长三角一体化背景下安徽省口腔专科医疗联合体建设现状调查

目的 调查安徽省口腔专科医联体建设现状,分析安徽省口腔专科建设存在的问题,为加快安徽省口腔专科建设融入长三角地区医疗发展提供依据.方法 自行设计调查问卷,于2020年11～12月对安徽省口腔专科医联体内所有医院进行调查.发放问卷36份,回收有效问卷32份.运用统计描述、χ2检验和t检验对资料进行统计分析.结果 被调查的医院共有医护人员487人,其中男性286人(58.73％),女性201人(41.27％),医护比为1:0.43;技工24名,医技比为1:40;牙椅499张,牙椅与技工之比20.79:1;床位494张,床护比1:0.30;仅3个诊疗项目在调查医院中全部开展;加入与未加入其他医联体两类医院医护人员一般情况比较发现,职称、学历与年龄的差异有统计学意义(P<0.05);口腔人才匮乏,研究生及以上学历仅占30.80％.结论 安徽省口腔专科建设能力不足,通过对人才队伍及信息化建设等方式,逐步缩小与沪、苏、浙地区间差异,推进安徽省口腔专科加速融入长三角地区医疗发展.     

塔里木盆地东南部啮齿动物调查

１９９８年５月和７月,作在塔里木盆地东南部下夹９５０夹次,捕获啮齿动物５４只,隶属４科７属７种,捕获率为５．６８％,其中包括大沙土鼠２７只,证实在塔里木盆地东南部地区确有大沙土鼠分布。     

三峡建坝后长江江苏段水位变化对血吸虫病流行影响的研究 Ⅲ.不同水深对血吸虫虫卵孵化、毛蚴感染钉螺的影响

为研究三峡建坝后长江江苏段水位春季提早升高对血吸虫及血吸虫病传播的影响,对不同深度水下血吸虫虫卵的孵化率及水下钉螺对毛蚴的易感性进行了观察。结果显示,水淹深度与水下血吸虫虫卵孵化率及水下钉螺对毛蚴的易感性均呈非常显著负相关。研究提示,三峡建坝后４ 月份提早浅水水淹有利于受淹滩上虫卵的孵化及毛蚴感染钉螺。     

海南岛两株甲病毒基因组3′末端核苷酸序列的克隆与分析

目的　从分子水平鉴定海南省分离的两株甲病毒 (HBb17和M1病毒 )。方法　采用RT-PCR方法 ,分别扩增两株病毒基因组的 3′末端核苷酸序列 ,扩增产物经亚克隆 ,筛选重组子并测定核苷酸序列对序列进行分析。结果　HBb17和M1病毒分别扩增出约 1 6kb和 1 3kb的特异片段。序列分析表明 ,在 3′末端非翻译区HBb17病毒与罗斯河病毒 (国际标准株T48病毒 )核苷酸同源性为99 % ,M1病毒与鹭山病毒 (SAG)同源性为 98% ;两病毒结构基因的E1区序列 ,HBb17病毒与罗斯河病毒核苷酸 (氨基酸 )同源性为 99% (99% ) ,M1病毒与鹭山病毒核苷酸 (氨基酸 )同源性为 97% (99% ) ,M1病毒与盖塔病毒同源性为 94% (98% )。结论　序列分析表明 ,海南岛分离的HBb17病毒属于罗斯河病毒 ,M1病毒可能是鹭山病毒或盖塔病毒的变异株     

Isolation and characterization of microcystins from a river nile strain of Oscillatoria tenuis Agardh ex Gomont.

The River Nile is the major source of drinking water in Egypt, however, increased eutrophication due to agricultural, municipal and industrial runoff has contributed to the growth of toxin producing cyanobacteria. This study describes the isolation and characterization of microcystins (MCYSTs), cyclic heptapeptide hepatotoxins, from a rare strain of Oscillatoria tenuis, isolated from the River Nile at Sohag province in July 1995. The MCYST concentration of laboratory-cultured O. tenuis strain E6 was found to be 0.3 mg/g freeze-dried weight determined by enzyme-linked immunosorbent assay (ELISA). Two microcystins, 1 and 2, were isolated from lyophilized cells using solid phase extraction and reversed-phase high performance liquid chromatography (HPLC). Structures were assigned based upon their amino acid analyses, electrospray ionization mass spectrometry (ESIMS, ESIMS-CID-MS), high resolution fast atom bombardment mass spectrometry, and nuclear magnetic resonance data (¹H and ¹H COSY NMR). Toxin 1 was identified as MCYST-LR, and toxin 2, a new MCYST, as MCYST-LHArg ([ -homoarginine⁴]). Previous studies indicate that Oscillatoria agardhii strains produce demethylated MCYSTs (containing -Asp and/or dehydroalanine). This is the first report of a toxic O. tenuis, strain E6, one which produces a fully methylated MCYST, MCYST-LR and a new -homoarginine containing MCYST, MCYST-LHArg.     

