全文获取类型
收费全文 | 7446篇 |
免费 | 804篇 |
国内免费 | 41篇 |
专业分类
耳鼻咽喉 | 33篇 |
儿科学 | 2130篇 |
妇产科学 | 53篇 |
基础医学 | 759篇 |
口腔科学 | 249篇 |
临床医学 | 416篇 |
内科学 | 871篇 |
皮肤病学 | 128篇 |
神经病学 | 806篇 |
特种医学 | 44篇 |
外科学 | 182篇 |
综合类 | 204篇 |
现状与发展 | 3篇 |
一般理论 | 1篇 |
预防医学 | 1424篇 |
眼科学 | 92篇 |
药学 | 131篇 |
2篇 | |
中国医学 | 34篇 |
肿瘤学 | 729篇 |
出版年
2024年 | 36篇 |
2023年 | 178篇 |
2022年 | 208篇 |
2021年 | 294篇 |
2020年 | 333篇 |
2019年 | 381篇 |
2018年 | 347篇 |
2017年 | 302篇 |
2016年 | 297篇 |
2015年 | 266篇 |
2014年 | 400篇 |
2013年 | 605篇 |
2012年 | 418篇 |
2011年 | 305篇 |
2010年 | 265篇 |
2009年 | 277篇 |
2008年 | 309篇 |
2007年 | 262篇 |
2006年 | 264篇 |
2005年 | 229篇 |
2004年 | 223篇 |
2003年 | 199篇 |
2002年 | 196篇 |
2001年 | 156篇 |
2000年 | 160篇 |
1999年 | 124篇 |
1998年 | 126篇 |
1997年 | 132篇 |
1996年 | 123篇 |
1995年 | 92篇 |
1994年 | 87篇 |
1993年 | 95篇 |
1992年 | 60篇 |
1991年 | 67篇 |
1990年 | 42篇 |
1989年 | 60篇 |
1988年 | 48篇 |
1987年 | 44篇 |
1986年 | 37篇 |
1985年 | 33篇 |
1984年 | 30篇 |
1983年 | 18篇 |
1982年 | 33篇 |
1981年 | 28篇 |
1980年 | 18篇 |
1979年 | 24篇 |
1978年 | 17篇 |
1977年 | 9篇 |
1976年 | 14篇 |
1975年 | 9篇 |
排序方式: 共有8291条查询结果,搜索用时 15 毫秒
71.
The prevalence of respiratory symptoms and asthma among school children in three different areas of Norway 总被引:1,自引:0,他引:1
Wenche Nystad Per Magnus Ola Røksund Bjørn Svidal Øystein Hetlevik 《Pediatric allergy and immunology》1997,8(1):35-40
The role of exposure to ambient air pollution has been a topic of interest as a potential risk factor for respiratory symptoms and asthma. We expected that the prevalence rates would vary in Norway between the capital, Oslo, the mountainous area Hallingdal and the industrial area Odda. Surveys were conducted in school children, aged 6-16 years, in; Oslo (n=2577), Hallingdal (n=1177) and Odda (n=831). The parent-reported prevalence of wheeze in past year was almost similar in Oslo (13. 1 (95% CI 11. 7-14. 5)) and Upper Hallingdal (14. 2 (13. 1–15. 3)), but lower in Odda (9. 0 (7. 0–11. 0)). The findings for severe respiratory symptoms were almost equal. The age patters within each area differed. The risk of wheeze ever (p < 0.001) and wheeze in past year (p=0.04) decreased with increasing age in Odda, while there was an increase in the risk of exercise induced wheeze in Oslo (p=0.02) and Hallingdal (p < 0.001). The lifetime prevalence of asthma was lowest in Odda (5. 4 (3. 8–7. 0)) compared to Oslo (9. 4 (8. 2–10. 6)) and Hallingdal (8. 5 (6. 8–10. 2)). There was a positive association between physical activity and wheeze in past year. The results do not support the hypothesis that respiratory morbidity is more common in urban than rural areas, age and physical activity can influence the prevalence rates of respiratory symptoms in school children. 相似文献
72.
Aydan Kansu Nurten Girgin Cihan YurdaydN HÜLya Cetinkaya ÖZden Uzunalimoglu 《Pediatrics international》1998,40(6):612-615
Chronic pancreatitis is a rare disease in children and is usually secondary to underlying diseases such as hereditary pancreatitis, cystic fibrosis, hyperlipidemia, prolonged malnutrition, gallstones or anomalies of the biliary-pancreatic duct system. Hereditary pancreatitis is a common cause of chronic pancreatitis in children but is often unrecognized until months or years later. We report here a family with hereditary pancreatitis in which four members are affected. 相似文献
73.
