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991.
目的 本试验拟通过对胃癌组织中微血管的数量、血管分布方式的检测,探讨其与肝转移的关系。方法 收集胃癌石蜡标本75例,其中肝转移29例,采用兔抗人第Ⅷ因子相关抗体,SABC免疫组化方法,在200倍镜下计数每个病例癌组织中的血管数,以均值作为区分高、低血管组的标准。按血管在癌组织中的分布方式分为:肿瘤内型和间质型。检测,胃癌组织中的微血管数量和分布方式,比较与肝转移的关系。结果 全组病例的微血管数范围 相似文献
992.
Fermín García-Muñoz Rodrigo Loida García Cruz Gloria Galán Henríquez Lourdes Urquía Martí Sonia Rivero Rodríguez Alfredo García-Alix Josep Figueras Aloy 《Jornal de pediatria》2019,95(1):41-47
Objective
To know the distribution of births of very low birth weight infants by day of the week, and whether this distribution affects the morbidity and mortality in this group of patients.Methods
This was a retrospective analysis of data collected prospectively in the Spanish SEN1500 network (2002–2011). Outborn infants, patients with major congenital anomalies, and those who died in the delivery room were excluded. Births were grouped into “weekdays” and “weekends.” A multivariate logistic regression analysis was conducted to evaluate the independent effect of the birth moment on outcomes, and Cox regression for survival.Results
Out of a total of 27,205 very low birth weight infants born at and/or admitted to the participating centers, 22,961 (84.4%) met inclusion criteria. A reduction of 24% in the number of births was observed during the “weekends” compared with “weekdays”. In the raw analysis, patients born on weekends exhibited higher morbidity and mortality (mortality rate: 14.2% vs. 16.5%, p < 0.001), but differences were no longer significant after adjusting for confounding factors.Conclusions
The present results suggest that current care practices reduce the proportion of births during the weekends and tend to cluster some high-risk births during this period, increasing crude morbidity and mortality. However, after adjusting for confounding factors, the differences disappear, suggesting that overall care coverage in these centers is appropriate. 相似文献993.
J. Grignoux Q. Durand-Moreau N. Vongmany S. Brunel J.-D. Dewitte 《European annals of otorhinolaryngology, head and neck diseases》2019,136(1):7-12
Objectives
As part of the 2014–2019 cancer plan and in order to improve our knowledge of work-related cancers, we analysed the work-related laryngeal cancer risk situations identified in the French national occupational disease surveillance and prevention network (rnv3p) from 2001 to 2016.Material and methods
This study focused on cases of work-related laryngeal cancer, which the expert physician considered to be directly related to exposure (intermediate or strong causal relationship). Demographic data, occupational exposure circumstances (hazards, occupation, business sector), non-occupational risk factors and the occupational physician's opinion concerning notification as an occupational disease were analysed.Results
Two hundred forty-four cases of laryngeal cancer were registered between 2001 and 2016. One hundred and forty seven cases were considered to be work-related, with an intermediate or strong causal relationship in 87 cases. This exclusively male population had a median age of 59 years. Ninety-seven different forms of exposure were identified, including asbestos in 78 cases. The main business sectors concerned were specialized construction (14 cases) and metallurgy (7 cases). Occupational disease notification was recommended in 60 patients, corresponding to asbestos exposure in 80% of cases.Conclusions
Asbestos is the laryngeal cancer risk factor most commonly reported in the network from 2001 to 2016. This study confirms the role of asbestos in laryngeal carcinogenesis. Laryngeal cancer may therefore need to be compensated as an occupational disease in France, as in other European countries. 相似文献994.
必扑杀蟑饵剂连锁灭蟑效果观察 总被引:2,自引:2,他引:0
目的 观察连锁杀蟑饵剂在不同条件下的连锁灭蟑效果,并探讨其应用前景。方法 参照国标测试饵剂药效方法。利用试虫的“有毒”粪便、“有毒”虫尸,作为下一步实验试虫的食物,分别测试若虫、成虫的连锁实验,并测试有、无外源食物竞争情况下的连锁作用。结果 必扑杀蟑饵剂药效达到国标B级标准,在无外源食物竞争情况下,对若虫、成虫显示出良好连续杀灭效果,但若有外源食物竞争,则这一效果明显下降。结论 连锁杀蟑饵剂有连锁灭蟑效果。 相似文献
995.
