乙型肝炎、丁型肝炎和戊型肝炎三重感染致重度黄疸患者1例

我们收治1例乙型肝炎、丁型肝炎和戊型肝炎三重感染致重度黄疸的患者，在护肝治疗的同时，应用氟美松、牛磺酸和苯巴比妥治疗，取得较好的退黄效果，现报道如下。     

从“凡温病者，始于上焦，在手太阴”论治早期乙肝

临床资料患者，女，17岁。因乏力、纳差、口苦、尿黄、腹泻3天入院。自诉入院前3天无明显诱因出现上述症状，自服感冒药后症状无减轻，2日前到上级医院检查肝功、二对半后诊断为“急性乙型肝炎”。患者转氨酶异常增高，故收入传染科住院，但因其输液反应大，无法耐受，遂入我院中医科求治。现症：发热，偶恶寒：乏力、纳差较前更甚：仍口苦、尿黄，未再腹泻；右胁部胀痛不适：面色略黄，色鲜明，     

肿瘤坏死因子—α抑制离体大鼠黄体细胞孕酮生成

用大鼠黄体细胞长期培养和放射免疫分析法观察肿瘤坏死因子－α（ＴＮＦ－α）对雌激素、孕激素分泌和ｃＡＭＰ生成的影响。结果表明，ＴＮＦ－α显著抑制基础孕酮分泌和ｃＡＭＰ生成，其抑制作用随作用时间的延长而增加。ＴＮＦ－α对雌二醇的生成无显著影响。＾３Ｈ－亮氨酸和＾３Ｈ胸腺密啶核苷掺入实验证实ＴＮＦ－α对黄体细胞孕酮生成的抑制作用并非毒性作用。     

胸椎黄韧带骨化症的手术治疗

<正> 胸椎黄韧带骨化可导致椎管狭窄、脊髓损害,严重可致截瘫,其病因尚不清楚。早期易误诊为血栓性脉管炎、神经炎、脑血管疾病等而延误治疗。我院1995～2001年收治胸椎黄韧带骨化症11例,均行手术切除减压,取得了良好的效果。总结报告如下。     

STUDY ON THE MECHANISM AND EFFECTS OF GLY-TYR-NH2 AND GLY-TYR-LYS ON RAT LUTEAL CELLS IN VITRO

The action of Gly-Tyr-NH2,(GY-NH2) and Gly-Tyr-LYS(GYK) on ^125I-LH binding,cAMP accumulation and progesterone production was investigated.Incubation of rat luteal cells for 2.5h with GH-NH2 and GYK at dosage of 0.2mmol/L caused a significant inhibition of basal and gonadotropin-stimulated steroidogenesis.GYNH2 and GYK were also foumnd to reduce cAMP formation in response to hCG.The activity of adenylate cyclase of luteal cells was inhibitd by 0.2mmol/LGY-NH2 and GYK.GY-NH2 and GYK at a concentration of 0.2mmol/L were not found to have an inhibitory effect on 8Br-cAMP-stimulated progesterone production.GY-NH2 and GYK did not affect ^125I-LH binding to LH receptors on the luteal cellsurface.These results suggest that GY-NH2 and GYK inhibit steroidogenesis at the step of gonadotropin-stimulated c AMP for mation in luteal cells.Adenylate cyclase in luteal cells was also inhibited.