奥曲肽及垂体后叶素治疗食管胃底静脉曲张破裂出血的效果观察

①目的 比较奥曲肽和垂体后叶素治疗肝硬化食管胃底静脉曲张破裂出血的临床效果。②方法 将９２例（１０５次）食管胃底静脉曲张破裂出血病人随机分为奥曲肽组（５０例５８次）和垂体后叶素组（４２例４７次）,分别给予奥曲肽和垂体后叶素治疗,每隔０．５ｈ冲洗胃腔吸取胃液１次,比较两组止血率。③结果 奥曲肽组和垂体后叶素组８ｈ内止血率分别为６０．３％,１７．０％,差异有极显著性（Ｘ＾２＝２０．１５,Ｐ〈０．０１）     

有否静脉溶栓的急性心肌梗死63例尸解病理分析

探讨溶栓治疗的并发症。方法急性心肌梗死住院死亡并行尸体解剖６３例,２６例曾给予溶栓治疗,３７例行常规治疗。结果两组性别、年龄、ＣＨＤ的危险因素,梗死次数,心肌酶学、梗死部位及血管狭窄程度均无明显差异。结论ＡＭＩ早期溶栓治疗心脏破 发生率较非溶栓组明显升高。     

宫内节育器与兔子宫内膜生成内皮素的研究

自制金属单环放入兔左侧子宫角腔内,有明显抗生育效果,此为动物模型。选10只成年雌兔分为二组,将节育环放入每只兔左侧子宫角腔内,右侧为对照。一个月,三个月取子宫内膜,进行形态学观察,内皮素免疫组化定位及内膜组织中内皮素含量的测定。结果显示:内膜形态无明显改变,只在少数局部淋巴细胞略多。内皮素免疫组化定位显示左侧子宫角阳性反应比右侧强,一个月和三个月结果相似。放射免疫测定的内膜组织中内皮素含量左侧明显高于右侧。揭示金属单环引起内膜组织生成内皮素增加。     

RK术后严重眼球破裂伤的手术治疗：附3例报告

报告３例ＲＫ术后严重眼球破裂伤的手术效果。方法部分穿透性角膜移植及联合瞳孔孔成形,前段玻璃体切除,角膜裂伤修补及后段玻璃体切除视网膜复位术。结果３例均保存了眼球。结论ＲＫ术后眼球破裂伤虽然严重而复杂,但通过穿透性角膜移植术及联合手术治疗,仍有可能保存眼球和恢复部分视力。     

Decrease of some metabolic and physiologic effects of diazoxide by propranolol in rat

Summary Diazoxide significantly decreased the blood pressure and relaxed the uterine muscle in anaesthetized normotensive rats. A marked elevation of blood glucose followed the intravenous injection of diazoxide. The hyperglycemic and the uterine relaxing response could be significantly decreased by injection of propranolol prior to diazoxide. The hypotensive effect was not diminished by propranolol, however. In liver and uterus the content of cAMP was increased following diazoxide treatment in vivo. The rise in cAMP could be completely inhibited by propranolol, indicating a -receptor stimulation being the cause of the cAMP elevation.     

Electron microscopy and X-ray microanalyses of uterine epithelium from lead-injected mice in an experimental delay of implantation

Mice in experimental delay of implantation were injected intravenously with 75 g · g^–1 body weight of lead chloride, corresponding to a dose of lead of about 56 g · g^–1 body weight. Delay of implantation was obtained by ovariectomy 3 days after mating followed by a depot dose of progesterone every fifth day. Electron microscopy showed that the uterine lumen, which was closed in control mice, was opened in lead-injected mice. This morphology suggested that lead caused an increase in uterine secretion. X-ray microanalysis of pyroantimonate precipitates in the uterine epithelium of injected mice demonstrated lead in the precipitates, suggesting that lead could have a direct effect on the function of the uterine epithelium and that lead also could be secreted into the uterine lumen and affect the blastocysts.     

