Fast path planning in virtual colonoscopy

We propose a fast path planning algorithm using multi-resolution path tree propagation and farthest visible point. Initial path points are robustly generated by propagating the path tree, and all internal voxels locally most distant from the colon boundary are connected. The multi-resolution scheme is adopted to increase computational efficiency. Control points representing the navigational path are successively selected from the initial path points by using the farthest visible point. The position of the initial path point in a down-sampled volume is accurately adjusted in the original volume. Using the farthest visible point, the number of control points is adaptively changed according to the curvature of the colon shape so that more control points are assigned to highly curved regions. Furthermore, a smoothing step is unnecessary since our method generates a set of control points to be interpolated with the cubic spline interpolation. We applied our method to 10 computed tomography datasets. Experimental results showed that the path was generated much faster than using conventional methods without sacrificing accuracy, and clinical efficiency. The average processing time was approximately 1s when down-sampling by a factor of 2, 3, or 4. We concluded that our method is useful in diagnosing colon cancer using virtual colonoscopy.     

类风湿关节炎社区防治路径的可行性分析

目的分析社区服务中心在类风湿关节炎（RA）早期普查和疾病防治的可行性。方法选取上海浦东新区新场社区卫生服务中心健康体检人群共计1000例,首先对所有人群进行血清学指标初筛,包括抗CCP抗体、RF、CRP和ESR;对于血清学指标异常的120名体检者进行专家会诊,以确认是否为RA;同时对这部分人群进行《类风湿关节炎危险因素调查问卷》的发放与回收。结果本次研究中,120名血清异常的体检者共确诊23例RA患者,其抗CCP抗体均为阳性,其中女性19例,男性4例;发放问卷120份,回收120份。结论本研究从早期普查、快速确诊、长效随访和危险因素分析等方面初步验证了类风湿关节炎社区防治路径探索的可行性。     

Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales

We have shown that bipolar individuals have reduced quality diets, including lower intake of polyunsaturated fatty acids (PUFA). We have also reported reduced plasma levels of the n-6 PUFA, linoleic acid (LA), and the n-3 PUFA, eicosapentaenoic acid (EPA) in bipolar subjects. In the current analysis we hypothesized that LA and EPA plasma levels would mediate lower self-reported mental health and life functioning scores in bipolar subjects. In a cross-sectional study, we collected a 7-day diet record in bipolar (n = 56) and control subjects (n = 46) followed by a fasted blood draw. We used structured equation modeling path analysis to test for mediating effects of dietary intake and plasma levels of LA and EPA on self-reported mental health questionnaire scores, including the Life Functioning Questionnaire (LFQ), the Patient Health Questionnaire (PHQ9), and the Short Form Health Survey (SF12), extracting the mental health component summary score (SF12-MH). We adjusted for age, gender, psychiatric medication use, body mass index (BMI), and total caloric intake as covariates with bipolar disorder as the primary predictor. We found a significant path association from bipolar disorder to lower plasma LA levels (p = 0.03) and significant paths from plasma LA to PHQ9 (p = 0.05), LFQ (p = 0.01) and SF12-MH (p = 0.05) scores, such that lower plasma LA predicted worse outcomes. We found no significant paths from plasma EPA levels to any of the outcome measures. These findings suggest that plasma LA levels partially mediate the effect of bipolar disorder on self-reported measures of mental health and life functioning.     

大学生自杀意念的社会心理影响因素研究

目的 探讨影响大学生自杀意念的社会心理因素。方法 采用多阶段分层随机整群抽样方法,应用Beck自杀意念量表、自杀态度问卷、青少年生活事件量表、防御方式问卷、社会支持评定量表、症状自评量表(SCL-90)、简易应对方式问卷、艾森克人格问卷,对山西省普通高校一至三年级本专科大学生4882名进行现场调查,采用非条件logistic回归及通径分析探索自杀意念与各类社会心理因素之间的关系。结果 心理疾病倾向是自杀意念的主要直接影响因素,负性事件不能对自杀意念产生直接作用,只间接通过心理疾病倾向微弱地作用于自杀意念;人格等因素总是直接或间接通过应对、防御等中间变量对自杀意念产生影响作用;应对、防御、支持作为中间环节对自杀意念产生直接或间接的微小作用。结论 人格是自杀意念的基础性因素,负性生活事件对自杀意念作用虽小却起到“扳机”作用,而心理疾病倾向则是自杀意念的直接作用因素,三者依次递进有机整合最终产生自杀意念。     

