全文获取类型
收费全文 | 5432篇 |
免费 | 391篇 |
国内免费 | 91篇 |
专业分类
耳鼻咽喉 | 66篇 |
儿科学 | 171篇 |
妇产科学 | 103篇 |
基础医学 | 360篇 |
口腔科学 | 224篇 |
临床医学 | 630篇 |
内科学 | 959篇 |
皮肤病学 | 294篇 |
神经病学 | 428篇 |
特种医学 | 131篇 |
外科学 | 534篇 |
综合类 | 501篇 |
预防医学 | 909篇 |
眼科学 | 64篇 |
药学 | 214篇 |
中国医学 | 195篇 |
肿瘤学 | 131篇 |
出版年
2024年 | 7篇 |
2023年 | 203篇 |
2022年 | 332篇 |
2021年 | 437篇 |
2020年 | 361篇 |
2019年 | 397篇 |
2018年 | 363篇 |
2017年 | 240篇 |
2016年 | 163篇 |
2015年 | 155篇 |
2014年 | 383篇 |
2013年 | 376篇 |
2012年 | 271篇 |
2011年 | 322篇 |
2010年 | 223篇 |
2009年 | 215篇 |
2008年 | 221篇 |
2007年 | 190篇 |
2006年 | 164篇 |
2005年 | 154篇 |
2004年 | 94篇 |
2003年 | 110篇 |
2002年 | 72篇 |
2001年 | 59篇 |
2000年 | 53篇 |
1999年 | 64篇 |
1998年 | 45篇 |
1997年 | 42篇 |
1996年 | 36篇 |
1995年 | 31篇 |
1994年 | 19篇 |
1993年 | 15篇 |
1992年 | 13篇 |
1991年 | 5篇 |
1990年 | 15篇 |
1989年 | 9篇 |
1988年 | 7篇 |
1987年 | 3篇 |
1986年 | 4篇 |
1985年 | 8篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1980年 | 3篇 |
1978年 | 2篇 |
1976年 | 3篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1973年 | 2篇 |
排序方式: 共有5914条查询结果,搜索用时 31 毫秒
21.
22.
Tim Elliott Marc Bonneville Juan Carlos Zúiga-Pflücker Paul R. Walker David Essayan Nicolas Glaichenhaus Anna Vyakarnam Jean-Laurent Casanova Yang Liu Hugh Auchincloss Jr Gerry Waneck Christian LeGuern Cezmi Akdis Allison Green 《Current opinion in immunology》2002,14(6):673
A selection of interesting papers that were published in the two months before our press date in major journals most likely to report significant results in immunology. 相似文献
23.
西文介绍了综合效益评价中指标的逐步筛选及其假设检验方法,用该法选出的指标具有独立性强、代表性好的优点。同是分析处理了全国34家县级医院的投入指标,从中筛选出5个指标参与评价。 相似文献
24.
Comparison of the APACHE III, APACHE II and Glasgow Coma Scale in acute head injury for prediction of mortality and functional outcome 总被引:1,自引:0,他引:1
Objectives: This study examines the efficacy of the predicting power for hospital mortality and functional outcome of three different
scoring systems for head injury in a neurosurgical intensive care unit (NICU).
Design: On the day of admission, data were collected from each patient to compute the Acute Physiology, Age, and Chronic Health
Evaluation (APACHE) II and III, and Glasgow Coma Scale (GCS) scores. Hospital mortality was defined as the deaths of patients
before discharge from hospital. Early mortality was defined as death before the 14th day after admission. Late mortality was
defined as death after the 15th day from admission. Functional outcome was evaluated by Index of Independence in Activities
of Daily Living (Index of ADL).
Setting: An 8-bed NICU in a 1270-bed medical center in Taichung Veterans General Hospital.
Patients and participants: Two hundred non-selected patients with acute head injury were included in our study in a consecutive period of 2 years.
Patients less than 14 years old were not included.
Interventions: None.
Measurements and results: Sensitivity, specificity and correct prediction outcome were measured by the chi-square method in three scoring systems.
