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目的 调查尿路造口患者出院后自护能力的现状并分析其影响因素,旨在为该类患者自护能力的干预性研究提供依据.方法 于2019年6—9月选取门诊就诊的尿路造口患者为调查对象,采用一般资料调查表、造口自我护理量表-早期版(SSCS-ESV)、中文版造口接受度问卷、自尊量表、社会影响量表(SIS)进行调查.结果 共收回有效问卷1... 相似文献
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Background and ObjectiveThe incidence of incision infection after lung transplantation is prominently high which affect the prognosis. Summarizing the risk factors related to incision infection after lung transplantation contribute to the control of incision infection by pre-controlling the risk factors. The objective is to summarize risk factors related to wound infection after lung transplantation.MethodsPubMed was used to research the literature relating to the risk factors to incision infection after lung transplantation through 1990 to 2022. The retrieval strategy were Medical Subject Heading (MeSH) terms combined entry terms. Two researchers conducted the literature retrieval independently. Two researchers independently evaluate the quality of the literature and summarize the indicators.Key Content and FindingsA total of 98 researches were collected from PubMed and 8 articles described the related risk factors of incision infection after lung transplantation. All of the 8 articles were retrospective studies, of which 4 articles were grouped by the delayed chest closure (DCC) execution and the other 4 articles were grouped by the surgical site infection (SSI) occurred. Two articles performed multivariate regression analysis to determine the independent risk factors of SSI after lung transplantation and the other 6 articles compared the SSI rate in different patients population. The integrated results showed that bronchoalveolar lavages (BALs), smoking status, body mass index (BMI), diabetes, operation duration, thoracic drainage tube placement time and DCC were related to the SSI after lung transplantation.ConclusionsBALs, smoking status, BMI, diabetes, operation duration, thoracic drainage tube placement time and DCC were related to the SSI after lung transplantation. 相似文献
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bFGF与EGF诱导BMSCs向神经干细胞分化的观察 总被引:3,自引:0,他引:3
目的 探讨碱性成纤维细胞生长因子(bFGF)、表皮生长因子(EGF)在体外条件下对骨髓基质干细胞(BMSCs)向神经千细胞(NSCs)和神经样细胞分化的诱导作用。方法 采用出生4周左右大鼠的全骨髓细胞进行培养,传至第3代时,分为两组:实验组细胞加入bFGF和EGF,进行诱导分化;对照组不加因子继续培养。在倒置显微镜下每日观察,记录BMSCs的诱导分化情况,并应用免疫组化技术对细胞进行兔抗巢蛋白(Nestin)单抗、兔抗神经元特异性烯醇化酶(NSE)单抗、兔抗胶质纤维酸性蛋白(GFAP)单抗鉴定。结果 实验组诱导7d后有部分细胞具备神经元样细胞形态,胞体锥形或圆形,有较长单极或多极的突起,均有Nestin、NSE、GFAP阳性细胞表达,且3种细胞数量差别有显著性(t=3.266~6.099,P〈0.05)。而对照组细胞仍为典型的成纤维细胞形态,无Nestin、NSE、GFAP阳性细胞。结论 bFGF、EGF可以诱导BMSCs向NSCs分化,并可调控神经元分化,促进神经元细胞成熟。 相似文献
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BackgroundHepatic alveolar echinococcosis (HAE) is considered to be one of the most deadly chronic parasitic diseases in the world. We have shown that the incidence of cholangitis in patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) was increased significantly. On this finding, we carried out, a preliminary study on the risk factors for cholangitis after ERCP.AimsTo retrospectively detect the risk factors for post-ERCP cholangitis in patients with biliary tract affected by HAE.MethodsThe study included data from 51 cases of AE who had undergone therapeutic ERCP between January 2015 and December 2019. Demographic and treatment data were extracted from the medical records, and the association between potential risk factors and the development of post-ERCP cholangitis was evaluated using a collected database.ResultsThere were five cases of mild cholangitis after ERCP (Tokyo criteria), and no moderate or severe cholangitis occurred. The incidence rate of cholangitis after ERCP was 9.8%. Univariate analysis showed hilar bile duct stenosis (p = .016), endoscopic retrograde biliary drainage (p = .007), a stent diameter ≥8.5 Fr (p = .000) and single stent implantation (p = .010) were risk factors for post -ERCP cholangitis. All cases of cholangitis improved under conservative treatment.ConclusionPatients with hilar bile duct compression or endoscopic retrograde biliary drainage appeared to be more likely to develop post-ERCP cholangitis. The number and diameter of biliary stents may influence post-ERCP cholangitis. Sample size and clinical heterogeneity are two insurmountable difficulties, and a larger sample size needs to be collected to verify the risk factors for screening.
KEY MESSAGES
- Many studies reported the post-ERCP complications in patients with hepatic alveolar echinococcosis and found that the incidence of post-ERCP cholangitis was significantly high. Therefore, we conducted a preliminary study on the risk factors of postoperative cholangitis in patients who underwent ERCP.
- The incidence rate of cholangitis after ERCP was 9.8%. We found that hilar bile duct stenosis, and endoscopic retrograde biliary drainage, were risk factors for cholangitis, and stent diameter and the number of stent implantation may influence the incidence rate of cholangitis after ERCP.
- Sample size and clinical heterogeneity are two insurmountable difficulties, and a larger sample size needs to be collected to verify the risk factors of screening.