《中国药房》1990～2008年高被引论文研究

目的:研究《中国药房》的高被引论文,为了解我国目前药物研究与应用领域的相关概况提供参考。方法:利用《中国期刊全文数据库》和《中国引文数据库》对《中国药房》1990～2008年的被引频次≥10次的高被引论文进行文献计量学分析。结果:被引频次≥30次的论文有32篇,其被引用时间主要集中在论文发表后2～6年;被引频次≥10次的论文有349篇,其发表时间主要集中在1996～2005年。高被引论文主要是涉及医院药学方面的论文,其次是药事管理和药剂学,再则综述文章的被引率也较高。结论:从《中国药房》所发表文章的内容来看,我国目前药物研究与应用领域的热点和焦点问题是安全合理用药、药学服务、药物经济学方法研究与应用等。     

我院药品价格层次与消费分析

目的：了解医院药品价格层次及各层次中药品的消费情况,为医院药事管理人员及药学人员,以及药品价格管理的行政部j．-j宏观调控药品价格提供参考。方法：对我院使用量居前的西药价格进行药品品种数、消费额及各自所占比例的分层次分析。结果：单价低于50元的药品品种数占医院常用药物的75．11％,消费金额比例为59．86％,即单价较低的药物不论从品种上还是销售金额上都占有绝对大的比例;零差率药品的品种数量虽然少于非零差率药品的品种数量,但是销售金额却高于非零差率药品,说明患者所用药物以零差率药物为主,非零差率药物为辅。医院获利最大药物层次位于20—80元。结论：通过多次政策性降价,医院药品价格层次、消费、比例更趋合理,零差率政策实行后,老百姓确实获得了实惠。     

零缺陷理念在我院药房调剂工作中的应用

目的:为实现药房调剂工作零差错、零投诉提供参考。方法:总结我院开业以来药房调剂工作经验教训,用零缺陷理念持续改进和完善调剂管理,在引导全员参与防范差错和纠纷、改善服务态度和提高沟通技巧、人员合理配置和用人扬长避短、提高药学人员专业素质和规范操作规程、建立调剂差错隐患登记交流制度、对临床医师进行合理用药培训等方面进行实践。结果:应用零缺陷理念管理后的两年多来,保持药房调剂工作零差错、零投诉。结论:引导全体药学人员用零缺陷理念指导调剂工作,制定一系列预防缺陷的管理制度和发现隐患持续改进的措施,倡导和努力实践以人为本的药师关怀管理模式,是保持调剂工作零差错、零投诉的基本措施。     

我国基层医疗卫生机构药品“零差率”政策实施现状及问题文献分析

目的:了解我国基层医疗卫生机构药品"零差率"政策的实施现状、效果及存在的问题。方法:采用文献研究法,设定文献纳入/排除标准,制定文献检索策略并进行文献检索,将检索到的文献进行初步筛选和质量评价,对符合要求的文献进行重点信息摘录、综合分析并得出结果。结果:药品"零差率"政策实施后,药品价格下降幅度较大,基层医疗卫生机构门诊人/次数上升,次均处方的药品数量和费用下降;同时,该政策还存在不规范方面,如地区间发展不平衡、"零差率"药物种类较少、药品价格仍然虚高、政府补偿不足、"零差率"药品断货等。结论:在评价药品"零差率"政策实施效果时,设计较为严谨的研究未被发现;药品"零差率"政策评价指标体系尚未建立;居民对"零差率"政策认知方面的研究较少;对药品"零差率"政策的实施监管及控制的研究较少;对于"零差率"目录以外的药品是否应该销售的研究基本上没有涉及;如何建立完善的药品供应体系需要进一步研究。     

30例零位牵引治疗肱骨近端骨折临床观察

目的：观察零位牵引治疗肱骨近端骨折临床效果。方法：30例肱骨近端骨折闭合复位后,进行零位牵引,以3周检查后决定是否拆除,胸前位再固定1周后,开始肩关节的功能锻炼,采用Neer标准评定肩关节功能。结果：30例患者通过零位牵引治疗后,优22例（73.3%）,满意6例（20%）,不满意2例（16.7%）,失败0例（0%）。结论：零位牵引方法的优点是解除牵引后肩关节能够快速恢复至正常功能位,病人痛苦少,无需手术,是较为简便,又确实可行的保守治疗方法之一。     

间歇性外斜视患者交叉视差和非交叉视差的临床观察

目的　了解间歇性外斜视患者交叉视差和非交叉视差的临床变化。方法　对 5 5例间歇性外斜视患者 ,术前应用颜少明的《立体视觉检查图》检测其近零视差、交叉视差及非交叉视差 ,并根据检测情况分为 3组进行分析。结果　第 1组 2 5例 ,近零视差立体视锐度正常者占 4 8 0 % ,其交叉视差和非交叉视差立体感知度检测值均不在正常范围 ,交叉视差者的立体感知度检测值比非交叉视差者大 ,差异有显著意义 (t =84 3 5 ,P <0 0 0 0 1)。第 2组 2 6例 ,近零视差立体视锐度正常者占30 8% ,其交叉视差立体感知度检测值不在正常范围 ,未见有非交叉视差者。第 3组 4例 ,为仅查到不正常的近零视差立体视锐度者。 5 5例中 ,无近零视差仅和非交叉视差共存者 ,也无交叉视差和非交叉视差各自独立存在者 ,亦无交叉视差和非交叉视差两者共存者。结论　 (1)本组间歇性外斜视患者近零视差立体视锐度及交叉视差和非交叉视差立体感知度不健全 ;(2 )间歇性外斜视患者视差的损害顺序依次为非交叉视差、交叉视差、近零视差。 (3)双眼黄斑颞侧视网膜对应的是交叉视差 ,双眼黄斑鼻侧视网膜对应的是非交叉视差     

