全文获取类型
收费全文 | 48556篇 |
免费 | 3501篇 |
国内免费 | 1369篇 |
专业分类
耳鼻咽喉 | 378篇 |
儿科学 | 1665篇 |
妇产科学 | 1668篇 |
基础医学 | 5166篇 |
口腔科学 | 1150篇 |
临床医学 | 7551篇 |
内科学 | 5922篇 |
皮肤病学 | 598篇 |
神经病学 | 2207篇 |
特种医学 | 2311篇 |
外国民族医学 | 20篇 |
外科学 | 3347篇 |
综合类 | 10441篇 |
现状与发展 | 11篇 |
一般理论 | 2篇 |
预防医学 | 3162篇 |
眼科学 | 976篇 |
药学 | 2117篇 |
78篇 | |
中国医学 | 1191篇 |
肿瘤学 | 3465篇 |
出版年
2024年 | 124篇 |
2023年 | 645篇 |
2022年 | 1346篇 |
2021年 | 1879篇 |
2020年 | 2017篇 |
2019年 | 1446篇 |
2018年 | 1415篇 |
2017年 | 1457篇 |
2016年 | 1802篇 |
2015年 | 1591篇 |
2014年 | 2980篇 |
2013年 | 3128篇 |
2012年 | 2724篇 |
2011年 | 2929篇 |
2010年 | 2380篇 |
2009年 | 2342篇 |
2008年 | 2295篇 |
2007年 | 2538篇 |
2006年 | 2381篇 |
2005年 | 2085篇 |
2004年 | 1906篇 |
2003年 | 1650篇 |
2002年 | 1351篇 |
2001年 | 1230篇 |
2000年 | 935篇 |
1999年 | 805篇 |
1998年 | 667篇 |
1997年 | 665篇 |
1996年 | 604篇 |
1995年 | 528篇 |
1994年 | 473篇 |
1993年 | 428篇 |
1992年 | 346篇 |
1991年 | 327篇 |
1990年 | 289篇 |
1989年 | 233篇 |
1988年 | 274篇 |
1987年 | 223篇 |
1986年 | 175篇 |
1985年 | 178篇 |
1984年 | 112篇 |
1983年 | 74篇 |
1982年 | 87篇 |
1981年 | 76篇 |
1980年 | 73篇 |
1979年 | 62篇 |
1978年 | 40篇 |
1977年 | 23篇 |
1976年 | 27篇 |
1975年 | 27篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
H. Wessling C. L. Simosono M. Escosa-Bagé P. de las Heras-Echeverría 《Acta neurochirurgica》2006,148(6):673-675
Summary We present a case of blindness and Anton’s syndrome in a psychiatric patient with late diagnosis of a giant frontal meningioma.
The criteria for advanced diagnostic imaging in the psychiatric population are discussed. We conclude that MR or CT scan is
indicated in psychiatric in-patients who fail to improve with standard psychiatric treatment. This strategy should be submitted
to a cost-benefit analysis. 相似文献
52.
Intraductal papillary mucinous tumor (IPMT) of the pancreas is characterized by slow growth and a relatively favorable prognosis, however, invasive cancer originating in an IPMT is associated with a poor prognosis. Although various parameters in imaging modalities have been advocated to differentiate between benign IPMN and malignant ones, it is not easy to obtain definite diagnosis based on these parameters. Peroral pancreatoscopy (POPS) allows a clear and direct visualization of the pancreatic duct, providing useful information regarding tumor nature in IPMT. The authors have studied the usefulness of POPS in the diagnosis of IPMT. Nevertheless, its usefulness is not necessarily widely accepted and the significance of POPS is still controversial. In this review, the authors intended to address the diagnostic value of POPS and to clarify its role in the diagnosis of IPMT. The authors think treatment of IPMT can be improved by introducing POPS because the determination of surgical procedure as well as the area of resection based on the preoperative diagnosis of the involvement of the main pancreatic duct and branch duct is inevitable. 相似文献
53.
54.
