八段锦联合复方降脂茶对非酒精性脂肪性肝病患者肝脏脂肪含量、血脂的影响

目的:探讨八段锦联合复方降脂茶对非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)患者肝脏脂肪含量,血三酰甘油、低密度脂蛋白、高密度脂蛋白水平的影响。方法:120例NAFLD患者随机分为对照组和观察组各60例。对照组给予常规饮食和运动指导,观察组在对照组干预基础上给予八段锦运动及复方降脂茶。3个月后,比较两组患者肝脏脂肪含量,血三酰甘油、低密度脂蛋白、高密度脂蛋白水平。结果:干预后,观察组患者脂肪含量为(241.65±14.65)dB·mW^-1,对照组患者脂肪含量为(259.60±15.91)dB·mW^-1,两组患者肝脏脂肪含量比较,差异有统计学意义(P<0.05)。干预后,观察组患者三酰甘油为(2.45±1.04)mmol·L^-1,对照组患者三酰甘油为(2.98±1.06)mmol·L^-1,两组比较,差异有统计学意义(P<0.05);观察组患者低密度脂蛋白为(3.59±0.59)mmol·L^-1,对照组为(4.0...     

Mycotoxins in Tea ((Camellia sinensis (L.) Kuntze)): Contamination and Dietary Exposure Profiling in the Chinese Population

Tea is popular worldwide with multiple health benefits. It may be contaminated by the accidental introduction of toxigenic fungi during production and storage. The present study focuses on potential mycotoxin contamination in tea and the probable dietary exposure assessments associated with consumption. The contamination levels for 16 mycotoxins in 352 Chinese tea samples were determined by ultra-performance liquid chromatography–tandem mass spectrometry. Average concentrations of almost all mycotoxins in tea samples were below the established regulations, except for ochratoxin A in the dark tea samples. A risk assessment was performed for the worst-case scenarios by point evaluation and Monte Carlo assessment model using the obtained mycotoxin levels and the available green, oolong, black, and dark tea consumption data from cities in China. Additionally, we discuss dietary risk through tea consumption as beverages and dietary supplements. In conclusion, there is no dietary risk of exposure to mycotoxins through tea consumption in the Chinese population.     

饮红茶对大鼠慢性缺氧性肺动脉高压的影响

慢性缺氧过程中，饮红茶的大鼠（HT组）平均肺动脉压（Ppa）为2.50±0.20kPa，肺血管阻力（PVR）为2824.80±658.69kPa·s~(-1)／L，均显著低于缺氧对照组（Ppa为2.97±0.25kPa，PVR为3763.46±529.62kPa·s~(-1)／L），而HT组肺血管对急性缺氧的反应性（22.50±6.16％）则显著强于缺氧对照组（10.65±3.80％）。结果表明，长期饮红茶可防止大鼠慢性缺氧性肺动脉高压的形成。     

普洱熟茶片调节血糖的临床观察

目的：观察普洱熟茶标准提取物普洱熟茶片对空腹血糖的影响。方法：将30例糖尿病患者按照空腹血糖水平分为4组,服用普洱熟茶有效成分提取物普洱熟茶片。结果：空腹血糖损伤组与2型糖尿病3组服用普洱熟茶片前后相比,P〈0．05,2型糖尿病1组及2型糖尿病2组服用普洱熟茶片前后相比较,P〈0．05。2型糖尿病3组与空腹血糖损伤组、2型糖尿病1组、2型糖尿病2组相比较,P〈0．05。结论：普洱熟茶标准提取物普洱熟茶片能够降低糖尿病患者空腹血糖水平,尤其对空腹血糖损伤患者及空腹血糖≥11．1mmol／L患者具有明显的降血糖作用。     

茶渣中蛋白质酶法提取工艺

研究了蛋白酶法提取茶叶加工后茶渣中蛋白质的工艺。结果显示，碱性蛋白酶和复合蛋白酶提取效果较好；碱性蛋白酶法提取的最佳工艺为酶加量49／6、液固比35：1（mL／g）、提取时间4h，提取率可达34．29，6；复合蛋白酶法提取的最佳提取工艺为酶加量39，6、液固比35：1（mL／g）、提取时间4h，提取率可达18．69／6；双酶法提取中，采用先复合蛋白酶，后碱性蛋白酶，提取效果较好，并且碱性蛋白酶占总酶加量比例对提取率的影响较大，当碱性蛋白酶占25％时，提取率达到最大，为42．19，6；双酶法提取的最佳提取工艺为pH8．0，温度60℃，酶加量49，6，提取率可达47．8％。     

