谷朊粉废水提取物在肉制品中的应用

介绍了一种从谷朊粉废水中提取戊聚糖的工艺,由此工艺得到的产品(戊聚糖质量分数约70%,蛋白质质量分数约20%)能较好地保持戊聚糖的特性.研究了其它添加剂(卡拉胶)对戊聚糖的乳化性,戊聚糖对肉制品持油、持水性以及其质构的影响.谷朊粉废弃水提取物与卡拉胶的复配产品在添加量(质量分数)为6%时能使肉制品有较好的持油性和相应的质构.     

明党参根中维生素及其水煎膏中无机元素的分析

目的:考察明党参根中营养元素的种类及含量,探讨其补益功效的物质基础.方法:采用高效液相色谱法、荧光分光光度法及扫描电子微量分析法,测定明党参根中维生素的含量和水煎膏中无机元素的含量.结果:明党参根含脂溶性维生素E、K分别为259.2、64.1μg/kg,水溶性维生素C、B1、B2分别为78.5、0.6、0.7 mg/kg.明党参水煎膏中含丰富的钾和钙离子.结论:明党参富含人体必需的有益元素,作为食用中药是有其物质基础的.     

夜来香根茎水提取液局部麻醉作用的研究

目的：研究夜来香(CN)根茎水提取液的局部麻醉作用及其作用机制。方法：采用蟾蜍离体坐骨神经动作电位法、豚鼠皮丘法、椎管麻醉法、表面麻醉法。结果：20％的CN水提取液对蟾蜍离体坐骨神经动作电位可完全消失，但较1％的普鲁卡因稍弱。豚鼠皮丘实验表明，20％CN提取液有浸润麻醉作用，其浸润麻醉效果与1％的普鲁卡因相似，而且盐酸肾上腺素可增强其麻醉强度和明显延长局麻作用时间；家兔椎管麻醉实验表明CN提取液有明显的椎管麻醉作用；CN提取液对家兔角膜也有一定的表麻作用，只是作用强度及持续时间比1％的普鲁卡因稍弱或稍短。结论：CN提取液有明显的局部麻醉作用。     

微乳对难溶性药物增溶机理的研究

目的:初步探讨微乳对难溶性药物的增溶机理.方法:经处方筛选及相图研究确定(BL-9/正丁醇3∶1)/油/水比例为9∶1∶40的微乳处方;以二氢吡啶类药物为模型药物,测定其在微乳、胶束和油相中的溶解度及油/水分配系数;根据化学结构,采用计算机软件计算药物的特性参数,并结合模型药物的特性分析微乳增溶难溶性药物的机理.结果:微乳对药物的增溶效果远大于油相和胶束,并随药物的脂溶性和空间结构的改变而变化.结论:微乳可用于增溶难溶性药物,且脂溶性越大,空间位阻越小,增溶效果越明显.     

高原低氧对大鼠学习记忆影响的实验研究

目的：研究高原低氧环境对大鼠学习记忆的影响。方法：利用新生大鼠低氧模型和胎鼠低氧模型，采用爬杆实验和Morris水迷宫实验进行检测.结果：爬杆实验中习得的速度减慢，消退速度加快。Morris水迷宫实验中逃避潜伏期延长，撤除平台后跨越平台次数减少。结论：高原低氧环境下大鼠的学习记忆能力受到抑制，可能与长期低氧后海马NMDA受体数量和功能的下降有关。     

Gastric contents and pH after oral premedication

Forty women, aged 26-40 years, were investigated with regard to gastric contents and pH before general anaesthesia. The patients were divided into two groups (20 in each). Group 100 received 0.3 mg kg-1 diazepam orally with 100 ml of water 2 h before surgery. Group 50 received 0.3 mg kg-1 diazepam with 50 ml of water 2 h before surgery. The amount of gastric content was significantly greater in Group 100 than in Group 50 (P less than 0.05). There was no statistical difference in pH values between the groups. The number of patients with both gastric pH less than 2.5 and gastric volume greater than 25 ml was significantly higher in Group 100 compared to Group 50 (P less than 0.05). We cannot recommend the use of oral premedication using these amounts of water, considering the increased risk of aspiration of gastric contents.     

