射频治疗血管运动性鼻炎（附55例总结）

目的：总结射频治疗血管运动性鼻炎的疗效。方法：血管运动性鼻炎患者采用射频治疗５５例,药物治疗53例,下鼻甲部分切除23例,并进行疗效比较。结果：射频治疗效果显著,55例近期疗效达到全部临床治愈,明显优于其它两种疗法（P＜0．01）。结论：确定射频治疗范围是保证疗效的先决条件,局部粘膜射频治疗程度是决定疗效的重要因素。射频疗法具有操作简便、快捷,反应轻、副作用少等优点;治疗常年变应性鼻炎同样有效。     

Radio-frequency thermal ablation with hypertonic saline solution injection of the lung: ex vivo and in vivo feasibility studies

The aim of this study was to assess the effects of simultaneous instillation of NaCl solutions during radio-frequency ablation (RFA) on the dimension of the ablated lesion in ex vivo bovine lung tissue and in vivo rabbit lung tissue. The RFA was induced in ex vivo bovine lung tissue which was inflated with room air and in vivo rabbit lung tissue by a 500-kHz RF generator and a 17-G cooled-tip electrode. In in vivo experiments, RFA was performed using CT guidance. The RF energy was applied for 5 min with or without instillation of 0.9 or 36% NaCl solutions. The changes in tissue impedance, current, power output, and temperature of the electrode tip were automatically measured. The maximum diameter of all thermal lesions was measured perpendicular to the electrode axis by two observers. In an ex vivo study, the mean lesion diameters using 36 and 0.9% NaCl solutions were larger than those of the control group: 51±8, 34±6, and 5±2 mm (p<0. 05). In in vivo rabbit lung tissue, the mean lesion diameter with NaCl solution (15.3±3.1 mm) was larger than that of the lesion without NaCl solution (8.5±1.4 mm; p<0.05). With instillation of NaCl solutions, a marked decrease of tissue impedance (>100 Ω) and corresponding increase of current flow occurred in both ex vivo and in vivo studies. This experimental study demonstrates that RF ablation with simultaneous NaCl solution infusion of the lung is more effective in achieving coagulation necrosis than conventional RFA procedure.     

Radio-frequency tissue ablation of the liver: in vivo and ex vivo experiments with four different systems

The aim of this study was to test the efficacy of four different radio-frequency ablation (RFA) systems in normal hepatic parenchyma in large animals. The RFA was applied to pig livers in vivo and to calf livers ex vivo using the Radionics cluster needle, RITA starburst XL needle, Radiotherapeutics Le Veen 4.0 needle, and the Berchtold 14-G saline-perfused 15-mm active-tip needle based on constructor specifications. The volume of tissue coagulation from RF was calculated from measurements of the vertical diameter (Dv) and transverse diameter (Dt). Lesion shape was characterized using the ratio between Dt/Dv. Radiotherapeutics and RITA produced in vivo lesion volume of 42±10, 39±4 cm³ with a reproducible spherical shape (Dt/Dv of 1.01±0.16 and 0.97±0.1, respectively). Radionics produced in vivo RF lesions volume of 29±11 cm³ with an ovoid shape (Dt/Dv 0.88±0.09). The RF lesions with the Berchtold device could not be assessed in vivo as 5 of 8 animals died during treatment. Ex vivo RF lesions had similar volumes with each system; however, the Radiotherapeutics device produced more reproducible shaped lesions than the other systems. In our experimental study, we found no difference between expandable needle systems in vivo. Cooled needles produced slightly smaller and ovoid shape in vivo lesions.     