Salbutamol or mist in acute bronchiolitis 总被引:1,自引:0,他引:1
Demet Can GÜLten Nan GÜRol Yendur Resmiye Oral Lker GÜNay 《Pediatrics international》1998,40(3):252-255
Abstract Background : The role of bronchodilators in the treatment of bronchiolitis remains controversial.
Methods : A double-blind, placebo controlled trial was performed to evaluate the clinical response to nebulized salbutamol. One hundred and fifty-six infants aged between 7 weeks and 24 months who had had an episode of wheezing and other signs and symptoms of bronchiolitis were randomized to three groups as follows: (i) nebulized salbutamol was administered to 52 patients in group I at a dose of 0.15 mg/kg in 2 mL saline; (ii) saline was nebulized to 52 patients in group II and (iii) in group III 52 patients received mist in a tent. All three groups were administered oxygen during the procedures. Treatment was repeated with the same agent after 30 min if the respiratory score was 5 or more. Respiratory rate, heart rate, oxygen saturation and presence of cyanosis, wheezing, retractions were recorded before and after each treatment.
Results : The decrease in the respiratory score was 5.2 ± 1.8, 0.82 ± 2.4 and 1.7 ± 1.3 in group I, II and III, respectively. The decrease in group I was significantly higher than in the other groups. Heart rate was similar between groups. Oxygen saturation decreased in group I without reaching statistical significance.
Conclusions: Salbutamol was shown to be effective and safe in the treatment of acute bronchiolitis. 相似文献
Methods : A double-blind, placebo controlled trial was performed to evaluate the clinical response to nebulized salbutamol. One hundred and fifty-six infants aged between 7 weeks and 24 months who had had an episode of wheezing and other signs and symptoms of bronchiolitis were randomized to three groups as follows: (i) nebulized salbutamol was administered to 52 patients in group I at a dose of 0.15 mg/kg in 2 mL saline; (ii) saline was nebulized to 52 patients in group II and (iii) in group III 52 patients received mist in a tent. All three groups were administered oxygen during the procedures. Treatment was repeated with the same agent after 30 min if the respiratory score was 5 or more. Respiratory rate, heart rate, oxygen saturation and presence of cyanosis, wheezing, retractions were recorded before and after each treatment.
Results : The decrease in the respiratory score was 5.2 ± 1.8, 0.82 ± 2.4 and 1.7 ± 1.3 in group I, II and III, respectively. The decrease in group I was significantly higher than in the other groups. Heart rate was similar between groups. Oxygen saturation decreased in group I without reaching statistical significance.
Conclusions: Salbutamol was shown to be effective and safe in the treatment of acute bronchiolitis. 相似文献
74.
The relationship of serum-eosinophil cationic protein and eosinophil count to disease activity in children with bronchial asthma 总被引:1,自引:0,他引:1
75.
76.
Teachers for the twenty-first century for the global world need to be proficient in technology and skilled as reflective practitioners. They need to be able to reflect on diversity in myriad ways: learning styles, special needs, cultural differences, racial differences, developmentally appropriate differences, teaching styles and personality differences of children, teachers, parents, community members and administrators. The paradigni shift of the twenty-first century is that teachers need to be team players who are skilled at operating in a variety of collaborative partnerships.
The Early Childhood Program Faculty, at NEIU, with the help of a Teacher Quality Education grant, developed with six universities in Illinois called Illinois Professionals Learning Partnerships (IPLP), set out to adapt the NEIU/ECED program for the twenty-first century in a global world by focusing on four goals: (1) increasing technology and writing skills across the curriculum, (2) developing reflective skills and understanding of diversity (special needs, multicultural/international cultures), (3) developing student experience working in collaborative partnerships and (4) increasing clinical experiences.
The IPLP grant enabled the ECED program to: (1) spend intensive time on changing the curriculum in two retreats a year, (2) develop a faculty cohort including tenure track faculty, visiting lecturers and adjuncts, (3) develop a combined program of research and program development, (4) recruit and hire three new tenure track international faculty, (5) develop professional development schools and intensive field experiences, (6) combine resources for many grants, (7) develop short-term international experiences and faculty exchange programs and (8) increase technology skills of students and faculty through action laboratories on using video technology, digital cameras, reflective email discussions and videography. 相似文献
The Early Childhood Program Faculty, at NEIU, with the help of a Teacher Quality Education grant, developed with six universities in Illinois called Illinois Professionals Learning Partnerships (IPLP), set out to adapt the NEIU/ECED program for the twenty-first century in a global world by focusing on four goals: (1) increasing technology and writing skills across the curriculum, (2) developing reflective skills and understanding of diversity (special needs, multicultural/international cultures), (3) developing student experience working in collaborative partnerships and (4) increasing clinical experiences.