Assessment of anti-inflammatory activity of Poria cocos in sodium lauryl sulphate-induced irritant contact dermatitis

OBJECTIVE: In the present study, we evaluated the anti-inflammatory activity of Poria cocos (PoCo) on experimentally induced irritant contact dermatitis (ICD) in a repeated sodium lauryl sulphate (SLS) irritation model. METHODS: The anti-irritative effect of PoCo was evaluated with a visual score and quantified by non-invasive bioengineering methods, namely chromametry and transepidermal water loss. Three concentrations of PoCo in base cream DAC (amphiphilic emollient; German pharmacopoeia) were tested in a 4-day repetitive irritation test using SLS. RESULTS: A statistically significant anti-inflammatory activity was observed for PoCo by all three methods when applied in parallel to the induction period of ICD. Application of PoCo after induction of ICD once a day for 5 days, starting just at the end of 4 days, was without any effect. CONCLUSION: An anti-inflammatory efficacy of PoCo on the elicitation phase of the ICD induced by repeated SLS test could be observed and quantified by three independent, non-invasive biophysical assessment parameters. This effect can be explained by its influence on pro-inflammatory enzymes, namely phospholipase A2.     

Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: A study using oxygen 15-labeled water PET

BACKGROUND: Myocardial perfusion single photon emission computed tomography (SPECT) occasionally fails to detect coronary stenosis in patients with coronary artery disease (CAD). We evaluated coronary flow reserve (CFR) using oxygen 15-labeled water in areas with and without ischemia on technetium 99m tetrofosmin stress perfusion SPECT in patients with angiographically documented CAD. METHODS AND RESULTS: Twenty-seven patients with CAD and eleven age-matched normal subjects were studied. Baseline myocardial blood flow (MBF) and MBF during hyperemia induced by intravenous adenosine triphosphate infusion (0.16 mg. kg(-1). min(-1)) were determined with the use of O-15-labeled water positron emission tomography, and the CFR was calculated. Tc-99m tetrofosmin stress/rest SPECT was performed for comparison. On the basis of the results of coronary angiography and SPECT, coronary segments were divided into 3 types: segments with coronary stenosis and a perfusion abnormality on stress SPECT imaging (group A, n = 16), segments with coronary stenosis without a perfusion abnormality (group B, n = 42), and remote segments with no coronary stenosis or perfusion abnormality (group C, n = 18). Baseline MBF values were similar among the 3 groups. CFR in group A was lower (1.82 +/- 0.54) than in group B (2.22 +/- 0.87, P <.05), in group C (2.92 +/- 1.21, P <.01), and in normal segments (3.86 +/- 1.24, P <.001). CFR in group B was lower than in group C (P <.02) and in normal segments (P <.001). CFR in group C was lower than in normal segments (P <.02). CONCLUSIONS: Areas with a perfusion abnormality on stress SPECT had reduced CFR. In the areas without a perfusion abnormality and with coronary stenosis, lowering of CFR was intermediate between the areas with a perfusion abnormality and remote segments. Moreover, CFR was slightly, but significantly, lower in remote segments in patients with CAD compared with normal segments.     

低张结肠水灌肠CT检查诊断结肠癌的价值

目的 :探讨低张结肠水灌肠CT检查对结肠癌的CT表现及诊断价值。材料和方法 :肌注 65 4 2 2 0mg后 ,结肠灌注微温生理盐水进行CT扫描。分析经手术病理证实的 3 8例结肠癌资料。结果 :CT显示肿瘤部位准确率为 10 0 % ,CT分期与手术分期符合率为 92 % ,低张结肠水灌肠CT可见病变肠壁增厚、突出腔内的肿块、肠腔狭窄及其浆膜面毛糙 ;可见结肠癌侵犯邻近器官、淋巴结肿大及远处转移。结论 :低张结肠水灌肠CT检查对结肠癌的术前诊断有很大的价值。