零库存订货法在药品库存中的应用

目的:在保证临床用药的基础上,降低医院药品库存,加速库存药品资金周转。方法:利用库存周转率分析法对我院曾经使用的高低限量订货法和零库存订货法的库存成本、周转天数和周转率进行比较。结果:2种方法平均库存成本分别为175.36万元、158.11万元,无统计学差异(P=0.213),平均周转天数分别为13.03、9.64d,有统计学差异(P=0.017),平均周转率分别为236.99%、314.67%,有统计学差异(P=0.027)。结论:零库存订货法较好地保证了库存药品不积压、不断货,降低费用,节约成本,加快了药品的周转率。     

学术期刊中的零被引论文特征分析——以编辑出版类核心期刊为例

【目的】为国内编辑出版类作者的选题及同行编辑组稿、选稿提供一定的参考依据,以期能对编辑出版类核心期刊学术影响力的提高有所裨益。【方法】以7种编辑出版类核心期刊2009年刊发的文章在6年内（2009–2014年）的零被引论文为研究对象,从论文的不活跃性入手,参考相关高被引论文的研究思路,对这些论文的相关文本信息、相关作者信息、主题内容、基金资助情况、论文特征等进行统计分析。【结果】零被引论文的出现与期刊的H指数、影响因子及其论文的语种、类型、学科分布等有着很大的相关性。【结论】期刊应该减少或避免零被引论文的出现,在注重基础理论的同时,要能够发现那些具有较大创新的优质稿件,提高期刊的学术影响力。     

A review of suspected cases of driving under the influence of drugs (DUID) involved in traffic accidents in Istanbul (Turkey)

Nowadays traffic accidents, which have high mortality and morbidity, are an important public health problem. The association between the use of alcohol and/or drugs by drivers and the increased risk of traffic accidents with a high risk of death and injury has been well described in the literature.This study aimed to review the incidence of cases of driving under the influence of drugs (DUID) among all cases of driving under the influence (DUI) of alcohol and/or other drugs involved in traffic accidents and to evaluate the type of the psychoactive drugs (with or without alcohol) detected in blood samples in Istanbul and its surrounding area. This study is the first investigation on the subject of DUID cases in Turkey.The reports of the Istanbul Toxicology Department of the Council of Forensic Medicine (Turkey) on suspected DUID cases involved in traffic accidents between 1 July 2010 and 30 June 2011 were retrospectively reviewed for alcohol and/or drug use.Alcohol analysis was requested in 4274 suspected DUI cases, whereas drug along with alcohol analysis was requested in only 91. The rate of suspected DUID cases (n = 91) among the suspected DUI cases (n = 4274) was only 2.1% and in this study, we evaluated only the DUID cases in detail. Alcohol was present in 44% of suspected DUID cases. Psychoactive drugs were present in 15.4% of cases. The incidence among 46 confirmed DUID cases was found to be 17.4% for cannabis, 8.7% for benzodiazepines, 4.3% for barbiturates, 4.3% for antidepressants, 2.2% for cocaine and 2.2% for amphetamines.Although there is a zero-tolerance approach for DUID in the Turkish regulations, it is not well recognised and not inspected by police and legal authorities who are responsible for taking measures in traffic accidents and for routine traffic controls in Turkey. It is concluded that psychoactive drugs should be checked as well as alcohol in all traffic accident cases and roadside controls.     

Efficacy and Safety Results of a Drug-Free Cosmetic Fluid for Perioral Dermatitis: The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) Study

Background

Perioral dermatitis (POD) is a common inflammatory skin disease without standard therapy.

Objective

We sought to evaluate the clinical value of a soothing fluid for the treatment of POD.

Methods

We included 51 patients with POD in this 8-week clinical trial. The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) study had an open-label design and involved twice-daily application of Toleriane Fluide, a soothing cosmetic fluid. Clinical assessment of POD was performed with a predefined questionnaire including the POD severity index (PODSI). Control visits were made after 4 and 8 weeks of treatment.

Results

The results were compared with those of a historical control group treated with a vehicle cream. Patients treated with the soothing fluid showed a continuous and significant improvement of the PODSI over time. The improvement of PODSI observed with the soothing fluid was better, but not significantly better, than that observed in the historical controls. In addition, the subjective complaints of patients such as disease burden, itching, distension of the skin, and appearance improved during treatment.

Conclusion

A soothing fluid could be a clinically useful treatment option for POD.