and nonrigid—is the main limitation to in vivo, high‐resolution larynx imaging. In this work, a new real‐time motion compensation algorithm is introduced. Navigator data are processed in real time to compute the displacement information, and projections are corrected using phase modulation in k‐space. Upon automatic feedback, the system immediately reacquires the data most heavily corrupted by nonrigid motion, i.e., the data whose corresponding projections could not be properly corrected. This algorithm overcomes the shortcomings of the so‐called diminishing variance algorithm by combining it with navigator‐based rigid‐body motion correction. Because rigid‐body motion correction is performed first, continual bulk motion no longer impedes nor prevents the convergence of the algorithm. Phantom experiments show that the algorithm properly corrects for translations and reacquires data corrupted by nonrigid motion. Larynx imaging was performed on healthy volunteers, and substantial reduction of motion artifacts caused by bulk shift, swallowing, and coughing was achieved. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.