全文获取类型
收费全文 | 2510篇 |
免费 | 124篇 |
国内免费 | 63篇 |
专业分类
儿科学 | 5篇 |
妇产科学 | 448篇 |
基础医学 | 419篇 |
口腔科学 | 9篇 |
临床医学 | 235篇 |
内科学 | 29篇 |
皮肤病学 | 9篇 |
神经病学 | 9篇 |
特种医学 | 50篇 |
外国民族医学 | 3篇 |
外科学 | 30篇 |
综合类 | 559篇 |
预防医学 | 102篇 |
眼科学 | 1篇 |
药学 | 135篇 |
2篇 | |
中国医学 | 24篇 |
肿瘤学 | 628篇 |
出版年
2024年 | 1篇 |
2023年 | 11篇 |
2022年 | 30篇 |
2021年 | 34篇 |
2020年 | 48篇 |
2019年 | 26篇 |
2018年 | 27篇 |
2017年 | 40篇 |
2016年 | 60篇 |
2015年 | 54篇 |
2014年 | 82篇 |
2013年 | 113篇 |
2012年 | 106篇 |
2011年 | 167篇 |
2010年 | 128篇 |
2009年 | 150篇 |
2008年 | 160篇 |
2007年 | 186篇 |
2006年 | 160篇 |
2005年 | 137篇 |
2004年 | 119篇 |
2003年 | 100篇 |
2002年 | 96篇 |
2001年 | 71篇 |
2000年 | 64篇 |
1999年 | 53篇 |
1998年 | 36篇 |
1997年 | 43篇 |
1996年 | 46篇 |
1995年 | 41篇 |
1994年 | 27篇 |
1993年 | 37篇 |
1992年 | 32篇 |
1991年 | 34篇 |
1990年 | 28篇 |
1989年 | 19篇 |
1988年 | 16篇 |
1987年 | 14篇 |
1986年 | 8篇 |
1985年 | 18篇 |
1984年 | 11篇 |
1983年 | 18篇 |
1982年 | 9篇 |
1981年 | 12篇 |
1980年 | 7篇 |
1979年 | 12篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 1篇 |
排序方式: 共有2697条查询结果,搜索用时 15 毫秒
51.
目的探讨间苯三酚在产程活跃期伴宫颈水肿应用的影响。方法选择足月单胎头先露的初产妇,无妊娠合并症和胎位异常,于活跃期宫口开大3~4cm,伴宫颈水肿、坚韧、宫口扩张延缓90例,随机分为观察组和对照组各45例,观察组:间苯三酚40mg宫颈注射+40mg静脉注射,对照组:地西泮10mg静脉注射,观察两组对产程变化及母儿影响。结果两组于用药后至宫口开全时间,用药4h宫口扩张及宫颈水肿消退比较,两组差异有统计学意义(P<0.01),而两组产后出血量,分娩方式及新生儿Apgar评分差异无统计学意义(P>0.05)。结论间苯三酚能显著加速宫口扩张,缩短产程,对母儿无不良影响。 相似文献
52.
53.
54.
目的 探讨液基涂片细胞学(TCT)检查联合高危型人乳头瘤病毒(HPV)检测在宫颈病变诊断中的价值.方法 收集500例宫颈脱落细胞标本,采用宫颈细胞学检查、HPV DNA检测或2种方法联合检查后,选择所有的HPV阳性和TCT报告为意义不明确的不典型鳞状细胞(ASC-US)以上者,均通过阴道镜取活检,以组织学诊断为金标准,比较宫颈细胞学检查、HPV DNA检测及以上2种方法联合检查与组织病理学诊断的符合率、灵敏度和特异度.结果 313名TCT报告为ASC-US以上者,与组织病理学诊断的符合率为82.4%.268名检测结果为HPV DNA阳性的女性与组织病理学诊断的符合率为77.2%.2种方法联合检查251名女性,与组织病理学诊断的符合率为92.0%.TCT联合HPV DNA检测与单纯HPV DNA检测比较,差异有统计学意义(P<0.01).TCT联合HPV DNA检测与单纯TCT比较,差异有统计学意义(P<0.01).HPV DNA检测诊断宫颈癌的灵敏度为83.8%,特异度为75.9%,TCT检测诊断宫颈癌的灵敏度为93.5%,特异度为75.4%,TCT检查联合HPV DNA检测诊断宫颈癌的灵敏度为96.3%,特异度为87.5%.结论 TCT联合HPV DNA检测在宫颈病变筛查中比单纯TCT或单纯HPV DNA检测更具有实用价值. 相似文献
55.