Michelle Mckerral Pierre Lachapelle Ph.D. Julie Benoit 《Documenta ophthalmologica. Advances in ophthalmology》1992,79(2):177-185
We investigated the effect of reduced luminance and increased scatter on the pattern visual evoked potential and eye-hand reaction time evoked to a check size of 0.5° in 10 normal subjects. Data analysis indicated that a reduction in luminance as well as an increase in scatter caused a statistically significant increase in the peak time of the pattern visual evoked potential P100 wave. The reaction time, however, was not significantly affected by the initial 0.9-log unit attenuation of the stimulus luminance or the 0.3 scatter filter. Further attenuation of luminance or increase of scatter also yielded statistically significant increases. Our results suggest that the reaction time is less affected by a reduction in luminance or an increase in scatter of a 0.5° stimulus than the pattern visual evoked potential is and therefore represents a more reliable test to assess visual function, especially in the presence of medial opacities, which are known to reduce luminance and produce scatter. 相似文献
996.
影响老年髋部骨折手术治疗效果的因素分析 总被引:6,自引:0,他引:6
目的 探讨影响老年髋部骨折手术治疗效果的因素。方法 回顾性分析我院 1998年 1月~ 2 0 0 2年 1月 187例确诊为老年髋部骨折患者的临床资料 ,分析各种因素对手术治疗结果的影响。结果 患者年龄、伤前基本生活能力 (ADL)、行走能力、术前健康状况的美国麻醉学会 (ASA)分级、术后并发症等对治疗结果有明显影响 (P <0 .0 5 ) ;而性别、骨折类型、手术时间、手术方法等无明显影响 (P >0 .0 5 )。结论 术前ASA分级可很好预示老年髋部骨折术后死亡率 ,伤前ADL是影响术后功能康复的最主要因素。 相似文献
997.
998.
B. F. Feldman 《Comparative Haematology International》1996,6(1):42-45
Detailed examination of the records of 57 dogs referred to our clinic with the diagnosis of immunemediated haemolytic anaemia was accomplished. Only untreated dogs or dogs who had only received supportive therapy were included in the study group comprising 30 male dogs and 27 female dogs. Age distribution followed the general age distribution of our patient population. There was no within-breed sex or age predilection. The youngest dog was 11 months of age and the oldest dog was 13 years of age. Overall mortality rate among the study population was 51% (29 dogs). Certain canine breeds were over-represented in this study and these same breeds had high mortality rates. Included were 11 cocker spaniels (19%; 82% mortality rate, 9 of 11 dogs), nine dogs with terrier in their name (16%; 78% mortality rate, 7 of 9 dogs), six German shepherds (11%; 50% mortality rate, 3 of 6 dogs), five doberman pinschers (9%; 60% mortality rate, 3 of 5 dogs), and five miniature schnauzers (9%; 60% mortality rate, 3 of 5 dogs). Immune-mediated haemolytic anaemia was considered secondary to hepatic disease in 16 dogs (28%), septicaemia in 10 dogs (18%) and neoplasia in six dogs (11%), i.e. signs and data supporting these processes were reported to have preceded anaemia. A total of 29 dogs (51%) also had thrombocytopenia (platelet counts less than 60000 cells/µl), eight (14%) dogs had major venous thrombosis, eight (14%) dogs had associated disseminated intravascular coagulation, and 24 (42%) of the dogs had evidence of renal disease — proteinuria and cylinduria. About 35% (20 dogs) of the patients were treated from June to August, and 63% (36 dogs) of the patients were direct antiglobulin positive (immunoglobulin G with or without complement). A variety of red cell morphological changes were observed including stomatocytes, bowl forms, knizocytes, schistocytes and spherocytes. Spherocytes were observed in 11 dogs (19%). Absolute reticulocytosis was observed in 26 dogs (46%). A variety of treatment combinations including glucocorticoids, azathioprine, cyclophosphamide, anabolic steroids, heparin, intravenous human gamma globulin, and blood component therapy were used without identifiable success associated with any given protocol. 相似文献
999.
1000.
应用EYLL指标分析了泰安市疾病监测点1985、1986两年的死因资料,并计算了男、女居民两年的平均期望寿命,PYLL下降与期望寿命提高相一致。通过PYLL指标与其它死亡指标的比较,笔者认为PYLL指标来强调各种死亡原因引起居民“早死”造成寿命减少这一点上,优于其它指标。PYLL可作为评价居民健康水平较好的定量指标。 相似文献