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991.
Veronica P.Y. Kwok Tianfu Wang Siping Chen Kofi Yakpo Linlin Zhu Peter T. Fox Li Hai Tan 《Human brain mapping》2015,36(1):304-312
Research on how lexical tone is neuroanatomically represented in the human brain is central to our understanding of cortical regions subserving language. Past studies have exclusively focused on tone perception of the spoken language, and little is known as to the lexical tone processing in reading visual words and its associated brain mechanisms. In this study, we performed two experiments to identify neural substrates in Chinese tone reading. First, we used a tone judgment paradigm to investigate tone processing of visually presented Chinese characters. We found that, relative to baseline, tone perception of printed Chinese characters were mediated by strong brain activation in bilateral frontal regions, left inferior parietal lobule, left posterior middle/medial temporal gyrus, left inferior temporal region, bilateral visual systems, and cerebellum. Surprisingly, no activation was found in superior temporal regions, brain sites well known for speech tone processing. In activation likelihood estimation (ALE) meta‐analysis to combine results of relevant published studies, we attempted to elucidate whether the left temporal cortex activities identified in Experiment one is consistent with those found in previous studies of auditory lexical tone perception. ALE results showed that only the left superior temporal gyrus and putamen were critical in auditory lexical tone processing. These findings suggest that activation in the superior temporal cortex associated with lexical tone perception is modality‐dependent. Hum Brain Mapp, 36:304–312, 2015. © 2014 Wiley Periodicals, Inc . 相似文献
992.
Establishing and maintaining reference is a crucial part of discourse. In spoken languages, differential linguistic devices mark referents occurring in different referential contexts, that is, introduction, maintenance, and re-introduction contexts. Speakers using gestures as well as users of sign languages have also been shown to mark referents differentially depending on the referential context. This article investigates the modality-specific contribution of the visual modality in marking referential context by providing a direct comparison between sign language (German Sign Language; DGS) and co-speech gesture with speech (German) in elicited narratives. Across all forms of expression, we find that referents in subject position are referred to with more marking material in re-introduction contexts compared to maintenance contexts. Furthermore, we find that spatial modification is used as a modality-specific strategy in both DGS and German co-speech gesture, and that the configuration of referent locations in sign space and gesture space corresponds in an iconic and consistent way to the locations of referents in the narrated event. However, we find that spatial modification is used in different ways for marking re-introduction and maintenance contexts in DGS and German co-speech gesture. The findings are discussed in relation to the unique contribution of the visual modality to reference tracking in discourse when it is used in a unimodal system with full linguistic structure (i.e., as in sign) versus in a bimodal system that is a composite of speech and gesture. 相似文献
993.
Takeharu KUNIEDA Yukihiro YAMAO Takayuki KIKUCHI Riki MATSUMOTO 《Neurologia medico-chirurgica》2015,55(5):374-382
There has been a paradigm shift in the understanding of brain function. The intrinsic architecture of neuronal connections forms a key component of the cortical organization in our brain. Many imaging studies, such as noninvasive magnetic resonance imaging (MRI) studies, have now enabled visualization of the white matter fiber tracts interconnecting the functional cortical areas in the living brain. Although such a structural connectome is essential for understanding of cortical function, the anatomical information alone is not sufficient. Practically, few techniques allow the investigation of the excitatory and inhibitory mechanisms of the cortex in vivo in humans. Several attempts have been made to track neuronal connectivity by applying direct electrical stimuli to the brain in order to stimulate subdural and/or depth electrodes and record responses from the functionally connected cortex. In vivo single-pulse electrical stimulation (SPES) and/or cortico-cortical evoked potential (CCEP) were recently introduced to track various brain networks. This article reviews the concepts, significance, methods, mechanisms, limitations, and clinical applications of CCEP in the analysis of these dynamic connections. 相似文献
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Elizabeth Hampson 《Laterality》2016,21(4-6):415-432
ABSTRACTPeople with congenital adrenal hyperplasia (CAH) are exposed to elevated levels of androgens in utero due to overproduction by the adrenal cortex. In order to test whether high levels of prenatal androgens influence the development of handedness preferences and left-hemisphere language representation, we studied 39 patients with CAH (28 females, 11 males) and 25 unaffected sibling controls (17 females, 8 males). Hand preference for 15 unimanual activities was evaluated via questionnaire and pantomime, and a consonant–vowel dichotic listening test was administered. Contemporary theories disagree as to whether high testosterone is said to increase or decrease the probability of developing a typical right-hand preference. Results showed no significant differences on the handedness inventory. Relative to controls, however, patients with CAH showed a significantly larger right-ear advantage on the dichotic syllables task, indicating stronger left-hemisphere lateralization of language. These results support an emerging body of evidence suggesting that high testosterone may bias lateralized development toward the population norm, but run counter to the Geschwind–Behan–Galaburda model which associates high prenatal testosterone with a greater prevalence of left-handedness. 相似文献
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Carmen Julia Coloma Claudia Araya Camilo Quezada Maria Mercedes Pavez Mariangela Maggiolo 《Clinical linguistics & phonetics》2016,30(9):649-662
This study examined grammaticality and complexity of sentences in monolingual Spanish-speaking children with specific language impairment (SLI). A group of SLI children (n = 13), mean age 6, was compared to a control group (CCG) matched by age (n = 11), and a younger control group (LCG) with similar linguistic development (n = 13). Grammaticality and complexity of sentences were analysed including identification and counting of: a) simple and complex sentences, b) grammatical and ungrammatical sentences, and c) types of grammatical errors. SLI children were found to be more ungrammatical than CCG in both simple and complex sentences. Considering the number of errors in all sentences produced, SLI children commit more errors than both control groups. Complexity of sentences did not show statistical differences among groups. Future research should explore in further detail the types of errors made by monolingual Spanish-speaking SLI children. 相似文献
1000.
Maria Teresa Guasti Silvia Palma Elisabetta Genovese Paolo Stagi Gabriella Saladini Fabrizio Arosio 《Clinical linguistics & phonetics》2016,30(9):663-678
Third-person direct object (DO) clitic pronoun production is examined through an elicited production method in pre-school– and primary school–aged groups of Italian children with specific language impairment (SLI) to establish whether there is an improvement from age 5 years to age 7 years and whether there are qualitative differences in the two groups’ responses. It was found that 5- and 7-year-old Italian children with SLI produce fewer third-person DO clitics than same-age peers. The kind of responses they provide changes: at 5 years, children with SLI tend to omit clitics, while at 7 years, they use a full noun. Production of third-person DO clitics is a persistent challenge for children with SLI and is confirmed to be a good clinical marker both at 5 and 7 years of age. 相似文献