The Drug Manufacturer as a Drug Information Resource

Pharmacists use a myriad of drug resources for patient care; however, the drug manufacturer is often overlooked and underutilized as a resource for drug information. Pharmaceutical companies have a medical information department that is responsible for providing drug information to pharmacists and the public about the company’s products. This article will explain the purpose and functions of the medical information department within a pharmaceutical company. In addition, the type of information that may be requested and the ways to request drug information will be discussed.     

Results of shared learning of a new magnetic seed localisation device – A UK iBRA-NET breast cancer localisation study

IntroductionShared learning is imperative in the assessment and safe implementation of new healthcare interventions. Magnetic seeds (Magseed®) potentially offer logistical benefit over wire localisation for non-palpable breast lesions but few data exist on outcomes comparing these techniques. A national registration study (iBRA-NET) was conducted to collate device outcomes. In order to share learning, thematic analysis was conducted to ascertain early clinical experiences of Magseed® and wire guided localisation and explore how learning events may be applied to improve clinical outcomes.MethodsA qualitative study of 27 oncoplastic surgeons, radiologists and physicians was conducted in January 2020 to ascertain the feasibility and challenges associated with Magseed® versus wire breast localisation surgery. Four focus groups were asked to discuss experiences, concerns and shared learning outcomes which were tabulated and analysed thematically.ResultsThree key themes were identified comparing Magseed® and wire localisation of breast lesions relating to preoperative, intraoperative and postoperative learning outcomes. Percutaneous Magseed® detection, instrument interference and potential seed or wire dislodgement were the most common issues identified. Clinician experience suggested Magseed® index lesion identification was non-inferior to wire placement and improved the patient pathway in terms of scheduling and multi-site insertion.ConclusionsProspective shared learning suggested Magseed® offered additional non-clinical benefits over wire localisation, improving the efficiency of the patient pathway. Recommendations for improving breast localisation technique, appropriate patient selection and clinical practice through shared learning are discussed that may aid other surgeons in the adoption of this relatively new technique.     

Grafting and electrical stimulation of the auditory nerve in cats

Summary The effect of implanting wire electrodes into the cochlea is limited by the deficit of nerve fibers in most diseases of the cochlea. Therefore, in a series of experiments it was tried, for the first time, to direct new outspreading nerve fibres into the afferent acoustic nerve by grafting a motor nerve to it. A second series of experiments should demonstrate the possibility of direct electrical stimulation of the eigths nerve by implanting wire electrodes via the transoccipital approach. The electrically evoked potentials, recorded at the auditory cortex, were compaired to potentials evoked by auditory stimulation. The answers to acoustic or electric stimulation showed no significant difference.Unterstützt von der Deutschen Forschungsgemeinschaft     

An Unusual Complication of a Colonic Wallstent

We report a case of delayed perforation of normal colonic wall by the wire tips of an enteral Wallstent, which had successfully been used to treat a malignant obstruction of the sigmoid colon. Perforation occurred 5 days following insertion and despite surgery, resulted in fatality. Though perforation at the tumor site is a recognized complication during or following colonic stent placement, it is rare for the ends of the stent to perforate through nondiseased bowel wall. The site of the obstructing lesion and thus the position of the stent on a bend in the colon may be a contributory factor.Correspondence to: P.N. Panto; email: Philip.Panto@sfh-tr.nhs.uk     

线穗植入法治疗泪点阻塞

目的 探讨线穗植入法治疗泪点阻塞的效果。方法 对43例(53眼)进行线穗植入治疗泪点阻塞。用1-0或3-0手术缝线重复对折并捻成绳样，长约20mm，粗的直径0．8～1．0mm。在其两端用3．0缝线对折作固定引线，以自制的探针针头将线穗植入泪点共30天。7～10天复诊清洗1次。结果 43例(53眼)中，治愈36例(45)眼，治愈率达84．91％。结论 线穗植入治疗泪点阻塞是一种简便、安全、有效的方法，治愈率高。     

坦索罗辛在输尿管中下段结石ESWL后的临床应用

目的：研究坦索罗辛在输尿管中下段结石ESWL（体外冲击波碎石）治疗后的排石作用.方法：510例输尿管中下段结石随机分成两组,组I为作为对照组,ESWL后口服氟哌酸、结石通、双氢克尿噻 组II为实验组,ESWL后在对照组的基础上加服坦索罗辛0.2mg/次,1次/日.观察时间为20天.结果：I组结石20天内排净率为62.3%（177/284）,II组排石净率为84.5%（191 / 226）.治疗组的排净率明显高于对照组.在治疗后两组肾绞痛的发生率亦有明显差异,因而对镇痛药的使用也明显不同.结论：坦索罗辛在输尿管中下段结石ESWL后能提高排石率、减少肾绞痛的再次发生率,且安全有效、可作为中下段输尿管结石ESWL的辅助排石方法.     

盐酸氨溴索注射液治疗小儿支气管肺炎的临床效果分析

目的探讨盐酸氨溴索注射液治疗小儿支气管肺炎的临床效果。方法选取2012年10月~2013年2月在我院收诊治疗的小儿支气管肺炎病例78例,随机分为观察组39例与对照组39例。观察统计并记录两组小儿患者在治疗后的不同临床表现及治疗效果。结果观察组治愈率(97.4%)明显优于对照组(74.4%),两组比较差异有统计学意义(<0.05),不良反应发生率低。结论盐酸氨溴索注射液用于临床治疗小儿支气管肺炎治疗效果好,治疗时间快,能提高小儿支气管肺炎的治愈率,且不良反应较少,效果显著,值得临床推广应用。     

胃底静脉曲张用钛夹与尼龙绳辅助的效果分析

目的 探讨胃底静脉曲张(IGV1型及GOV2型)内镜下钛夹夹闭辅助与尼龙绳圈套辅助治疗的临床价值.方法 回顾性分析2018年6月—2019年12月我院肝硬化合并胃静脉曲张(IGV1型及GOV2型)出血患者36例,其中行钛夹封闭后硬化剂联合组织胶治疗者有20例,另有16例给予胃底静脉曲张尼龙绳圈套后再行硬化剂联合组织胶治...     

带线锚钉联合骨隧道缝合治疗髌骨下极骨折的临床疗效

目的 探讨对髌骨下极骨折患者行带线锚钉联合骨隧道缝合治疗的临床效果.方法 45例髌骨下极骨折患者,按照随机分组法分为对照组(22例)和试验组(23例).对照组采用常规钢丝张力带固定治疗,试验组采用带线锚钉联合骨隧道缝合治疗.比较两组患者手术时间、骨折愈合时间、术后6个月B?stman髌骨骨折功能评分、膝关节活动度、术后...