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71.
本文报告了10例慢性泪囊炎患者,行泪囊鼻腔吻合术后,发生吻合口阻塞,再次行泪囊鼻腔吻合术,手术治愈率100%。并就其阻塞的原因、防止方法、治疗方法进行了讨论 相似文献
72.
对29例慢性乙型肝炎伴肝胆结石患者.采用Elisa和斑点杂交技术检测外周静脉血、胆管胆汁和门静脉血中乙型肝炎两对半及HBV-DNA.并比较HkAg含量.结果,外周静脉血、胆汁和门静脉血中HBsAg浓度分别为;2244.73±59722ng/ml、1181.65±370.91ng/ml、2013.62±483.47ng/ml;HBV-DNA阳性检出率分别为62.07%(18例),72.41%(21例)及68.97%(20例).提示肝细胞内复制的HHV在进入血循环的同时,部分随胆汁的分泌排入肠道,并可能通过受损肠粘膜进入门静脉再回到肝脏,造成HBV对肝脏的重复感染。 相似文献
73.
含化复方新诺明引起过敏性休克一例患者,女,30岁,因咽峡炎于1992年8月7日晚10时自行含化复方新诺明(广州白云山制药厂)两片、约7分钟后,出现全身搔痒,当即肌注苯海拉明20mg,静推10%葡萄糖酸钙10ml,旋即全身泛起荨麻疹,奇痒难忍,眼睑轻度水肿,嘴唇发麻,咽部“发紧”,发音困难,烦躁,立即给予吸氧,静推地塞米松10mg,皮下注射肾上腺素0.5mg,与此同时,患者脸色苍白、鼻尖、未梢发凉,口唇紫绀,时吸暂停,意识丧失,脉搏140次/分,细数,血压测不到,再次给予皮下注射肾上腺素0.5mg,静点地塞米松15mg,并给予扩容、纠酸,约一分钟后,欲行气管切开时,患者呼吸渐恢复、继而意识清楚,紫绀减轻,血压10/16kPa,遂休克纠正。复方新诺明片致过敏性休克者尚属少见,该患者有青霉素过敏史,局部用药又易致过敏,考虑喉头痉挛与药物含化有关。(长治市人民医院王爱军,崔文华,郭天然)含化复方新诺明引起过敏性休克一例@王爱军,崔文华,郭天然$长治市人民医院 相似文献
74.
G. Lallement Didier Clarençon Catherine Masqueliez Dominique Baubichon Monique Galonnier Marie-France Burckhart Michel Peoc’h Jean Claude Mestries 《Archives of toxicology》1997,72(2):84-92
Organophosphorus nerve agents are still in use today in warfare and as terrorism compounds. Classical emergency treatment
of organophosphate poisoning includes the combined administration of a cholinesterase reactivator (an oxime), a muscarinic
cholinergic receptor antagonist (atropine) and a benzodiazepine anticonvulsant (diazepam). However, recent experiments with
primates have demonstrated that such treatment, even when administered immediately after organophosphate exposure, does not
rapidly restore normal electroencephalographic (EEG) activity and fails to totally prevent neuronal brain damage. The objective
of this study was to evaluate, in a realistic setting, the therapeutic benefit of administration of GK-11 (gacyclidine), an
antiglutamatergic compound, as a complement to the available emergency therapy against organophosphate poisoning. GK-11 was
injected at a dose of 0.1 mg/kg (i.v) after a 45-min latency period to heavily intoxicated (8 LD50) primates. Just after intoxication, man-equivalent doses of one autoinjector containing atropine/pralidoxime/diazepam were
administered. The effects of GK-11 were examined on survival, EEG activity, signs of toxicity, recovery after challenge and
central nervous system histology. The present data demonstrate that treatment with GK-11 prevents the mortality observed after
early administration of classical emergency medication alone. EEG recordings and clinical observations also revealed that
GK-11 prevented soman-induced seizures and motor convulsions. EEG analysis within the classical frequency bands (beta, theta,
alpha, delta) demonstrated that central activity was totally restored to normal after GK-11 treatment, but remained profoundly
altered in animals receiving atropine/pralidoxime/diazepam alone. GK-11 also markedly accelerated clinical recovery of soman-challenged
primates. Lastly, this drug totally prevented the neuropathology observed 3 weeks after soman exposure in animals treated
with classical emergency treatment alone. GK-11 represents a promising adjuvant therapy to the currently available emergency
polymedication to ensure optimal management of organophosphate poisoning in man. This drug is presently being evaluated in
a human clinical trial for a different neuroprotective indication.
Received: 16 June 1997 / Accepted: 23 September 1997 相似文献
75.