Maria Stella Aniello Davide Martino Gianluca Masi Paolo Livrea Giovanni Defazio 《Movement disorders》2006,21(4):571-575
We developed a self-administered questionnaire for screening the most common adult-onset dystonias. It was tested in 90 first-degree relatives of 22 adult-onset dystonia patients, yielding 79% sensitivity and 94% specificity. Simulation of a case-finding procedure based on serial application of the questionnaire and clinical examination of both subjects screening positive and subjects screening negative who had < 8 years of schooling increased sensitivity to 95% and specificity to 100%. This questionnaire may be an important screening resource for familial aggregation studies to be used in the context of a complex case-finding procedure. 相似文献
55.
Michele D. Mignogna Stefano Fedele Lucio Lo Russo Lorenzo Lo Muzio 《Journal of oral pathology & medicine》2003,32(4):200-205
BACKGROUND: The recurrent chronic orofacial swelling caused by orofacial granulomatosis (OFG) can cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. Although the enlargement of the lips is described to be the most common presenting complaint, the clinical onset of OFG may be characterized by minor associated mucosal and neurological manifestations, making early diagnosis very difficult or, sometimes, merely presumable. PATIENTS AND METHODS: We retrospectively analyzed the clinical manifestations of 19 patients with OFG, who were examined at our institution between 1998 and 2002, in order to determine their initial manifestations and presenting symptoms. RESULTS: A total of 10 patients showed classical recurrent enlargement of the lips (six lower; four upper) as presenting symptom. In the other nine patients, OFG onset was characterized by transient unilateral facial nerve palsy (two cases), intraoral manifestations (two cases), recurrent swelling of the periorbital area (two cases), of the chin (one case), of the zygomatic area (one case), and of the cheeks (one case). CONCLUSION: Our data underlined that OFG onset could be frequently characterized by widely variable, multiform, and temporary clinical findings. Involvement of atypical sites of the orofacial region and presence of single minor manifestations may occur as presenting symptoms, often preceding the development of traditional clinical findings. 相似文献
56.
目的 探讨创伤性、迟发性颅内血肿的早期诊断和治疗的临床效果。方法 对22例病人的发病年龄、性别、伤因、早期诊断和治疗效果进行了回顾性分析。经过2—6个月,按GOS评定治疗效果。结果 良好者12例,中残者5例,重残者1例,植物生存者1例,死亡者3例,死亡率为14%。结论 早期诊断和治疗本病对于提高治愈率和降低死亡率至关重要,早期手术治疗本病,乃是多数病人首选的治疗方法。 相似文献
57.
Primary malignant melanoma of the bladder 总被引:1,自引:0,他引:1
MAURO PACELLA FABRIZIO GALLO CHRISTIAN GASTALDI CARLO AMBRUOSI GIORGIO CARMIGNANI 《International journal of urology》2006,13(5):635-637
Primary malignant melanomma of bladder is extremely rare: 18 cases are reported to date. An 82 year-old man underwent trans-urethral resection of bladder for a bleeding tumor of the posterior wall. Histological diagnosis was melanoma of the bladder. There was no history of previous or regressed cutaneous malignant melanoma. Margins of the bladder lesion contained atypical melanocytes similar to those commonly seen in the periphery of primary mucous membrane lesions. Clinical studies and radiological examinations were negative for other primary site of melanoma. The patient had a bladder recurrence that was consistent with primary tumor and died of widespread disease 9 months after diagnosis. 相似文献
58.
