Insights into the origins of knowledge from the cognitive neuroscience of blindness

Children learn about the world through senses such as touch, smell, vision, and audition, but they conceive of the world in terms of objects, events, agents, and their mental states. A fundamental question in cognitive science is how nature and nurture contribute to the development of such conceptual categories. What innate mechanisms do children bring to the learning problem? How does experience contribute to development? In this article we discuss insights into these longstanding questions from cognitive neuroscience studies of blindness. Despite drastically different sensory experiences, behavioural and neuroscientific work suggests that blind children acquire typical concepts of objects, actions, and mental states. Blind people think and talk about these categories in ways that are similar to sighted people. Neuroimaging reveals that blind people make such judgements relying on the same neural mechanisms as sighted people. One way to interpret these findings is that neurocognitive development is largely hardwired, and so differences in experience have little consequence. Contrary to this interpretation, neuroimaging studies also show that blindness profoundly reorganizes the visual system. Most strikingly, developmental blindness enables “visual” circuits to participate in high-level cognitive functions, including language processing. Thus, blindness qualitatively changes sensory representations, but leaves conceptual representations largely unchanged. The effect of sensory experience on concepts is modest, despite the brain's potential for neuroplasticity.     

专科护士培训体验式教学理论模型的构建

目的 构建重症医学专科护士培训体验式教学理论模型.方法 以贵州省重症医学专科护士培训教学活动为基础,采用文献分析法、问卷调查法、实证研究法、经验总结法,研究重症医学专科护士培训体验式教学理论模型.结果 构建了包括四内容(教学目标、教学内容、教学形式、教学评价),四环节(危重患者护理体验、反思与分享、感悟内化、实践与应用)、三过程(基础、提高、升华)的循环上升式重症医学专科护士培训体验式教学理论模型.结论该理论模型展现了重症医学专科护士培训体验式教学的规律,为专科护士培养提供优化的教学途径.     

基于知识图谱构建和定性访谈法探析张忠德教授辨治间质性肺病临床特征与方药规律＊

目的 构建个性化知识图谱技术和定性访谈法结合，进一步挖掘张忠德教授辨治间质性肺疾病临证特征与用药规律。方法 采用回顾性分析，系统收集张忠德教授广东省中医院门诊2010年8月至2020年8月治疗间质性肺疾病病历，按照诊断标准、纳入标准、排除标准，严格筛选后，通过广东省中医院大数据挖掘团队中医药大数据智能处理与知识服务系统进行数据挖掘分析，并通过多元化视觉定性访谈法，将定量与定性分析有效结合。结果 共筛选出347首方，共141味药物，常用药物频次 ≥ 84次的药物有10味，其中党参、麦芽、黄芪、紫菀、白术等为核心用药，通过症状与药物推理知识地图显示，党参、炒麦芽、黄芪、大枣、太子参、山萸肉、巴戟天等为主要治疗用药；临证遣方用药知识关联分析，得知咳嗽、耳鸣、心悸、水肿、头痛、胸闷、恶寒等为多见，针对咳嗽，首选紫苏子、橘红、桂枝等温肺降气通阳之品等；频繁聚集显示，常用药对炒麦芽-炒白术、黄芪-党参、黄精-菟丝子、前胡-紫菀、炙枇杷叶-浙贝母等；聚类分析结果得到4组关系密切的聚类新药物组合；以脾为中轴，肺肾共扶为主的“平调五脏论”，分期阶梯辨治间质性肺疾病。结论 张忠德教授认为间质性肺疾病，虚实夹杂为多见，应从肺、脾、肾着手，采用平调五脏论分期阶梯辨治，用药配伍精简，以和为贵，以平为期。     

Investigating how electroencephalogram measures associate with delirium: A systematic review

Delirium is a common neurocognitive disorder in hospital settings, characterised by fluctuating impairments in attention and arousal following an acute precipitant. Electroencephalography (EEG) is a useful method to understand delirium pathophysiology. We performed a systematic review to investigate associations between delirium and EEG measures recorded prior, during, and after delirium. A total of 1,655 articles were identified using PsycINFO, Embase and MEDLINE, 31 of which satisfied inclusion criteria. Methodological quality assessment was undertaken, resulting in a mean quality score of 4 out of a maximum of 5. Qualitative synthesis revealed EEG slowing and reduced functional connectivity discriminated between those with and without delirium (i.e. EEG during delirium); the opposite pattern was apparent in children, with cortical hyperexcitability. EEG appears to have utility in differentiating those with and without delirium, but delirium vulnerability and the long-term effects on brain function require further investigation. Findings provide empirical support for the theory that delirium is a disorder of reduced functional brain integration.     

The triage-function of a psychosomatic liaison-service for gynecological patients

The psychosomatic psychotherapeutic consultation liaison (CL)-service for gynecological patients at the Vienna University has been evaluated. Research interest focused on success and failure of the initial interview, conceptualized for a specific clientele. The interview has a triage function for treatment planning. By the type of treatment that was applied, patients were divided into three groups: Group A, patients with one single contact with the unit; Group B, patients who were referred to external psychotherapy; Group C, patients who were treated with short-term psychoanalytic psychotherapy as offered by the service unit. The drop-outs figured as Group D. The questionnaires completed by the patients at the first consultation and 6 months after their final contact with the clinic covered socio-demographic data, ego functions; the motivation for psychotherapy, a complaints list and finally, at the second contact only, an individual retrospective judgement concerning personal consequences of the consultation. Patients needs in CL-seruices call for quick decisions, which therapeutic measure would be most adequate. An experienced clinician's decision is based on several circumstances: individual feeling of suffering therapy-motivation and ego-strength, as well as social and demographic facts. Comparing groups with different therapeutic recommendations showed that the psychometric tests discriminated well between these four groups and thus the validity of the clinical recommendation has been confirmed.     

诊断学教案书写体会

教案书写是教师上课的总体设计和思路的书面反映，是高质量课堂教学的保障。文章结合作者自己的诊断学教学实践，从教学目标、重点难点、教学方法、教学过程、课后记五个方面总结了教案书写的心得体会。     

医院优质护理服务综合策略体系的构建

目的:构建医院优质护理服务综合策略体系。方法:通过文献资料法、理论分析法及Delphi法初步拟定医院优质护理服务综合策略体系。结果:专家咨询的权威程度系数为0.89,判断系数为0.87,熟悉程度为0.90;最终确定的医院优质护理服务综合策略体系包括一级指标4个、二级指标16个,其专家接受度均>80%。结论:用Delphi法构建的医院优质护理服务综合策略体系具有较高的科学性和可靠性,对医院优质护理服务实践具有重要意义。     

中医辨证疗法配合病症检验的体会

目的：分析中医辨证疗法配合病症检验的应用情况。方法：共收录2012年6月-2013年6月的40例资料。40例分为观察组、对照组，每组20例。观察组采用中医辨证疗法，对照组采用常规治疗与检验方法。结果：临床采用中医辨证疗法配合病症检验，治疗总有效率达95%；与对照组相比差异性显著（P〈0.01）。结论：中医辨证疗法效果优、见效快，值得临床推广。     

张有民奇治法治疗淋证

张有民主任仿《石室秘录·奇治法》治疗淋证,认为本病的治疗目的在于温肾阴,清膀胱湿热,疏肝理脾,行气活血。用原方加减治疗各种淋病,取得良好效果。