铅性肾病的流行病学分析 总被引:20,自引:11,他引:9
我们检查了铅接触人员1023名,发现铅性肾病84例,患病率8.2%。女性34例(7.2%),男性50例(9%),男女铅性肾病患病率无显著性差异。印刷厂空气铅浓度平均0.0069mg/m3,蓄电池厂为0.1005mg/m3,铅矿为0.5mg/m3。铅性肾病患病率分别为4.73%,8.3%和28.57%(P<0.005)。分析铅性肾病患病率与年龄和铅接触年限的关系。年龄小于30岁,~40岁,~50岁和大于50岁者,铅性肾病患病率分别为5.5%,8.6%,12.1%,和15.6%(P<0.05)。铅接触年限小于10年,~20年和大于20年者,铅性肾病患病率分别为6.6%,9.9%和13.1%(P<0.05)。 相似文献
76.
苯作业工人白细胞降低者的总估校正现患率 总被引:7,自引:0,他引:7
选择乡镇工业苯作业工人4次外周血白细胞计数中的间隔半年的两次数据,应用俘获再俘获法,计算其白细胞降低者的总估校正现患率(ACPR)。结果苯接触组为36.8l%(29.14%~44.48%),对照组为12.71%(7.20%~18.22%)具有显著差异,其相对危险度为2,9。用常规法求得的4次检出率分别是:苯接触组为26.37%,18.73%,27.93%,36.76%;对照组为6。85%,7.38%,7.94%,15.00%。均在其ACPR之95%可信限内,可见ACPR计算方法简便、结果准确,值得推广。对于稳定的人群,可用其每年一次的健康监护资料计算ACPR。 相似文献
77.
1976~1991年我院收治慢性重症病毒性肝炎并发曲霉菌感染15例,感染于住院后3~112天,<30天9例。以血性痰液、胸水、腹水、脑脊液为特点。多数周围血象白细胞不增高,中性粒细胞增高,IgG增高,曲霉菌( );感染后2~10天均死亡。感染前咽部检出白色念珠菌6例,滥用抗生素者占80%。 相似文献
78.
Twenty-four chronic schizophrenic long-stay hospital patients were identified, who had not received neuroleptic drugs for 8–30 (average 8 months) and met or exceeded a minimum criterion of severity of negative symptoms. They were rendomly alocated to either sulpiride 200 mg twice daily or matching placebo, on a double-blind basis for 12 weeks. The results showed that low-dose sulpiride was significantly better than placebo in relation to improvements in negative symptoms. The changes in social behaviour were complex and not obviously related to symptom improvement; exhibited abnormal behaviour, a major factor in preventing successful return to the community, consistently improved only on the active drug. 相似文献
79.
Paul Saenger Kenneth M. Attie Joan DiMartino-Nardi Richard N. Fine 《Pediatric nephrology (Berlin, Germany)》1996,10(3):261-263
Carbohydrate metabolism was evaluated by fasting and postprandial glucose, insulin, and hemoglobin (Hb)A1c levels in children with chronic renal insufficiency and various other growth disorders treated with growth hormone. Mean fasting and postprandial glucose remained unchanged throughout the 5-year study period in all four study groups. Median fasting insulin levels rose from lownormal levels into the normal range after 5 years of growth hormone. Average fasting insulin level after 5 years was 10 mU/l. Median postprandial insulin values also rose, yet remained within the normal range at the 5-year mark. Mean Hb A1c levels remained within low to middle end of the normal range in the patients with growth hormone deficiency, Turner syndrome, and idiopathic short stature. Mean Hb A1c levels at the 5 years were slightly elevated to 6.3% for the patients with chronic renal insufficiency. 相似文献
80.
生物反馈技术治疗慢性盆底疼痛综合征及慢性前列腺炎 总被引:13,自引:0,他引:13
目的:评估生物反馈刺激治疗对慢性盆底疼痛综合征(CPPS)及慢性前列腺炎(CP)的效果。方法:评估30例患者治疗前后,前列腺液(EPS)及精液(SF)和临床症状的变化,包括每日排尿次数、尿急、疼痛和生活质量。使用侵入型的生物反馈刺激治疗仪,治疗周期5~15d,每次20min。结果:30例患者中的14例进行了5次生物反馈治疗,10例进行了10次,6例进行了15次治疗(平均每位患者治疗8.6次),追踪生物反馈治疗后0~2个月,并比较治疗前和治疗后的结果,显示病情有明显好转。结论:生物反馈刺激治疗对CP或CPPS患者能明显改善疼痛、尿频、尿急和生活质量,对CP患者能减少EPS或SF中的WBC。 相似文献