Therapeutic apheresis in Asia: An Indonesia single center experience

In developing countries, like Indonesia, apheresis is still a relative new procedure. Nowadays, therapeutic apheresis procedures are performed in the field of hematology and neurology, especially in the teaching hospitals in Indonesia. Therapeutic apheresis procedure, that is, leukocytapheresis, therapeutic plasma exchange (TPE), and thrombocytapheresis are already performed. In the period 2009–2013, 204 apheresis procedures in 137 patients to reduce the leukocytes, 72 TPE procedures in 17 patients, and 14 thrombocyte reductions were performed in the Sardjito hospital, Yogyakarta, Indonesia. In the future, to improve the therapeutic apheresis implementation, it is important to increase the insurance coverage and also should be considered to introduce the apheresis medicine into the curriculum of appropriate physician programs in Indonesia. Especially in Indonesia, a lot of efforts are still being needed to improve implementation of therapeutic apheresis. J. Clin. Apheresis 30:139–140, 2015. © 2014 Wiley Periodicals, Inc.     

临床输液监控系统的设计

本文针对临床输液过程中出现的漏、停、输液速度改变等各种问题，讨论了一由单台微机和多个单片机通讯实现的多床输液自动监控、自动反应、自动报答系统的可行性，并给出了主要部分的硬件、软件设计方法。     

三甲达标中“护理管理软件系统”的建立及应用

本文系统地分析和总结了该院在上等达标中，“护理管理软件系统”的应用概况。通过对照标准逐项设计，收集、整理资料，目前已形成了科学的护理软件系统管理模式，并纳入惯性运行，为护理部管理及决策提供了科学的第一手资料。     

Software compensation improves the analysis of heterogeneous tumor samples stained for multiparameter DNA flow cytometry

Background: High concentrations of propidium iodide (PI), in combination with fluorescein isothiocyanate (FITC) and R-phycoerythrin (RPE) used for multiparameter DNA flow cytometry (FCM), cause spectral cross-talk into the green fluorescence channel (FL1). We have evaluated the use of post-acquisition software compensation (N-Color Compensation) in order to correct this spectral cross-talk caused by PI. Method: Cell mixtures were prepared consisting of keratin 8/18 FITC labeled, keratin 8/18 RPE labeled, and unlabeled MCF-7 breast carcinoma cells. DNA was stained with PI (100 μM). Post-acquisition software compensation was applied to correct the spectral cross-talk of PI fluorescence. Secondly, the distribution of the Ki-67 (FITC) protein during the cell cycle (PI) of SiHa cervical carcinoma cells (no software compensation) was compared to the Ki-67 expression pattern of SiHa cells, simultaneously stained for keratin 8 (RPE), after applying software compensation. Finally, software compensation was used to compare the relative levels of PCNA and p53 expression in two clinical ovarian cancer ascites specimens, stained for PCNA or p53 (FITC), keratin 8/18 (RPE), and DNA (PI), with a known p53 status (positive and negative, respectively). Results: The Ki-67 cell cycle-dependent pattern of a triply stained sample (Ki-67 (FITC), keratin 8 (RPE), and DNA (PI)) is restored after software compensation and the results are comparable to the Ki-67 distribution of a sample stained solely for Ki-67 and DNA. P53 expression could only be resolved after using software compensation in the p53 positive ovarian ascites (OA) sample. Conclusions: We conclude that software compensation is a robust and reliable post-acquisition method for the correction of RPE/PI spectral cross-talk, permitting better identification of weakly expressed proteins in heterogeneous clinical tumor samples stained for multiple cellular antigens and DNA using PI.     

论河北省卫生系统办公自动化管理系统

系统采用基于TCP/IP协议的国际互联网为基础,采用B/S结构,客户端采用IE浏览器,服务器端采用WINDOW2000的IIS作为服务器。其主要功能:工作督办、工作信息、电子邮件、收文、发文、图书管理、档案管理、车辆管理、日程管理、待办事宜、电子论坛、考勤管理等。     

Data Bank and Consulting System for Medical Management of Patiens with Acute Radiation Sickness

ＤａｔａＢａｎｋａｎｄＣｏｎｓｕｌｔｉｎｇＳｙｓｔｅｍｆｏｒＭｅｄｉｃａｌＭａｎａｇｅｍｅｎｔｏｆＰａｔｉｅｎｓｗｉｔｈＡｃｕｔｅＲａｄｉａｔｉｏｎＳｉｃｋｎｅｓｓ￥ＴａｎｇＺｈｏｎｇｍｉｎｇ；ＹｅＧｅｎｙａｏ；ＭａｏＢｉｎｇｚｈｉ；ＬｕｏＱｉｎｇｌ...     

Eigenstructure assignment with control gains optimization

Eigenstructure assignment using output feedback is reformulated using an auxiliary principle of minimization of control effort. In the general eigenstructure assignment procedure, the feedback gain matrix is uniquely determined for a set of explicitly specified desired eigenvalues and eigenvectors. However, for the controller design proposed in this paper, only the most necessary constraints are imposed on the desired eigenvalues and eigenvectors, and the unspecified model parameters of the closed-loop system are determined by minimizing the control effort. Numerical examples are presented for comparison of the proposed method with standard eigenstructure assignment methods, and an experimental example gives an insight into the feasibility of the proposed control algorithm with application to the vibration control of flexible structures undergoing forced vibration.     

医院制剂室的软件管理

为了探讨医院制剂室的软件管理 ,我们根据《医疗机构制剂配制质量管理规范》的要求 ,分析了我们的软件动态与静态资料 ,提出了自己的一些解决方案。     

自动麻醉记录系统

该研究将通过M icrosoft V isua l C 6.0和V isua l B as ic 6.0为主要的开发工具,SQL Server为数据库,采用客户端/服务器结构,设计出基于W indow s操作系统,网络环境下运行的应用程序,并将它们用于自动麻醉记录。该自动记录系统负责处理麻醉全过程中的相关病人信息,对医护现场的多种医疗设备:如监护仪、静脉输液泵、麻醉机等进行数据的实时自动采集、加工以及集成等,并在综合病人相关信息及生理参数的基础上自动输出麻醉记录单。该记录系统不仅提高了临床医师的工作效率,减低了麻醉医师的劳动强度,而且使麻醉记录更加准确和完整。     

Recurrent wavefront morphologies: A method for quantifying the complexity of epicardial activation patterns

We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21×24 array of unipolar electrodes (1 mm spacing), and the wavefronts are isolated. A correlation technique is used to compute the similarity between all possible pairs of the isolated wavefronts. From these data, the wavefronts are sorted into clusters, each of which represents a recurring wavefront morphology. We define multiplicity (M) as the number of clusters needed to account for 90% of the total activations in the VF episode.M measures the complexity of the rhythm. In repetitive patterns (e.g., sinus rhythm),M=1, indicating that the same morphology repeatedly activates the mapped region. Typically, in VF,M>1, with larger numbers representing more complex, disorganized patterns. As an example, we computedM at 5, 10, 15, and 20 sec after electrical induction of VF in six pigs.M decreased significantly (p<0.001), suggesting increasing organization during this period.