Cystoid macular edema in anterior chamber lens implantation following posterior capsule rupture

By comparing the incidence of cystoid macular edema (CME) in three groups of patients having different surgical procedures, we attempted to assess the role of vitreous loss as a risk factor for CME development. In the first group (n = 470), the surgical procedure was extracapsular cataract extraction followed by implantation of posterior chamber lens (EC-CE + PC-IOL). The second group (n = 42) had extracapsular cataract extraction which was complicated by posterior capsule rupture, and therefore anterior vitrectomy followed by implantation of anterior chamber lens had to be performed (ECCE + anterior vitrectomy + AC-IOL). In the third group (n = 22) the surgery was intracapsular cataract extraction followed by anterior chamber lens implantation (ICCE + AC-IOL). The third group was included in this follow up study to assess the role of AC-IOL as a possible causative factor for development of CME in uncomplicated cases of ICCE and AC-IOL. The difference of incidences of CME in the second and third group would therefore depend mostly on the vitreous loss. The incidence of CME diagnosed by fluorescein angiography in the first, second and third group was 1.5% (7/470), 35.7% (15/42) and 9.0% (2/22), respectively. All patients who developed CME were treated with combination of corticosteroid-antibiotic drops, dexamethasone retrobulbarly (40 mg/day) and peroral indomethacine (25 mg/day/6 weeks). This therapeutic regime resulted in only moderate improvement of visual acuity.Abbreviations AC-IOL anterior chamber intraocular lens - CME cystoid macular edema - ECCE extracapsular cataract extraction - ICCE intracapsular cataract extraction - IOL intraocular lens - PC-IOL posterior chamber intraocular lens     

应用B超与子宫内膜病理检查联合诊断异常子宫出血232例分析

目的探索子宫异常出血症的B超声象与子宫内膜病理检查的关系.方法对232例子宫异常出血患者采用B超检查后做子宫内膜活组织病理检查,对B超显示子宫内膜增厚≥5mm或者有异常回声者作观察组,B超正常者为对照组.结果观察组190例中病理检查显示正常子宫内膜21例(11.05%),异常子宫内膜169例(88.95%),其中不全流产33例、子宫内膜炎12例、子宫内膜增生过长及分泌不良98例、子宫内膜息肉及粘膜下肌瘤15例、子宫内膜恶性病变11例;对照组42例中有4例(9.53%)为不全流产外,其余无病理征.结论先采用B超探查子宫内膜,对有异常声象作诊括术进行病理检查是诊断子宫异常出血症较为方便、简捷、有效的方法.     

经动脉插管栓塞治疗自发性肝癌破裂

目的:探讨经动脉插管栓塞治疗自发性肝癌破裂出血的疗效。方法:比较自发性肝癌破裂出血的病人采用单纯支持治疗(SCA组)和经动脉插管栓塞治疗(TAE组)的临床效果。结果:TAE组较SCA组生存期明显延长,分别为(129.8±83.9)d,(3.8±5.9)d(P<0.01)。结论:对自发性肝癌破裂出血的病人应积极采用经动脉插管栓塞治疗,为患者赢得局部化疗的时机,明显延长患者的生存期。     

子宫腺瘤样瘤临床病理分析

目的 探讨子宫腺瘤样瘤的组织发生、临床病理特征及鉴别诊断。方法 对ll例子宫腺瘤样瘤的资料，进行综合分析，光镜观察。其中6例进行免疫组化标记。结果 年龄2l—58岁，临床表现无特征性，肿瘤好发子宫角、宫底处。光镜下表现为上皮样细胞形成腺样、腔隙、条索样结构，有些上皮样细胞可呈空泡状、印戒样。大多伴有平滑肌瘤或平滑肌增生。免疫组化：CK、EMA、VIM、Calretinin均阳性表达，而FⅦ因子相关抗原、CEA均阴性。结论 子宫腺瘤样瘤是一种良性病变，符合间皮来源，尤其注意的是：此瘤出现以空泡、印戒样细胞为主时，易误诊为腺癌或印戒细胞癌，结合免疫标记，可鉴别之。