The Youden index was also obtained. The best cut-off point in each scoring system was determined by the Youden index. The
difference in Youden index was calculated by Z score. A difference was also considered if the probability value was less than
0.05. The area under Receiver Operating Characteristic (ROC) curve was computed. Then the area under ROC of each scoring system
was compared by Z score. There was statistical significance if p was less than 0.05. For prediction of hospital mortality, the best cut-off points are 55 for APACHE III, 17 for APACHE II
and 5 for GCS. The correct prediction outcome is 82.4% in APACHE III, 78.4% in APACHE II and 81.9% in the GCS. The Youden
index has best cut-off points at 0.68 for APACHE III, 0.59 for APACHE II, and 0.56 for GCS. The area under Receiver Operating
Characteristic (ROC) curve is 0.90 in the APACHE III, 0.84 in the APACHE II and 0.86 in the GCS. There are no statistical
differences among APACHE III and II, and GCS in terms of correct prediction outcome, Youden Index and the area under the ROC
curve. Other physiological variables excluding GCS in APACHE III and II (AP III-GCS, AP II-GCS) have less statistical value
in the determination of mortality for acute head injury. For the prediction of late mortality, APACHE III and II yield significantly
better results in the area under the ROC curve, correct prediction and Youden index than those of GCS. Other physiological
variables (AP III-GCS and AP II-GCS) play an important role in the prediction of late mortality in APACHE scores. For prediction
of the functional outcome of surviving patients with acute head injury, the APACHE III yields the best results of correct
prediction outcome, Youden index and the area under the ROC curve.
Conclusion: The APACHE III and II may not replace the role of GCS in cases of acute head injury for hospital or early mortality assessment.
But for prediction of the late mortality, the APACHE III and II have better accuracy than GCS. Other physiological variables
excluding GCS in the APACHE system play a crucial contribution for late mortality. GCS is simple, less time-consuming and
economical for patients with acute head injury for the prediction of hospital and early mortality. The APACHE III provides
better prediction for severe morbidity than GCS and APACHE II. Therefore, the APACHE III provides a good assessment not only
for hospital and late mortality, but also for functional outcome.
Received: 22 May 1995 Accepted: 2 September 1996 相似文献
25.
目的 探索一种无创性的牙龈出血检测方法--龈沟液隐血试验(GCFobt),并分析牙龈出血与微生物之间的内在联系。方法 用隐血试纸进行102例唾液标本的唾液隐血(Sobt)检查,1600个位点的GCFobt、牙龈出血指数(SBI)、探诊深度(PD)检测,分别对79、32个龈下细菌标本作涂片检查和厌氧培养,分析临床指数与龈下细菌的关系。结果 GCFobt具较高灵敏度(68.05)和特异度(80.5%),较Sobt更能说明局部牙周炎症状况,与SBI有非常显著相关关系(P<0.001);GCFobt阳性与阴性部位螺旋体、杆菌、球菌百分含量有非常显著差异(P<0.001);在0与3之间黑色菌检出率有非常显著差异(P<0.01),在0与2、3之间梭杆菌检出率有显著差异(P<0.05)。结论 GCFobt是一种快速、简便、无创伤的检测牙龈出血新方法,可以作为牙周病临床检查的一项客观指标。 相似文献
26.
27.
目的 探讨脊柱源性心律紊乱的主要发病部位。方法 对13例脊柱病变引发的心律紊乱,主要以纠正上胸段错位为主,采用理筋、整脊和功能锻炼治疗。结果 经治疗均临床治愈,随访半年以上无复发。结论 脊源性心律紊乱主要部位在胸椎。 相似文献
28.
29.
中医疲劳术语整理研究 总被引:9,自引:0,他引:9
以疲劳术语系列中的“倦类”为代表进行释义并阐述了整理疲劳术语的意义的目的。其意义和目的为:阐明中医疲劳的病因,病机,规范描述疲劳的术语,为探讨中医抗疲劳及调治亚健康的方药提供线索与依据。 相似文献
30.
It has been suggested that apparent diffusion coefficient (ADC) contrast can be sensitive to cerebral blood flow (CBF) changes during brain activation. However, current ADC imaging techniques have an inherently low temporal resolution due to the requirement of multiple acquisitions with different b-factors, as well as potential confounds from cross talk between the deoxyhemoglobin-induced background gradients and the externally applied diffusion-weighting gradients. In this report a new method is proposed and implemented that addresses these two limitations. Specifically, a single-shot pulse sequence that sequentially acquires one gradient-echo (GRE) and two diffusion-weighted spin-echo (SE) images was developed. In addition, the diffusion-weighting gradient waveform was numerically optimized to null the cross terms with the deoxyhemoglobin-induced background gradients to fully isolate the effect of diffusion weighting from that of oxygenation-level changes. The experimental results show that this new single-shot method can acquire ADC maps with sufficient signal-to-noise ratio (SNR), and establish its practical utility in functional MRI (fMRI) to complement the blood oxygenation level-dependent (BOLD) technique and provide differential sensitivity for different vasculatures to better localize neural activity originating from the small vessels. 相似文献