内镜下射频消融配合胃三联治疗慢性胃炎隆起糜烂型的临床观察

目的:探讨射频局部消融配合胃三联治疗慢性胃炎隆起糜烂型的疗效．方法:内镜下符合慢性胃炎隆起糜烂型诊断,H pylori阳性的患者106例,随机分为治疗组:射频消融 洛赛克omeprazole、阿莫西林 Amoxicillin、克拉霉素Clarithromycin(简称胃三联)治疗,对照组:单纯胃三联治疗．结果:治疗组隆起糜烂病灶平复率、临床症状有效率分别为100％和94．1％,对照组隆起糜烂病灶平复率、临床症状有效率分别为 27．2％和58．2％,优于对照组(P<0．05)．H pylori 根除率治疗组88．2％,对照组85．7％,二者之间无显著差异(P>0．05)．结论:射频局部消融配合胃三联治疗慢性胃炎隆起糜烂型疗效确切、操作简单、安全．     

3D立体放疗联合射频加温治疗中晚期肺癌300例

目的探讨X线立体定向放射治疗与内生场射频低温加热治疗中晚期肺癌的疗效。方法对300例晚期肺癌患者随机分组(各150例),分别采取3D立体分次放射(SRT)合并普通放疗(RT)和低温加热(40～43℃)治疗,有胸水者在抽取胸水的同时化学药物加生理盐水回输灌注,与单纯SRT和RT组比较。结果联合低温加热组,缓解疼痛,减少胸水,改善临床症状明显优于单纯SRT和RT组,并且改善征象快。加温组不良反应有:加温时多汗,体质虚弱者稍有烦躁、心率加快。结论射频低温加热不仅对放射治疗有协同(增敏)作用,而且对疼痛改善快,特别对有胸水的患者,可使胸水明显减少或消失。     

射频热疗辅以环丙沙星治疗慢性前列腺炎

为探讨难治性慢性前列腺炎（ＣＰｔ）的治疗方法，对７４例经不同方法治疗失败的难治性ＣＰｔ患者行前列腺射频热疗并辅以口服环丙沙星片治疗，并对治疗前后的临床症状改善情况及前列腺液镜检结果进行对照，结果除３例首次热疗后自觉症状加重而中止治疗外，余７１例完成全疗程，其中６１例治愈或有效。认为射频热疗辅以环丙沙星治疗是一种较传统方法疗效较好的治疗难治性ＣＰｔ的新方法。     

超声在冷循环射频治疗肝癌中的应用

目的探讨超声在冷循环射频治疗肝癌中的应用价值。方法105例肝癌病人,术前利用超声进行评估并据此制定治疗方案,经皮及术中射频治疗均采用超声作为引导方式,术后1周及1月进行超声复查。结果术前超声检查对治疗方案的制定起重要作用。超声也是最常用的射频引导手段。经皮和术中超声引导下射频各有所长,需根据具体情况选择。射频治疗后瘤体二维超声表现多样,部分瘤体坏死液化。能量多普勒提示肝癌的血流信号较术前减少。结论将超声技术紧密结合临床,对射频治疗肝癌病人进行全程干预,有助于冷循环射频成为更安全、更有效的肝癌治疗方法。     

经皮射频治疗肺部恶性肿瘤的螺旋CT评价

目的应用螺旋CT评价射频治疗肺部恶性肿瘤的近期疗效.方法对40例肺癌43个病灶射频治疗前、后肿瘤大小、密度的变化、肿瘤凝固性坏死的形态、范围及并发症进行观察.结果 40例肺癌射频治疗后5min90.69%(39/43)的肺癌病灶扩大,6.9%(3/43)病灶大小无变化,2.3%(1/43)病灶缩小.97.67%(42/43)病灶密度减低,2.3%(1/43)病灶密度增高.术后20例肺癌随访1～17个月,平均随访4.3个月,55%(11/20)病灶较原病灶缩小,40%(8/20)病灶较术前增大,5%(1/20)病灶大小无变化,95%(19/20)肿瘤密度减低,CT值平均减低13 Hu,5%(1/20)密度增高.结论螺旋CT可准确评价肺癌射频治疗的效果,为临床治疗提供依据.     

核磁射频系统描述及平板线圈连续烧毁的原因分析

简述核磁共振射频系统和体部线圈的作用和相互作用,描述并分析可能引起同一线圈连续烧毁的原因,提出维修方案,总结经验供同行参考。