双气囊小肠镜在儿科临床应用价值

目的评估双气囊小肠镜在儿科中的临床应用价值。方法回顾分析2016年7月—2019年4月行双气囊小肠镜检查的患儿临床资料。结果 44例患儿,男31例、女13例,平均年龄(9.64±3.36)岁(2岁9个月～15岁),平均体质量(34.91±15.10)kg(12.6～65 kg);不明原因消化道出血25例、腹痛16例、腹泻2例、P-J综合征1例。25例患儿检出病变,其中年龄6岁的7例患儿中4例检出病变。25例消化道出血患儿中16例检出病变,16例腹痛患儿中8例检出病变,2例腹泻患儿中1例检测病变。检出病变包括回肠憩室14例、克罗恩病4例、小肠非特异炎症(充血、糜烂、溃疡)3例。所有患儿在双气囊小肠镜检查后均未出现穿孔、严重出血及麻醉等并发症。结论双气囊小肠镜在儿童小肠疾病诊断中有重要作用,且安全。     

三步疗法治疗输卵管阻塞性不孕的研究

目的 探讨三步疗法治疗输卵管阻塞不孕的疗效.方法 将246例输卵管阻塞患者随机分为X光监视下Cook导丝介入及三步疗法疏通输卵管两组进行疗效对比分析.结果 两组复通率、受孕后异位妊娠发生率均有非常显著性差异.结论 三步疗法治疗输卵管阻塞优于X光监视下Cook导丝介入术.     

宫颈扩张双球囊导管和控释地诺前列酮栓促宫颈成熟的比较研究

目的:比较宫颈扩张双球囊导管和控释地诺前列酮栓用于妊娠晚期促宫颈成熟的有效性。方法:选取足月妊娠、具有引产指征、宫颈Bishop评分≤4分的62例初产妇,随机分成球囊组30例和药物组32例,比较两组的促宫颈成熟效果及24 h内阴道分娩率。结果:球囊组促宫颈成熟的显效率及有效率均显著高于药物组(93.3%vs 43.8%,P<0.01;100.0%vs78.1%,P<0.01);24 h内阴道分娩率球囊组显著高于药物组(53.3%vs 25.0%,P<0.05)。结论:对低评分宫颈不成熟的妊娠晚期患者,应用宫颈扩张双球囊促宫颈成熟的效果及24h内引产成功率均优于应用控释地诺前列酮栓。     

Diagnostics of inflammatory bowel disease

The diagnosis of inflammatory bowel disease (IBD) with its 2 main subforms, Crohn's disease and ulcerative colitis, is based on clinical, endoscopic, radiologic, and histologic criteria. This paradigm remains unchanged despite the advent of new molecular technologies for the examination of serum proteins and genetic sequences, respectively. The main innovations in diagnostic technologies include the development of more sophisticated endoscopic and noninvasive imaging techniques with the aim of improving the identification of complications, in particular malignant diseases associated with IBD. The future will see further progress in the identification of genetic susceptibility factors and of protein biomarkers and their use to describe the molecular epidemiology of IBD. It can be expected that future diagnostic algorithms will include molecular parameters to detect early disease or guide therapies by predicting the individual course of disease.