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101.
Plesch W Wolf T Breitenbeck N Dikkeschei LD Cervero A Perez PL van den Besselaar AM 《Thrombosis research》2008,123(2):381-389
Background
This is the first paper reporting a performance verification study of a point-of-care (POC) monitor for prothrombin time (PT) testing according to the requirements given in chapter 8 of the International Organization for Standardization (ISO) 17593:2007 standard “Clinical laboratory testing and in vitro medical devices — Requirements for in vitro monitoring systems for self-testing of oral anticoagulant therapy”. The monitor under investigation was the new CoaguChek XS system which is designed for use in patient self testing. Its detection principle is based on the amperometric measurement of the thrombin activity generated by starting the coagulation cascade using a recombinant human thromboplastin.Methods
The system performance verification study was performed at four study centers using venous and capillary blood samples on two test strip lots. Laboratory testing was performed from corresponding frozen plasma samples with six commercial thromboplastins. Samples from 73 normal donors and 297 patients on oral anticoagulation therapy were collected. Results were assessed using a refined data set of 260 subjects according to the ISO 17593:2007 standard.Results
Each of the two test strip lots met the acceptance criteria of ISO 17593:2007 versus all thromboplastins (bias − 0.19 to 0.18 INR; > 97% of data within accuracy limits). The coefficient of variation for imprecision of the PT determinations in INR ranged from 2.0% to 3.2% in venous, and from 2.9% to 4.0% in capillary blood testing. Capillary versus venous INR data showed agreement of results with regression lines equal to the line of identity.Conclusion
The new system demonstrated a high level of trueness and accuracy, and low imprecision in INR testing. It can be concluded that the CoaguChek XS system complies with the requirements in chapter 8 of the ISO standard 17593:2007. 相似文献102.
官萃 《中国医疗器械信息》2013,(8):14-19,30
随着轴承技术的进步,人们对轴承应用和轴承本身的要求越来越严格,比如越来越高的节能和清洁度要求。本文将论述轴承清洁度问题,根据ISO 281:2007,清洁度是影响轴承寿命的一项关键因素,提高清洁度可以延长轴承的使用寿命,尤其是在真空泵、压缩机、医疗设备等高科技应用领域。 相似文献
103.
ISO 9000管理方法在发热门诊护理管理中的应用 总被引:1,自引:0,他引:1
探讨ISO9000质量标准在发热门诊运行中对规章制度的建立、严重急性呼吸综合征(SARS)的诊治流程和为发热患者提供高质量护理服务中的应用价值。在发热门诊依据ISO9000标准来实现管理职责的文件化、护理服务项目的流程化、消毒隔离防护的标准化、人力配置的合理化和护理标识的可追溯性的管理。通过ISO9000标准在发热门诊的实际应用,有效地控制传染源,使发热患者和SARS患者得到良好的诊疗服务。 相似文献
104.
《Mayo Clinic proceedings. Mayo Clinic》2022,97(8):1437-1448
ObjectiveTo compare dietary factors between incident symptomatic stone formers and controls, and among the incident stone formers, to determine whether dietary factors were predictive of symptomatic recurrence.Patients and MethodsWe prospectively recruited 411 local incident symptomatic kidney stone formers (medical record validated) and 384 controls who were seen at Mayo Clinic in Minnesota or Florida between January 1, 2009, and August 31, 2018. Dietary factors were based on a Viocare, Inc, food frequency questionnaire administered during a baseline in-person study visit. Logistic regression compared dietary risk factors between incident symptomatic stone formers and controls. Incident stone formers were followed up for validated symptomatic recurrence in the medical record. Cox proportional hazards models estimated risk of symptomatic recurrence with dietary factors. Analyses adjusted for fluid intake, energy intake, and nondietary risk factors.ResultsIn fully adjusted analyses, lower dietary calcium, potassium, caffeine, phytate, and fluid intake were all associated with a higher odds of an incident symptomatic kidney stone. Among incident stone formers, 73 experienced symptomatic recurrence during a median 4.1 years of follow-up. Adjusting for body mass index, fluid intake, and energy intake, lower dietary calcium and lower potassium intake were predictive of symptomatic kidney stone recurrence. With further adjustment for nondietary risk factors, lower dietary calcium intake remained a predictor of recurrence, but lower potassium intake only remained a predictor of recurrence among those not taking thiazide diuretics or calcium supplements.ConclusionEnriching diets in stone formers with foods high in calcium and potassium may help prevent recurrent symptomatic kidney stones. 相似文献
105.
引入ISO9001:2000系列标准,结合全科医学、护理学、中毒、公共卫生事件应急预案等,制定科学化、规范化、操作性强的标准及流程,提高护理人员对突发事件的处理能力,为抢救病人赢得了时间。 相似文献
106.
107.
The importance of EN ISO 15189 accreditation of allergen‐specific IgE determination for reliable in vitro allergy diagnosis 下载免费PDF全文
C. Lambert A. Sarrat F. Bienvenu S. Brabant P. Nicaise‐Roland M.‐A. Alyanakian P.‐A. Apoil C. Capron R. Couderc B. Evrard D. Jaby C. Hémont C. Lainé M. Lelong D. Mariotte J. Martinet G. Rénier J. Sainte‐Laudy T. Tabary E. Treiner B. Uring‐Lambert C. Vigneron M. Vivinus F. Witthuhn J. Vitte 《Allergy》2015,70(2):180-186
108.
按照质量管理八项原则,贯彻IS09001标准,有利于全面规范研究所管理,提高科研声誉;有利于取得顾客的信任;有利于优化研发过程,提高科研成果品质;该体系结构严谨、内容丰富、规定具体、操作性和通用性强.通过标准建设,可进一步促进研究所的科技成果转化为生产力. 相似文献
109.
Andreas Pfützner David C. Klonoff Scott Pardo Joan L. Parkes 《Journal of diabetes science and technology》2013,7(5):1275-1281
Background
The Parkes error grid, which was developed in 1994, presented performance zones for blood glucose (BG) monitors with borders that were not mathematically specified at the time the grid was published.Methods
In this article, we (1) review the history of the Parkes error grid, (2) present the never-before-published exact coordinates and specifications of the grid so that others may produce an exact replica of the original grid, and (3) discuss our suggestions how this metric should be applied.Results
The new ISO15197:2013 guideline for system accuracy assessment of BG meters for patient self-measurement incorporates use of this metric for defining acceptable accuracy of BG monitors. It is expected that, for regulatory purposes, this document will stipulate that the error grid version for type 1 diabetes should be applied with the caveat that only the A zone represents acceptable accuracy.Conclusions
It remains to be seen by how much the new error grid, which is currently being developed by the Food and Drug Administration/Diabetes Technology Society/American Diabetes Association/The Endocrine Society/ Association for Advancement of Medical Instrumentation, will deviate from the Parkers error grid. 相似文献110.
本文对ISO9000质量管理体系在军队医疗机构应用的可行性进行了探讨,重点为军队医院开展ISO9000质量管理体系的问题,并对ISO9000质量管理体系在医院的运行情况作了系统的分析和评价。从ISO9000质量管理体系在本单位运行的初步情况看,军队医疗机构推行ISO9000质量管理体系是可行的。 相似文献