全文获取类型
收费全文 | 4629篇 |
免费 | 519篇 |
国内免费 | 90篇 |
专业分类
耳鼻咽喉 | 75篇 |
儿科学 | 53篇 |
妇产科学 | 626篇 |
基础医学 | 490篇 |
口腔科学 | 181篇 |
临床医学 | 460篇 |
内科学 | 390篇 |
皮肤病学 | 39篇 |
神经病学 | 122篇 |
特种医学 | 215篇 |
外国民族医学 | 1篇 |
外科学 | 1046篇 |
综合类 | 512篇 |
现状与发展 | 1篇 |
一般理论 | 8篇 |
预防医学 | 510篇 |
眼科学 | 96篇 |
药学 | 207篇 |
2篇 | |
中国医学 | 58篇 |
肿瘤学 | 146篇 |
出版年
2024年 | 13篇 |
2023年 | 68篇 |
2022年 | 132篇 |
2021年 | 204篇 |
2020年 | 196篇 |
2019年 | 255篇 |
2018年 | 228篇 |
2017年 | 236篇 |
2016年 | 224篇 |
2015年 | 201篇 |
2014年 | 319篇 |
2013年 | 383篇 |
2012年 | 245篇 |
2011年 | 300篇 |
2010年 | 200篇 |
2009年 | 203篇 |
2008年 | 203篇 |
2007年 | 180篇 |
2006年 | 169篇 |
2005年 | 169篇 |
2004年 | 159篇 |
2003年 | 148篇 |
2002年 | 130篇 |
2001年 | 137篇 |
2000年 | 109篇 |
1999年 | 80篇 |
1998年 | 60篇 |
1997年 | 48篇 |
1996年 | 47篇 |
1995年 | 38篇 |
1994年 | 21篇 |
1993年 | 17篇 |
1992年 | 13篇 |
1991年 | 19篇 |
1990年 | 13篇 |
1989年 | 8篇 |
1988年 | 9篇 |
1987年 | 13篇 |
1986年 | 8篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 7篇 |
1982年 | 6篇 |
1981年 | 3篇 |
1980年 | 1篇 |
1979年 | 3篇 |
1978年 | 1篇 |
1977年 | 4篇 |
1976年 | 2篇 |
1973年 | 2篇 |
排序方式: 共有5238条查询结果,搜索用时 15 毫秒
101.
102.
James L. Klosky Mary E. Randolph Fariba Navid Heather L. Gamble Sheri L. Spunt Monika L. Metzger 《Pediatric hematology and oncology》2013,30(4):252-260
To assess sperm cryopreservation among males newly diagnosed with cancer aged 13 years and older, attending oncologists assigned infertility risk (yes/no) to patients and reported whether their patients engaged in sperm cryopreservation. Only 28.1% of informed at-risk patients banked sperm. Utilization of sperm banking was significantly associated with a diagnosis of central nervous system (CNS) malignancy or non-CNS solid tumor diagnosis, higher socioeconomic status, and not being a member of an Evangelical religious group. These results suggest that sperm banking is underutilized among adolescent males newly diagnosed with cancer, and that strategies to increase the engagement in this fertility preservation method are needed. 相似文献
103.
N. Bach H. Tuomilehto C. Gauthier A. Papadakis C. Remise F. Lavigne G. J. Lavigne N. Huynh 《Journal of oral rehabilitation》2013,40(11):818-825
Maxillary transverse deficiencies (MTD) cause malocclusions. Rapid maxillary expansion treatment is commonly used treatment for correcting such deficiencies and has been found to be effective in improving respiration and sleep architecture in children with obstructive sleep apnoea (OSA). However, thus far, the effect of surgically assisted rapid maxillary expansion (SARME) treatment on sleep architecture and breathing of normal subjects has not been assessed. We hypothesised that sleep quality will improve after maxillary expansion treatment. The objective of this study is to access the effect of maxillary expansion treatment on sleep structure and respiratory functions in healthy young adults with severe MTD. This is a prospective and exploratory clinical study. Twenty‐eight consecutive young adult patients (15 males and 13 females, mean age 20·6 ± 5·8 years) presenting with severe MTD at the orthodontic examination were recruited into the study. All the participants underwent a standardised SARME procedure (mean expansion 6·5 ± 1·8 and 8·2 ± 1·8 mm, intercanine and intermolar distance, respectively) to correct malocclusion caused by MTD. An overnight in‐laboratory polysomnography, before and after the treatment, was performed. The mean follow‐up time was 9 months. The main outcome parameters were the changes in sleep architecture, including sleep stages, arousals, slow‐wave activity (SWA) and respiratory variables. Before surgery, young adult patients with MTD presented no evidence of sleep breathing problems. At baseline sleep recording, 7 of 28 (25%) had apnoea‐hypopnoea index (AHI) ≥ 5 events per hour. No negative effect of the SARME was observed in questionnaires or sleep laboratory parameters. In the patients with a higher baseline AHI (AHI ≥ 5 h of sleep), we observed a reduction in AHI after surgical treatment (P = 0·028). SARME did not have a negative effect on any sleep or respiration parameters in healthy young individuals with MTD. It normalised the breathing index in the patients with a mild AHI index. 相似文献
104.
