Pentacam眼前节分析仪检查参数对早期圆锥角膜的诊断价值

目的：分析Pentacam眼前节分析仪检查参数对早期圆锥角膜的诊断价值。

方法：回顾性对照研究,选取2019-01/2020-01于我院就诊的圆锥角膜患者100例124眼作为研究组,根据Amsler-Krumeich分级法将圆锥角膜患者按照严重程度分为轻度组(51眼)、中度组(43眼)和重度组(30眼),另外选取30名屈光度<-3.00D且无散光体检正常者右眼作为对照组,比较各组Pentacam眼前节分析仪参数\〖3mm直径范围水平中央曲率(K1)、3mm直径范围垂直中央曲率(K2)、角膜前表面最大屈光力(Kmax)、角膜散光(Cyl)、角膜最薄处的厚度(thinnest local)、角膜表面变异指数(ISV)、垂直不对称指数(IVA)、圆锥角膜指数(KI)、前房容积(ACV)以及前房深度(ACD)\〗情况,通过ROC曲线分析诊断早期圆锥角膜的敏感指标。

结果：研究组患者K1、K2、Kmax、Cyl、ISV、IVA、KI、ACD均明显高于对照组(P<0.05),thinnest local、ACV均明显低于对照组(P<0.05); 不同严重程度圆锥角膜患者的K1、K2、Kmax、Cyl、thinnest local、ISV、IVA、KI、ACV、ACD差异均有统计学意义(P<0.05),中度组和重度组K1、K2、Kmax、Cyl、ISV、IVA、KI、ACD均明显高于轻度组(P<0.05),thinnest local、ACV均明显低于轻度组(P<0.05),中度组和重度组K1、K2、Kmax、Cyl、thinnest local、ISV、IVA、KI、ACV、ACD比较有差异P<0.05); ROC诊断曲线结果显示,Kmax、thinnest local、ISV、IVA、KI是诊断圆锥角膜的敏感指标(AUC>0.85),其中ISV的诊断价值最高。

结论：Pentacam眼前节分析仪可有效测量圆锥角膜参数,不同严重程度圆锥角膜患者参数存在差异,其中Kmax、thinnest local、ISV、IVA、KI是诊断早期圆锥角膜的敏感指标,Pentacam眼前节分析仪检查参数对早期圆锥角膜具有较高的诊断价值。     

大黄提取液对脱矿釉质中钙溶出量的影响

目的 观察大黄提取液对脱矿釉质中钙溶出量的影响.方法 用不同浓度的大黄提取液和去离子水处理牙面后进行脱矿,ASCA生化分析仪对釉质脱矿后的脱矿液进行钙离子浓度的检测.结果 2 mg/ml和4 mg/ml大黄提取液处理后釉质钙溶出量<去离了水(P<0.01)、<1 mg/ml大黄提取液组(P<0.05),>2%氟化钠组但差异无统计学意义(P>0.05).1 mg/ml大黄提取液处理后釉质钙溶出量>2%氟化钠组(P<0.01),<去离子水组但差异无统计学意义(P>0.05).结论 2mg/ ml和4 mg/ml大黄提取液具有抑制脱矿釉质中钙溶出作用:2mg/ml大黄提取液为抑制钙溶出的起始有效浓度.     

二氢埃托啡自动静脉给药对大鼠免疫功能的影响

本研究采用计算机实时控制的定时自动静脉给药法，７２ｈ快速致使大鼠身体依赖性形成。各组戒断症状分值为：ＮＳ组１１．０±ｓ２．９；吗啡组８１．０±ｓ８．６；ＤＨＥ组４１．０±ｓ４．４，表明大鼠已形成明显身体依赖性（Ｐ＜０．００１）。在该模型基础上，利用３Ｈ－ＴｄＲ掺入法测得ＤＨＥ明显抑制大鼠淋巴细胞增殖反应。各组刺激指数为：８０．６９±ｓ１．７６；４９．０４±ｓ１．１０和３０．７７±ｓ２．１４（Ｐ＜０．００１）。利用ＭＴＴ法测ＤＨＥ也能抑制大鼠ＩＬ－２活性，各组Ａ５７０ｎｍ值为：０．３９±ｓ０．０３；０．３１±ｓ０．０４和０．２６±ｓ０．０４（Ｐ＜０．０１）。结果表明ＤＨＥ自动静脉给药明显抑制大鼠免疫功能，且较１０００倍剂量的吗啡作用更强     