The IPLP grant enabled the ECED program to: (1) spend intensive time on changing the curriculum in two retreats a year, (2) develop a faculty cohort including tenure track faculty, visiting lecturers and adjuncts, (3) develop a combined program of research and program development, (4) recruit and hire three new tenure track international faculty, (5) develop professional development schools and intensive field experiences, (6) combine resources for many grants, (7) develop short-term international experiences and faculty exchange programs and (8) increase technology skills of students and faculty through action laboratories on using video technology, digital cameras, reflective email discussions and videography. 相似文献
77.
Victoria Whitington Anne Glover Felicity Harley 《Early child development and care》2004,174(4):321-337
Lecturer feedback on students' essays is important to the quality of the experience students have at university (Norton & Norton, 2001). The aim of the present study was to investigate whether early childhood students at one university actually read lecturer feedback on their essays and, if they did, what they found helpful and not helpful to their learning. Feedback was defined as 'giving students information on how well or how poorly they are doing in their academic work' (Hounsell, 1987, p. 109). Using the Vygotskian concept of learning as a socially shared activity, qualitative data were collected from second-year students from a four-year early childhood degree programme via an anonymous survey and four focus groups. Major findings were that, in contrast with studies of students in other programmes, early childhood students read lecturer feedback on their essays and used feedback that was detailed and explanatory as a learning tool. Types of feedback students found to be most and least useful were identified. 相似文献
78.
Fibrocartilaginous embolus causing acute spinal cord infarction is a rare cause of acute-onset paraplegia or quadriplegia.
Few cases of survivors have been reported in the neurosurgical literature, with most reports involving post-mortem or biopsy
findings. There is little information on MRI findings in such patients. We present the youngest patient ever reported, and
discuss the important differences between fibrocartilaginous embolus and acute myelitis of childhood. A 6-year-old girl with
a history of back pain presented with sudden-onset nontraumatic paraplegia, with a clinical anterior spinal artery syndrome.
Initial MRI scan revealed intervertebral disc disease at L1–2 and an incidental thoracic syrinx, but no cause for her acute-onset
paraplegia was identified. Cerebrospinal fluid and other investigations were all negative. Sequential MRI scans revealed development
of spinal cord expansion from T10 to the conus medullaris, with increased cord signal in the anterior aspect of the spinal
cord. The intervertebral disc disease was unchanged. The imaging and clinical findings were caused by fibrocartilaginous embolus,
which meant there was no need for spinal cord biopsy. The report describes the clinical and imaging criteria for diagnosis
of fibrocartilaginous embolus, highlighting the case for avoiding an unnecessary biopsy. The clinical pattern in the paediatric
group is discussed, with features differentiating it from acute myelitis of childhood.
Received: 4 January 2000 相似文献
79.
80.
Janez Jazbec Lidija Kitanovski Richard Aplenc Maru a Debeljak Vita Dol an 《Leukemia & lymphoma》2005,46(6):893-897
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been associated not only with the risk for acute lymphoblastic leukemia (ALL) in adults and children, but also with increased methotrexate toxicity. The present study aimed to investigate whether MTHFR polymorphisms modify the risk for development of secondary malignancies in children treated for ALL with protocols that included high-dose methotrexate. MTHFR genotypes were determined in DNA samples isolated from archived bone marrow smears of 15 patients with a second malignancy and a matched control group of 30 patients who did not developed a second malignancy after the treatment for ALL. The frequencies of MTHFR C677T and A1298C genotypes in all patients were: C677T: CC 40%, CT 46.7% and TT 13.3% and A1298C: AA 46.7%, AC 44.4% and CC 8.9%. The relative risk for second malignancy was not significantly increased in ALL patients having at least one polymorphic C667T [odds ratio (OR) 1.51; 95% confidence interval (CI) 0.43 - 5.31] or one polymorphic A1298C allele (OR 1; 95% CI 0.29 - 3.46). Our study suggests that MTHFR polymorphisms are not associated with increased risk of second cancer in children treated with high-dose methotrexate. 相似文献