Timely follow‐up of positive cancer screening results: A systematic review and recommendations from the PROSPR Consortium
下载免费PDF全文
![点击此处可从《CA: a cancer journal for clinicians》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Chyke A. Doubeni MD MPH Nicole B. Gabler PhD MPH MHA Cosette M. Wheeler PhD Anne Marie McCarthy PhD Philip E. Castle PhD MPH Ethan A. Halm MD MPH Mitchell D. Schnall MD PhD Celette S. Skinner PhD Anna N. A. Tosteson ScD Donald L. Weaver MD Anil Vachani MD Shivan J. Mehta MD MBA Katharine A. Rendle PhD MSW MPH Stacey A. Fedewa PhD Douglas A. Corley MD PhD Katrina Armstrong MD 《CA: a cancer journal for clinicians》2018,68(3):199-216
Timely follow‐up for positive cancer screening results remains suboptimal, and the evidence base to inform decisions on optimizing the timeliness of diagnostic testing is unclear. This systematic review evaluated published studies regarding time to follow‐up after a positive screening for breast, cervical, colorectal, and lung cancers. The quality of available evidence was very low or low across cancers, with potential attenuated or reversed associations from confounding by indication in most studies. Overall, evidence suggested that the risk for poorer cancer outcomes rises with longer wait times that vary within and across cancer types, which supports performing diagnostic testing as soon as feasible after the positive result, but evidence for specific time targets is limited. Within these limitations, we provide our opinion on cancer‐specific recommendations for times to follow‐up and how existing guidelines relate to the current evidence. Thresholds set should consider patient worry, potential for loss to follow‐up with prolonged wait times, and available resources. Research is needed to better guide the timeliness of diagnostic follow‐up, including considerations for patient preferences and existing barriers, while addressing methodological weaknesses. Research is also needed to identify effective interventions for reducing wait times for diagnostic testing, particularly in underserved or low‐resource settings. CA Cancer J Clin 2018;68:199–216 . © 2018 American Cancer Society . 相似文献
56.
目的检测子宫颈癌患者放疗前后血清铜、锌的变化,检测子宫颈癌患者与正常人血清铜、锌水平的比较。材料与方法采用三电极直流等离子原子发射光电直读光谱仪法检测。结果子宫颈鳞癌患者血清铜(SCu)、铜锌比值(Cu/Zn)显著高于正常对照组(P<0.001),Ⅲ期患者又显著高于Ⅱ期患者(P<0.001);放疗后癌灶完全消退者(CD)SCu、Cu/Zn明显下降(P<0.01);部分消退者(PD)二值仍处于高水平。结论:SCu和Cu/Zn可以检测放疗疗效,估计预后,有一定临床意义。 相似文献
57.
58.
HPV genotyping in cervical cancer in Northern Thailand: adapting the linear array HPV assay for use on paraffin-embedded tissue 总被引:3,自引:1,他引:2
Siriaunkgul S Suwiwat S Settakorn J Khunamornpong S Tungsinmunkong K Boonthum A Chaisuksunt V Lekawanvijit S Srisomboon J Thorner PS 《Gynecologic oncology》2008,111(3):555-560
ObjectiveThe objective of this study was to review our experience with abdominal radical trachelectomy in patients with early-stage cervical cancer.MethodsWe performed a retrospective review of all patients who underwent an abdominal radical trachelectomy at the Instituto de Cancerologia—Clinica las Americas in Medellin, Colombia, between April 2002 and January 2008. Data collected included age, stage, histopathologic subtype, tumor size, evidence of lymph-vascular space invasion, estimated blood loss, number of perioperative blood transfusions, number and disease status of lymph nodes removed, disease status of surgical specimen, length of hospital stay, intraoperative and postoperative complications, follow-up time, and fertility outcomes.ResultsFifteen patients underwent an abdominal radical trachelectomy during the study period. The median patient age was 30 years (range, 25–38). Three patients had stage IA2 and 12 had stage IB1 cervical cancer. Eleven patients had squamous cell carcinoma and 4 had adenocarcinoma. Thirteen patients were diagnosed by cervical conization and 2 by colposcopically directed biopsy. All patients had tumors smaller than 2 cm. The median estimated blood loss was 400 ml (range, 200–1000). The median surgical time was 265 min (range, 210–330). The median number of units of packed red blood cells transfused per patient was 2. The median number of lymph nodes removed was 26 (range, 11–48). The median length of hospitalization was 3 days (range, 2–7). The median follow-up time was 32 months (range, 5–32). There was 1 intraoperative complication and 6 postoperative complications in 4 patients. No patient has had a recurrence. Three patients were able to conceive spontaneously; 1 delivered at 31 weeks' gestation, and 2 delivered at term.ConclusionAbdominal radical trachelectomy is feasible and can be performed safely in a developing country in well-selected patients with early cervical cancer who wish to preserve their fertility. 相似文献
59.
Kashanian M Fekrat M Naghghash S Ansari NS 《The journal of obstetrics and gynaecology research》2008,34(1):47-50
AIM: To compare the effect of extra-amniotic normal saline solution infusion on its own, and in combination with dexamethasone on the ripening of the cervix and induction of labor. METHODS: A double-blind randomized clinical trial study was performed at Akbar Abadi Teaching Hospital in Tehran, Iran, between March 2002 and March 2003 on 84 pregnant women at a gestational age of 40 weeks or more, and with a Bishop score 相似文献