R. MOSZYNSKI D. SZPUREK A. SMOLEN† & S. SAJDAK 《International journal of gynecological cancer》2006,16(1):45-51
The purpose of this study was to compare prognostic models evaluating the probability of an ovarian cancer occurrence based on a number of clinical and ultrasonographic data in women with adnexal masses. A total of 686 women with adnexal masses underwent the examinations between 1994 and 2002. The recorded parameters included: age, menopausal status, body mass index, the grayscale and Doppler ultrasonographic examination, and selected markers concentration levels. In order to find the best combination of features, which significantly influences the probability of malignancy, stepwise logistic regression analysis, as well as artificial neural network, was used. The diagnostic efficiency of received models was estimated and compared using receiver-operating characteristics (ROC) curve. The results indicate that 431 and 255 patients had a benign and malignant ovarian tumor, respectively. Application of stepwise logistic regression analysis revealed statistically significant importance of eight features. The sensitivity and specificity for the received model were 65.71% and 77.59%, respectively. Three-layer perceptron network shows 13 features as significant predictors of malignancy. The network gave a sensitivity of 85.7% and specificity of 93.1%. Comparison of area under ROC curve for received models was 0.9679 vs 0.9716. Prognostic values of the analyzed neural model are not optimal but seem to surpass logistic regression model in terms of the predictive possibilities. 相似文献
59.
J. M. Troyano M. T. Clavijo A. Gonzalez-Lorenzo I. Martí nez-Wallin O. Y. Marco P. S. Casas L. Martí nez-Cort s L. T. Merc J. Bajo-Arenas N. Hernandez D. Castro 《The Ultrasound Review of Obstetrics & Gynecology》2006,6(1):79-99
In order to assess the state and pathology of the woman's pelvis minor, a number of methods are commonly used among practitioners, encompassing clinical exploration, radiology, MRN, urodynamics, endoscopy and echography.
Echography has been poorly used in clinical pelvic exploration and its reliability is actually a matter of controversy 1. However, echographic surveys can provide us with valuable gynecological data on the state and pathologies of the soft pelvis, within the genital regions or even going beyond them, i.e. the rectal channel, bladder, urethra, anus, vascular plexuses, and all of their supporting tissues.
At our research unit, we have been employing Transvaginal Ultrasound echography (TVU) for a long time in conjunction with other pelvis-focused methods in order to study different kinds of pelvic alterations. TVU has proven to be friendly to use, fast, harmless and inexpensive, allowing serial explorations and producing high-quality dynamic images (loop-cinema, video-tape). Furthermore, this method is fairly aseptic in that the occurrence of faeces in the rectal ampolla is not a nuisance but a bonus in tracking the contours of the rectum walls and other topographical features which would be otherwise difficult to survey.
A complete pelvic floor TVU may add no longer than 5-8 minutes to a routine gynecological examination, can be implemented by the general gynecologist and generates data that can be further studied by the appropriate specialist for a more insightful evaluation 2. 相似文献
Echography has been poorly used in clinical pelvic exploration and its reliability is actually a matter of controversy 1. However, echographic surveys can provide us with valuable gynecological data on the state and pathologies of the soft pelvis, within the genital regions or even going beyond them, i.e. the rectal channel, bladder, urethra, anus, vascular plexuses, and all of their supporting tissues.
At our research unit, we have been employing Transvaginal Ultrasound echography (TVU) for a long time in conjunction with other pelvis-focused methods in order to study different kinds of pelvic alterations. TVU has proven to be friendly to use, fast, harmless and inexpensive, allowing serial explorations and producing high-quality dynamic images (loop-cinema, video-tape). Furthermore, this method is fairly aseptic in that the occurrence of faeces in the rectal ampolla is not a nuisance but a bonus in tracking the contours of the rectum walls and other topographical features which would be otherwise difficult to survey.
A complete pelvic floor TVU may add no longer than 5-8 minutes to a routine gynecological examination, can be implemented by the general gynecologist and generates data that can be further studied by the appropriate specialist for a more insightful evaluation 2. 相似文献
60.
Thomas James Zirpoli Patricia Mulhearn Blasco 《Journal of developmental and physical disabilities》1988,1(1):69-77
Current medical procedures used in prenatal screening and diagnosis of handicapping conditions are reviewed. These strategies include ultrasound, amniocentesis, chorionic villus biopsy, restriction enzyme analysis, maternal serum analysis, fetoscopy, and fetal serum analysis. Along with an explanation of each method, advantages, disadvantages, and risks involved with each are provided. An understanding of these procedures by medical and educational personnel is encouraged, and the potential benefits of prenatal identification of handicapping conditions are emphasized. 相似文献