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111.
A. Neumann M. Schlesier H. Schneider A. Vogt H. H. Peter 《Rheumatology international》1989,9(3-5):237-241
Summary Using a limiting dilution system, frequencies of Borrelia burgdorferi-reactive T cells were determined in the blood and synovial fluid of four patients with chronic Lyme arthritis (LA), one patient with acrodermatitis chronica atrophicans (ACA), two patients with other inflammatory joint diseases, and two healthy individuals. B. burgdorferi-reactive precursor T cells ranged from 1/750 to 1/8 220 in case of LA and ACA patients and from 1/820 to 1/31 400 in case of controls. In vivo activated B. burgdorferi-reactive T cells were almost absent in control subjects. With one exception, they were detected in LA patients at frequencies ranging from 1/1 300 to 1/15 400. Interestingly, even after successful antibiotic therapy of LA patients, similar frequencies of in vivo activated B. burgdorferi-reactive T cells were observed in the peripheral blood, provided that low cell concentrations were used for culture. At higher cell numbers, the fraction of B. burgdorferi-reactive T cells apparently dropped, suggesting regulatory phenomena. 相似文献
112.
J. Stephen Huff MD Scott A. Syverud MD Mary Anne Tucci MD 《Academic emergency medicine》1995,2(8):751-756
A previously healthy 32-year-old man presented to the ED in complete heart block. Ischemic, infectious, and inflammatory conditions were considered in the differential diagnosis. Management options for complete heart block, the etiology of heart block in young adults, and treatment guidelines are reviewed. 相似文献
113.
114.
福建莱姆病蜱媒及其宿主调查研究 总被引:6,自引:0,他引:6
1990~1995年,对福建莱姆病疫区的蜱媒及其宿主进行调查,查出蜱类19种,宿主包括家野鼠类、野猪、野兔、獾、山羊等野生动物和狗、牛等家畜。从粒形硬蜱、台湾角血蜱和社鼠、褐家鼠分离出莱姆病病原体,粒形硬蜱可能是福建莱姆病的主要蜱媒。 相似文献
115.
S. Avanzi G. Messa A. Marbini G. Pavesi F. Granella 《The Italian Journal of Neurological Sciences》1998,19(2):81-85
Lyme disease is an infectious disease caused by the spirocheteBorrelia burgdorferi. The course of the disease is divided into three stages, the second of which may include various types of peripheral nervous
system disturbances. We report the case of a patient with persistent deficits caused by the prevalent involvement of the sciatic
nerve, confirmed by electrophysiological and neuropathological findings. The most significant bioptic results were axonal
degeneration and perivascular inflammation. Damage to a single peripheral nerve as the dominant clinical expression during
the course of Lyme disease is an unusual finding that has been rarely described in the literature. 相似文献
116.
117.
V. Seriburi N. Ndukwe Z. Chang M.E. Cox G.P. Wormser 《Clinical microbiology and infection》2012,18(12):1236-1240
Although it is known that two-tier serologic testing for Lyme disease may be associated with false positive results on the IgM immunoblot, this problem has never been systematically studied in the clinical practice setting. In a retrospective investigation of patients referred to the private adult practice of an Infectious Diseases physician for possible for Lyme disease, 50 of 182 patients (27.5%, 95% CI: 21.1-34.6) were found to have a false positive IgM immunoblot. 78.0% of these patients had received unnecessary antibiotic therapy. False positive results were not restricted to any single commercial laboratory. Research on alternative testing strategies that eliminate the IgM immunoblot entirely is warranted. 相似文献
118.
《Neuro-ophthalmology (Aeolus Press)》2013,37(2):111-114
A 57-year-old man was referred for a painful acute inferior visual field defect in his right eye. Fundus examination of the right eye revealed diffuse optic disc oedema compatible with a papillitis. Cerebrospinal fluid (CSF) findings were consistent with lymphocytic meningitis, and serologic tests for Lyme disease were positive in both serum and CSF. After treatment with ceftriaxone and bolus of methylprednisolone, right eye inferior altitudinal visual field defect persisted despite resolution of papillitis, and fundus examination disclosed a superior optic atrophy in the right eye. To our knowledge, it is the first reported case of a unilateral Lyme optic neuritis occurring simultaneously to neuroborreliosis and further complicated by non-arteritic anterior ischaemic optic neuropathy. 相似文献
119.
Levent Akduman Michael Feiner John S. Pollack Henry J. Kaplan 《Ocular immunology and inflammation》2013,21(2):97-102
AIMS/BACKROUND: To report progressive changes in the fluorescein and indocyanine green angiograms of a patient with acute idiopathic maculopathy (AIM). METHODS: Over a two-year period, the patient underwent repeated ophthalmoscopic examinations and fluorescein (FA) and indocyanine green (ICG) angiography. RESULTS: The patient presented with subretinal neovascularization in his right eye. He developed recurrences after laser photocoagulation and surgical removal of the neovascular complex. One year later, he experienced a sudden loss of vision in his left eye with a maculopathy consistent with AIM. The maculopathy resolved after two weeks with poor vision. During the acute stage, FA showed lobular hyperfluorescence in the early phase and pooling in the late phase of the angiogram. In the resolved stage of the disease, FA showed irregular window defects and blockage. ICG revealed late hyperfluorescence of the macula in the acute stage. In the resolved stage of the disease, early hypofluorescence was noted in the ICG, which persisted throughout the late phase. CONCLUSION: This patient had poor vision in his right eye as a result of subretinal retinal neovascularization and poor vision in his left eye from a severe form of AIM. FA and ICG differed markedly during the acute and resolved stages of AIM. All cases of idiopathic subretinal neovascularization should be carefully evaluated to exclude AIM as the primary disease. 相似文献
120.