高校图书馆网上图书荐购系统存在的问题与优化

阐述了高校图书馆网上荐购系统的研究现状、流程及类型,分析了当前图书荐购系统存在的主要问题,探讨了优化荐购系统的路径,包括完善荐购系统的功能、建立动态荐购知识库、增强荐购时效性、加大电子资源荐购力度及注重荐购绩效评估等。     

桂林市麻风病家庭内传染254例临床分析

目的了解桂林市麻风病家庭发病情况,为制定麻风防治规划提供科学参考。方法对2009年桂林市报告登记的1806例麻风病资料进行统计,并对其中198户麻风病人家庭内发现的254例麻风病人进行现场调查。结果 254例继发病人中,男168例(66.14%),女86例(33.86%),一个家庭有3例以上麻风病人44户(22.22%)。顺向传染144例(56.69%),平向传染82例(32.28%),逆向传染19例(7.48%),其他传染9例(3.54%)。结论麻风发病具有明显的家庭内聚集现象,顺向传染明显高于其他传染,麻风家庭等高危人群的密切监测和健康教育应成为麻风低流行地区防治工作的重点。     

Television display of bliss symbols

Resolution requirements for television display of Bliss symbols are investigated. To encode the symbols a path-direction technique is developed and compared with run length coding and the partial symbol method.     

职高生自我概念、成就目标与心理健康的关系

目的:探察职高生自我概念、成就目标及与心理健康之间的相互关系。方法:采用自我概念问卷、成就目标问卷和SCL-90对450名职高生进行问卷调查。结果:人口学变量中除年级因素外(P<0.05),是否独生子女、性别和年龄等因素对心理健康的预测作用不显著(P>0.05);越倾向成绩目标者,心理问题越多(P<0.05);越倾向于学习目标者,心理问题越少(P<0.001),但此作用受到自我概念的中介,拥有更高自我概念者,心理问题越少(P<0.001)。结论:在关注职高生的心理健康状况时,可以从自我概念和成就目标两个方面入手进行干预。     

老年缺血性脑卒中患者社会网络与认知功能的相关性研究

目的探讨老年脑卒中患者社会网络与认知功能及其各领域的相关性。方法采用简易精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)、记忆与执行筛查量表(分为MES-M和MES-E)、语言功能量表(LAST)、社会网络量表(LSWS-6)对2018年8月-2019年5月复旦大学附属上海市第五人民医院收治的141例老年脑卒中患者进行评估;采用Pearson和Spearman相关对认知功能的影响因素进行单因素分析,基于社会网络影响健康结局的理论和单因素分析结果建立结构方程模型。结果研究对象中认知障碍与轻度认知障碍发生率分别为33.3%和94.3%。路径分析显示:年龄、婚姻状况、文化程度、有氧运动、抑郁状态、神经功能缺损评分(NIHSS)等直接和(或)间接影响老年患者认知功能,社会网络在文化程度与MMSE、MoCA、MES-M之间起中介作用,中介效应值分别为0.047、0.065、0.092,社会网络在抑郁状态与MMSE之间的中介效应值为-0.105。结论脑卒中后认知障碍在老年缺血性脑卒中患者中十分常见,受多种因素影响,抑郁状态和社会网络均对认知功能有显著影响,社会网络在抑郁状态与认知功能...     

静脉路径管理在血液病患者输液中的应用研究

目的 探讨静脉路径管理在血液病患者输液中的应用效果.方法 选择2009年1-10月我院血液科患者400例,选择200例为干预组,其中普通血液病患者47例,恶性血液病患者153例;对照组200例,其中普通血液病患者49例,恶性血液病患者151例.对照组按常规输液流程进行静脉输液,干预组通过静脉路径管理制订个性化输液方案进行静脉输液,观察两组患者静脉穿刺后并发症发生率及患者输液满意度.结果 干预组静脉穿刺并发症的发生率明显低于对照组,患者静脉输液满意度有明显提高,差异有统计学意义(P<0.05).结论 对血液病患者采用个性化的输液方案,加强静脉路径管理,有助于减少患者因静脉穿刺产生的并发症,有利于血液病患者的治疗与康复,从而提高患者的满意度.