Marcello Migliore Damiano Calvo Alessandra Criscione Francesco Borrata 《Journal of thoracic disease》2015,7(9):E378-E380
The uniportal-video assisted thoracic surgery (VATS) technique comprises operations which can be performed with skin incisions ranging from 2 to 8 cm and the manifest result of the introduction of the uniportal lobectomy had made possible to increase rapidly the number of published papers on this subject. Many of the large ensuing literature report incomplete historical information on uniportal VATS, and doubts exist about the indication of uniportal VATS for some thoracic oncologic pathologies. Known limitations have been overcome. On the other hand, the modern thoracic surgical team includes one surgeon, one assistant and a scrub nurse, and it is clear that the new generation of thoracic surgeons need to use the “less” used hand. The new technology which permitted the introduction of the uniportal VATS could influence the future need of thoracic surgeons worldwide. 相似文献
105.
目的 了解非梗阻性无精子症患者的生育生活质量现状及其影响因素。
方法 选取生殖中心就诊的311例非梗阻性无精子症患者,采用一般情况问卷、简明中文版生育生活质量量表及社会支持评定量表进行横断面问卷调查。
结果 非梗阻性无精子症患者生育生活质量得分为(65.55±13.52)分。回归分析显示,不育年限、家庭年收入、接受辅助生殖技术治疗次数和社会支持为非梗阻性无精子症患者生育生活质量的影响因素,可解释总变异的35.4%。
结论 非梗阻性无精子症患者生育生活质量较低,医护人员应重点关注不育年限长、家庭收入低、接受辅助生殖技术治疗次数多及社会支持水平低者,采取针对性干预措施提高其生活质量。 相似文献
106.
目的:报道一例辅助生殖技术(ART)助孕后的宫颈妊娠合并结核复发,讨论其相关病因、诊断及治疗方法。方法:通过病例报道和相关文献复习,对宫颈妊娠的病因、诊断、治疗、结核复发以及与ART的关系进行分析。结果:宫颈妊娠合并结核发生率极低,一旦发生不良结果,对患者影响巨大,早期诊断和及时治疗尤为重要。结论:ART过程中对可疑结核复发患者要及时诊断、及早处理。 相似文献
107.
《Foot and Ankle Surgery》2022,28(7):1069-1075
BackgroundAnkle fracture displacements cause significant discomfort to the patient and can compromise soft tissues including the neurovascular structures. Prompt reduction and plaster splint application are vital in the early management of these potentially limb-threatening conditions. The process can be distressing for the patient often requiring additional personnel or equipment. We have used a novel technique of Gravity Assisted Reduction of Ankle (GARA) fractures and compared the results with the Traditional Manipulation and Reduction (TMR) technique.Material and methodsWith adequate analgesia, the patient turns to lay either in lateral or prone position depending on fracture pattern, thus permitting gravity to gradually aid in reduction and hold the fracture in place while Plaster Of Paris (POP) is applied. We performed a retrospective comparative study of GARA vs TMR using validated radiological parameters to assess the quality of reduction with both techniques.Results21 patients had GARA technique, in comparison with 19 patients in TMR group. All measured radiological parameters showed similar improvement in both the groups, despite the fact that the pronation-external rotation injury pattern was more often seen in the GARA group. Intravenous sedation and monitoring were needed in 10 patients of TMR group, none in GARA group. On an average 4 personnel needed for TMR, but only 2 personnel needed for GARA technique.ConclusionGravity assisted ankle fracture reduction is a simple, effective and reproducible alternative technique to TMR, with no need of intravenous sedation along with fewer people needed to perform the procedure.Level of evidence3b 相似文献
108.
109.
《International journal of oral and maxillofacial surgery》2019,48(8):1028-1031
Suspicious radiological findings in the jaw bone require histopathological examination for the confirmation of a diagnosis. As pathologies in this region are difficult to reach or are in close proximity to relevant anatomical structures, e.g. tooth roots or nerves, they often represent a challenge. Such factors may adversely affect the predictability of the surgical outcome of a biopsy of the osseous tissues. This technical note introduces a novel method for performing a digitally planned, guided biopsy. For this purpose, a cone beam computed tomography scan and an intraoral scan are superimposed using specific planning software. The resulting three-dimensionally printed, tooth-supported drilling template is designed for a trephine biopsy. It allows a precise, minimally invasive approach, with an exact three-dimensional determination of the biopsy location prior to surgery. The risk of devitalization of the neighbouring teeth or possible damage to the nerve structures can be minimized. Furthermore, a small access flap can be sufficient. In summary, the method of bone biopsy presented here allows high precision and greater predictability for biopsy sampling and is minimally invasive for the patient. 相似文献
110.
《International journal of oral and maxillofacial surgery》2014,43(3):316-322
The aim of this retrospective study was to investigate the amount of skeletal and dental expansion in patients submitted to surgically assisted rapid palatal expansion (SARPE). The sample consisted of 21 patients (14 female and seven male) with a mean age of 25.4 years (range 17.4–41.8 years). Postero-anterior (PA) cephalograms were taken pre-expansion (T1), immediately after expansion (T2), and at post-expansion retention of 120 days (T3). SARPE promoted significant transverse skeletal changes, which were maintained from T2 to T3. Dentoalveolar expansion and dental tipping were also observed in the region of the first molars and first premolars; however the net effect at the first molars was significantly less than that at the first premolars. No statistically significant effect on the width of the nasal cavity was observed. The findings indicate that peculiarities inherent to dental effects may influence the clinical options for SARPE. Skeletal expansions with SARPE were significant and stable. Dental changes were different between molars and premolars. The transverse changes after SARPE should be observed for future procedures related to the retention and the completion of orthodontic treatment. 相似文献