Effect of copper ionisation of the cervix on sperm migration

A method for deposition of elemental copper in the endocervix by ionisation has been developed with a view to achieve semipermanent contraception. In female rabbits incidence of conception decreased after ionisation of the cervix although high rate of contraception could not be achieved. A clinical trial on 24 volunteers has shown encouraging results. There was marked diminution in sperm count and depression of motility on post-coital test following copper ionisation of the endocervix. Microscopically, copper granules have been demonstrated in the endocervical epithelium, glands and stroma up to a period of six months. There is moderate lymphocytic infiltration.     

Clinical evaluation of new AMS GSC Plus Card

The AutoMicrobic System GSC Plus Card was compared to a broth microdilution reference method. Of 1660 minimum inhibitory concentration pairs, 86.1% were within 1 log₂ dilution range. A total of 89.2% of the GSC Plus results agreed qualitatively (susceptible, moderately susceptible, resistant). If chloramphenicol data are excluded, agreement is 88.8% and 89.9%, respectively. A total of only 0.90% results were very major or major discrepancies. This is significantly fewer major discrepancies than reported with other systems.     

Pregnancy-induced hypertension complicated by acute liver disease and disseminated intravascular coagulation. Five case reports.

Five cases of pregnancy-induced hypertension complicated by acute liver disease and DIC are presented. Initial misdiagnosis is described, with appropriate laboratory and histologic documentation of the true condition. Specific therapeutic recommendations are discussed and pathophysiologic mechanisms are suggested.