Auditory and visual semantic priming using different stimulus onset asynchronies: An event-related brain potential study

Semantic priming effects (behavioral and electrophysiological) were compared in the visual and auditory modalities across three stimulus onset asynchronies (SOAs; 0, 200, and 800 ms). When both prime and target were presented in the visual modality (the prime just to the left of a fixation point and the target to the right) there were N400 priming effects present across the three SOAs. However, the N400 in the 0-ms SOA condition extended longer in time (800 vs. 500 ms) than in the other SOAs. When both the prime and target were presented in the auditory modality (the prime to the right ear and the target to the left), the largest priming effects were found for the 800-ms SOA. Moreover, there was a relatively early priming effect present in the 0- and 800-ms SOA conditions but not in the 200-ms condition. The results are discussed in terms of modality differences in the time course of word comprehension processes.     

Purification of antigenically intact Ro ribonucleoproteins; biochemical and immunological evidence that the 52-kD protein is not a Ro protein.

Anti-Ro sera immunoprecipitate Ro ribonucleoproteins (RNPs) from human cell extracts. Ro RNPs are biochemically heterogeneous particles whose functions are unknown and whose exact composition remains controversial. In addition to 60-kD Ro and to La proteins, a 52-kD polypeptide (p52) has been proposed to be a stable component of the Ro RNPs. To confirm the immunological studies supporting this hypothesis, we have biochemically purified Ro RNPs from HeLa cells using non-denaturing conditions. Ro RNPs segregated into three distinct populations, one of which only contained hY5 RNA (RohY5 RNPs). No p52 co-purified with Ro RNPs. Despite the absence of p52, purified Ro RNPs had biochemical and immunological properties identical to those of unfractionated Ro RNPs. Many anti-Ro sera only recognize p52 in immunoblots, and are said to be monospecific anti-p52. Preincubation with purified RohY5 RNPs (free of p52) of all human anti-Ro (including so-called monospecific anti-p52) sera abolished their capacity to immunoprecipitate Ro RNPs from unfractionated HeLa cell extracts. Conversely, preincubation of anti-Ro sera with purified p52 protein specifically inhibited recognition of p52 in immunoblots, but did not interfere with immunoprecipitation of Ro RNPs. Our data demonstrate that anti-p52 antibodies do not target intact Ro RNPs, nor do they target the native 60-kD Ro protein. Contrary to previous reports, p52 protein is not a stable component of antigenically intact Ro RNPs.     

芦荟凝胶用于治疗儿童口腔复发性溃疡的临床观察

目的:检验芦荟凝胶治疗儿童复发性口腔溃疡的疗效。方法:自行研制芦荟凝胶,以中药开喉剑喷雾剂作为对照,检验其治疗儿童复发性口腔溃疡的临床效果。结果:芦荟凝胶与开喉剑喷雾剂的效果相当,在缩小溃疡面积、改善充血情况、减轻疼痛、减少溃疡数目方面均没有显著差异。结论:芦荟凝胶对于儿童复发性口腔溃疡具有较好的临床治疗效果,是较理想的儿童口腔辅助药物。     

自操作式视力测定仪

本仪器在标准视力表面每一视标的下方安装发光二极管,通过发光管的发光来指定某一视标准提供受检者判别,采用数字电路实现受检者视标判别信息的鉴别,视标换行及同行视标的随机选取。受检者通过键盘输入自己对于视标开口方向的判别即可实现自操作式视力测定。所测定的视力由数码管显示。经试用,与人工视力检查对照其结果高度相关。     

野战X光片辅助洗片装置环境适应性实验研究

野战条件下,自动洗片机常因缺乏电源而无法正常工作。野战X光片辅助洗片装置的研制可很好解决在野外复杂地理、气候条件下的X光片洗片功能。该装置不仅可以较好的实现平时对于放射科工作人员的训练任务,使他们了解摄影后的X胶片进入洗片过程的每一个步骤要领,达到熟悉和适应野战条件下的对野战影像技师要求;同时该装置还可作为野战医院或卫生队平时的洗片之用。为验证该洗片装置在复杂地理、气候条件下能否正常工作,我们设计了一组模拟野战环境条件的洗片试验。结果洗出的胶片质量合格率为100%。     

TBA-40FR全自动生化分析仪加样系统感应报警故障检修

简要介绍了东芝TBA-40FR全自动生化分析仪加样系统感应报警故障判断与排除实践的要点。