南岳毛尖抑制小鼠移植性S_(180)生长作用的初步研究

本研究用南岳毛尖(一级绿茶)浸泡液灌胃处理皮下移植S_(180)的Babl/c小白鼠,观察其抑瘤效果。结果表明该绿茶可明显抑制肿瘤的生长,瘤重明显轻于对照组(P<0.05);空泡变性瘤细胞数、瘤块内坏死灶数明显多于对照组(P<0.001);瘤细胞核分裂数明显少于对照组(P<0.005),对瘤细胞有较好的杀灭作用。该研究证明南岳毛尖是一种天然防癌抗癌物质,对干预肿瘤的发生和发展有重要意义。     

山楂叶茶水提物抗氧自由基作用的研究

用外源性氧自由基，测定山楂叶茶水提物对红细胞膜的保护作用和对羟自由基的抑制和清除作用。实验证明：山楂叶茶水提物对氧自由基发生体系产生的脂质过氧化作用有明显的抑制效应，能减少对Ｏ２红细胞膜流动性的破坏，同时对Ｆｅｎｔｏｎ反应生成的·ＯＨ也具有较强的抑制和清除作用，且强于·ＯＨ特异性清除剂甘露醇。     

Tea drinking and risk of pancreatic cancer

Background Epidemiologic studies have reported inconsistent results regarding tea consumption and the risk of pancreatic cancer. This study aimed to investigate whether tea consumption is related to the risk of pancreatic cancer. Methods We searched Medline, EMBASE, ISI Web of Science, and the Cochrane library for studies published up to November 2013. We used a meta-analytic approach to estimate overall odds ratio （OR） and 95% confidence interval （CO for the highest versus the lowest tea consumption categodes. Results The summary OR for high versus no/almost never tea drinkers was 1.04 （95% CI： 0.91-1.20）, with no significant heterogeneity across studies （P=0.751;/2=0.0%）. The OR was 0.99 （95% CI： 0.77-1.28） in males and 1.01 （95% CI： 0.79- 1.29） in females. The OR was 1.07 （95% CI： 0.85-1.34） in Asian studies, 1.05 （95% CI： 0.84-1.31） in European studies, and 0.98 （95% CI： 0.72-1.34） in the US studies. The OR was 0.87 （95% CI： 0.69-1.10） without adjustment for a history of diabetes and 1.16 （95% CI： 0.97-0.39） after adjustment for a history of diabetes. The OR was 0.90 （95% CI： 0.72-1.12） without adjustment for alcohol drinking and 1.16 （95% CI： 0.96-1.39） after adjustment for alcohol drinking. The OR was 0.97 （95% CI： 0.76-1.25） without adjustment for BMI and 1.07 （95% CI： 0.87-1.31） after adjustment for BMI. Conclusion This systematic meta-analysis of cohort studies dose not provide quantitative evidence that tea consumption is appreciably related to the risk of pancreatic cancer, even at high doses.     

茶多酚改善大鼠缺血/再灌注心脏功能和能量代谢并抑制体外培养心肌细胞的钙内流

目的：探讨茶多酚对缺血/再灌注心脏损伤的保护作用,并研究心脏能量代谢和心肌细胞钙内流是否参与了心脏缺血/再灌注损伤的保护作用。方法在大鼠Langendorff离体心脏上实施缺血/再灌注各30 min,用一导管经压力换能器连接放大器记录心功能指标;用31P NMR技术测定心脏的能量代谢,全细胞膜片钳技术记录心肌细胞钙内流。结果与对照组比较,茶多酚（2.5 mg/L）能使缺血/再灌注心脏的心室发展压、左心室压最大收缩速率（+dp/dtmax）、左心室压最大舒张速率（-dp/dtmax）和冠脉流量显著增加（P<0.05）,并显著改善缺血/再灌注心脏的能量代谢,增加心肌ATP和PCr含量（P<0.05）。浓度为2.5和5.0 mg/L的茶多酚均能显著抑制培养心肌细胞的钙内流（P<0.01）。结论茶多酚对大鼠离体心脏缺血/再灌注损伤的保护作用可能与其改善心肌能量代谢、抑制心肌细胞钙内流的作用有关。     

Potentiating effects of honey on antioxidant properties of lemon-flavoured black tea

Health benefits including antioxidant potential of black tea (Camellia sinensis), lemon (Citrus limon) and honey bees (Apis mellifera) have been extensively reported. Nevertheless, nothing is reported about the effects of their concomitant use. Herein, those effects were evaluated in infusions of lemon-flavoured black tea with three different kinds of honey (light amber, amber and dark amber) from Lavandula stoechas, Erica sp. pl. and other indigenous floral species from north-east Portugal, a region with high amounts of this food product. Data obtained showed that the use of honey (dark amber>amber>light amber) potentiates the antioxidant activity of lemon-flavoured black tea, increasing the reducing power and lipid peroxidation inhibition properties, as also the antioxidant contents such as phenolics, flavonoids and organic acids including ascorbic acid.