Chronic toxicity and hazard assessment of an inorganic mixture simulating irrigation drainwater to razorback sucker and bonytail

We conducted two 90 day chronic toxicity studies with two endangered fish, razorback sucker and bonytail. Swim‐up larvae were exposed in a reconstituted water simulating the middle Green River. The toxicant mixture simulated the environmental ratio and concentrations of inorganics reported in a Department of the Interior study for the mouth of Ashley Creek on the Green River, and was composed of nine elements. The mixture was tested at 1X, 2X, 4X, 8X, and 16X where X was the measured environmental concentration (2 μg/L arsenic, 630 μg/L boron, 10 μg/L copper, 5 μg/L molybdenum, 51 μg/L selenate, 8 μg/L selenite, 33 μg/L uranium, 2 μg/L vanadium, and 20 μg/L zinc). Razorback sucker had reduced survival after 60 days exposure to the inorganic mixture at 8X, whereas growth was reduced after 30 and 60 days at 2X and after 90 days at 4X. Bonytail had reduced survival after 30 days exposure at 16X, whereas growth was reduced after 30, 60, and 90 days at 8X. Swimming performance of razorback sucker and bonytail were reduced after 60 and 90 days of exposure at 8X. Whole‐body residues of copper, selenium, and zinc increased in a concentration‐response manner and seemed to be regulated at 90 days of exposure at 4X and lower treatments for razorback sucker, and at 8X and lower for bonytail. Adverse effects occurred in fish with whole‐body residues of copper, selenium, and zinc similar to those causing similar effects in other fish species. Comparison of adverse effect concentrations with measured environmental concentrations showed a high hazard to the two endangered fish. Irrigation activities may be a contributing factor to the decline of these endangered fishes in the middle Green River. ©2000 John Wiley & Sons, Inc. Environ Toxicol 15: 48–64, 2000     

长三角地区经济与能源的协调发展

长三角地区是我国经济发展的龙头,正逐渐成为世界制造业基地。但是,目前该地区在经济快速发展的同时,能源短缺的矛盾日益凸现,粗放式、高耗能的经济增长方式已经严重制约着地区经济的可持续发展。今后长三角地区一方面要大力发展能源产业,充分开发利用风力发电和太阳能等可再生能源,提高能源自给能力;另一方面必须加快地区经济一体化进程,促进区域经济的协调发展,优化经济结构,大力发展服务业,积极培育新型支柱产业,加速产业结构转型升级,从而构建资源节约型的经济增长模式。     

危重新生儿长三角一体化转运的实践与思考

目的总结分析长三角地区危重新生儿转运工作。方法回顾分析2016年至2019年上海交通大学医学院附属新华医院在长三角地区危重新生儿的转运及转归情况。结果共转运3508例新生儿,其中转运危重新生儿居前3位的分别为先天性心脏病、新生儿肺炎和新生儿黄疸;转运新生儿中痊愈2.48%,好转90.13%,自动出院6.7%,死亡0.68%。结论长三角地区危重新生儿转运亟需建立一体化协作网络。     

三峡水库蓄水前后长江部分江段水质变化

目的 了解三峡工程135m水位蓄水后长江部分江段水质的变化情况。方法 以长江丰都至巫山段的6个城市的8个水质断面作为监测点,按照水质采样方案设计技术规定(GB12997-1991)进行布点,在平水期和丰水期共采集水样96份,分别按照相应的国家标准方法进行pH、溶解氧、生化需氧量、化学耗氧量、挥发酚、总氰化物、砷、汞、六价铬、石油类、铅、镉、氨氮、高锰酸盐指数、总磷、总氮等16项水质指标的检测,将监测结果与往年同期总体水质和背景浓度进行比较。结果 三峡水库135m蓄水前后总体水质仍属Ⅱ、Ⅲ类,无明显变化。影响库区总体水质的主要污染因子是总磷、总氮。结论 三峡水库135m蓄水未对库区长江水质造成显著的负面影响。