Correlation of Breast Cancer Incidence with the Number of Motor Vehicles and Consumption of Gasoline in Korea

While several reproductive and lifestyle-related factors are already well-known as established risk factorsfor breast cancer, environmental factors have attracted attention only recently. The objective of the currentstudy was to assess the association between the breast cancer incidences in females, the mortality rate and thenumber of motor vehicles on the one side and the consumption of gasoline which could work as a major sourceof air pollution at the other side. The breast cancer incidences and the mortality trends were compared withvarious indices of westernization like dietary patterns or industrialization with 10 years lag of time. Geographicalvariations with 10, 15 and 20 years lag of time were assessed between the breast cancer incidence in 2010and the number of motor vehicles as well as the consumption of gasoline. The upward trend of motor vehiclenumbers proved to be comparable to those of breast cancer incidence and mortality. However, the consumptionof gasoline started to decrease since the mid-1990s. The geographic distribution of motor vehicle numbers andgasoline consumption in 1990 is in a positive correlation with the breast cancer incidence rates in 2010 and the20-year lag time (R2 0.379 with the number of motor vehicles and 0.345 with consumption of gasoline). In a linearrelationship between the breast cancer incidences in 2010 and the log transformed number of motor vehicles, thelog transformed consumption of gasoline in 2000 also showed a positive relationship (R2 0.367 with the numberof motor vehicles and 0.329 with consumption of gasoline). The results of the current study indicate that theremay be a positive relation between the number of vehicles, gasoline consumption and the incidence of breastcancer from the aspects of long-term trends and geographical variation.     

溶济汽油对作业工人皮肤的影响及作用机制探索

研究溶剂汽油对职业人群的皮肤损害作用及机制。方法采用１∶１配对调查方法和高效薄层层析技术，对溶剂汽油接触组与对照组各５２名工人的皮肤健康状况和皮脂成分进行了研究。结果接触组皮肤光泽度、弹性明显下降，皮肤角化度、皮肤干燥程度及指甲异常率均显著高于对照组（Ｐ＜０．０５），其中以皮肤皲裂、脆甲最为常见。接触组皮脂中神经酰胺、游离脂肪酸及胆固醇的含量均显著低于对照组（Ｐ＜０．０５）。结论皮肤长期接触溶剂汽油，对皮肤与指甲有损害作用，其作用机制与溶剂汽油致使皮脂降低有关。     

硬脂酸与溶剂汽油用于病理制片的临床应用

目的消除二甲苯对人体的毒害作用,改善病理工作者的工作环境,预防职业病的发生。方法应用硬脂酸与溶剂汽油替代二甲苯用于病理石蜡制片。结果所有活体组织的HE染色、各种组织化学染色和免疫组织化学染色均获得满意效果。结论硬脂酸与溶剂汽油可以取代二甲苯用于病理石蜡制片。     

两群替代微粒群优化算法及其应用

提出一种两群替代微粒群优化算法（TSSPSO），并对算法参数进行分析和对算法方程进行修正。该方法将微粒分成飞行方向不同的两分群，其中一分群微粒朝着最优微粒飞行，另一分群微粒朝着相反方向飞行；飞行时，每一微粒不仅受到微粒本身飞行经验和本分群最优微粒的影响，还受到全群最优微粒的影响。搜索时，每一次迭代均以一定的替代率用一分群中若干优势微粒取代另一分群中相同数目的劣势微粒。对4种常用函数的优化问题进行测试并进行比较，结果表明：两群替代微粒群优化算法比基本微粒群优化算法更容易找到全局最优解，优化效率和优化性能明显提高。将两群替代微粒群优化算法用于常压塔汽油干点软测量，建立基于两群替代微粒群优化算法的汽油干点神经网络软测量模型，通过与实际工业数据的比较，表明基于两群替代微粒群神经网络的软测量模型精度高、性能好。     

溶剂汽油对大鼠皮肤皮脂成分的影响

研究溶剂汽油对大鼠皮肤皮脂成分的影响。「方法」４５只Ｗｉｓｔａｒ雄性大鼠分为组、实验组和干预组,染毒方式为经皮染毒。实验组染毒剂量分别为：２５０ｍｇ／ｃｍ＾２＊１ｄ,２５０ｍｇ／ｃｍ＾２＊４ｄ,２５０ｍｇ／ｃｍ＾２＊８ｄ,染毒面积为２＊３ｃｍ＾２。干预组则是涂主护剂后,再进行染毒,染毒剂量２５０ｍｇ／ｃｍ＾２＊８ｄ。染毒结束后,分离染毒部位皮肤,采用高效薄层层析法（ＨＰＴＬＣ）测定皮脂。「结果」各