全文获取类型
收费全文 | 27645篇 |
免费 | 1963篇 |
国内免费 | 667篇 |
专业分类
耳鼻咽喉 | 249篇 |
儿科学 | 1190篇 |
妇产科学 | 320篇 |
基础医学 | 2276篇 |
口腔科学 | 246篇 |
临床医学 | 3874篇 |
内科学 | 3517篇 |
皮肤病学 | 132篇 |
神经病学 | 1566篇 |
特种医学 | 981篇 |
外国民族医学 | 2篇 |
外科学 | 4767篇 |
综合类 | 3865篇 |
现状与发展 | 2篇 |
预防医学 | 2443篇 |
眼科学 | 119篇 |
药学 | 2685篇 |
35篇 | |
中国医学 | 888篇 |
肿瘤学 | 1118篇 |
出版年
2024年 | 85篇 |
2023年 | 434篇 |
2022年 | 823篇 |
2021年 | 1163篇 |
2020年 | 1117篇 |
2019年 | 1005篇 |
2018年 | 1022篇 |
2017年 | 962篇 |
2016年 | 985篇 |
2015年 | 976篇 |
2014年 | 1916篇 |
2013年 | 1988篇 |
2012年 | 1636篇 |
2011年 | 1685篇 |
2010年 | 1388篇 |
2009年 | 1319篇 |
2008年 | 1315篇 |
2007年 | 1314篇 |
2006年 | 1182篇 |
2005年 | 1026篇 |
2004年 | 882篇 |
2003年 | 718篇 |
2002年 | 632篇 |
2001年 | 569篇 |
2000年 | 444篇 |
1999年 | 407篇 |
1998年 | 367篇 |
1997年 | 307篇 |
1996年 | 266篇 |
1995年 | 237篇 |
1994年 | 199篇 |
1993年 | 188篇 |
1992年 | 196篇 |
1991年 | 152篇 |
1990年 | 142篇 |
1989年 | 132篇 |
1988年 | 120篇 |
1987年 | 100篇 |
1986年 | 117篇 |
1985年 | 135篇 |
1984年 | 103篇 |
1983年 | 82篇 |
1982年 | 107篇 |
1981年 | 80篇 |
1980年 | 58篇 |
1979年 | 38篇 |
1978年 | 40篇 |
1977年 | 28篇 |
1976年 | 24篇 |
1973年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Takayuki Murakami Atsushi Komiya Kunihisa Mikata Shigeki Kaneko Ichiro Ikeda 《International journal of urology》2007,14(3):240-241
Abstract: A 66-year-old man was referred to our hospital with chest discomfort and shortness of breath. Seven months previously he had undergone a laparoscopic left nephroureterectomy for a left renal pelvic tumor and was given two cycles of adjuvant chemotherapy (methotrexate, epirubicin and cisplatin). Echocardiogram showed an 8-mm sized mass extending from the right atrium into the right ventricle. On computed tomography, multiple lung tumors, as well as the right atrial and ventricular mass, were seen. The patient died of acute heart failure caused by right ventricular outflow obstruction. On autopsy, a right atrial and ventricular metastasis of the initial transitional cell carcinoma was found. The patient's cause of death was acute heart failure as a result of cardiac metastasis of his initial renal pelvic carcinoma. 相似文献
52.
Holger F. Boehm Felix Eckstein Caecilia Wunderer Volker Kuhn Eva-Maria Lochmueller Karin Schreiber Dirk Mueller Ernst J. Rummeny Thomas M. Link 《Journal of clinical densitometry》2005,8(4):488-494
We tested the hypothesis that bone mineral density (BMD) and bone mineral content (BMC) in proximal human femur specimens in the upper neck region of interest (ROI) and femoral neck axis length (FNAL) provide a significantly better prediction of femoral bone strength than standard ROIs in vitro. BMD and BMC were measured in 110 proximal femur specimens using a standard dual-energy X-ray absorptiometry (DXA) scanner. The analysis included a new ROI in the upper neck as well as the standard ROIs. FNAL was obtained from the scan images. The specimens' failure-load was measured in a mechanical loading device, simulating a fall on the greater trochanter. For the standard ROIs, correlations between failure-load and BMD ranged from R2 = 0.64 (shaft ROI) to R2 = 0.70, p < 0.001 (femoral neck). Prediction of strength by BMD did not significantly differ from those of BMC (R2 ranging from 0.65 to 0.75, p < 0.001). In the upper neck ROI, for both BMD and BMC correlations with failure-load were higher (R2 = 0.76 and 0.81, respectively; p < 0.001). A lower, yet still significant, correlation was found between FNAL and bone strength (R2 = 0.23, p < 0.001). Normalization of failure-load with respect to FNAL did not significantly increase the correlations with densitometric measures. This study provides in vitro evidence indicating that among the ROIs of the proximal femur the newly defined upper neck ROI provides the best prediction of bone strength. Only a weak association was observed between failure load and FNAL. 相似文献
53.
Long Fibre Growth by Axons of Embryonic Mouse Hippocampal Neurons Microtransplanted into the Adult Rat Fimbria 总被引:1,自引:0,他引:1
We have described a method for the microtransplantation of a suspension of a few thousand cells from mid to late embryonic mouse hippocampi into the fimbria of immunosuppressed adult rat hosts. There was close graft-to-host contact, across a non-scarred interface. The transplanted cells included CA3 type pyramids, and were enclosed within the host myelinated fibre tract, whose glial framework was largely undisturbed. Immunohistochemistry of two species-specific markers (M6 and Thy-1.2) showed that the donor mouse neurons grew fine (<0.5 μm diameter) axons which extended singly or in fascicles through the rat host fimbria for a maximum distance of at least 10 mm. The donor axons were intimately integrated among and closely aligned to the host tract axons and to the interfascicular glial rows of the host tract. The axons travelled (i) laterally through the ipsilateral fimbria, (ii) medially across the midline in the ventral hippocampal commissure to reach the contralateral fimbria and alveus, and (iii) rostro-medially to the septum. On approaching the terminal fields appropriate to hippocampal CA3 pyramidal cell axons, the transplant axons gave rise to fine preterminal branches which were continuous with a reticular or amorphous immunoreactivity in the stratum oriens and stratum pyramidale of the ipsilateral hippocampus, and in the lateral and triangular septal nuclei. The donor axons extended along the host fimbria at a rate of ∼ 1 mm per day, reaching their terminal field destinations by ∼1–2 weeks. At 7 weeks the projections were maintained, but with little further extension. These observations indicate that the microenvironment of myelinated adult fibre tracts is permissive for an abundant and rapid growth of axons from transplanted embryonic cell suspensions. These axons can leave host tracts to invade appropriate terminal fields. 相似文献
54.
Ureteropelvic junction obstruction was noted in a newborn male infant with acro-pectoro-renal field defect. To our knowledge, this association has not previously been reported. Ultrasonography of the urinary tract should be performed on all children with aplasia of the pectoralis major muscle. 相似文献
55.
本文报道1988年6月~11月,单独应用上海交通大学电力工程系研制的JT—ESWL—Ⅱ型体外震波碎石机,治疗尿路结石506例,其中肾结石304例(双侧12例)输尿管结石199例(双侧5例),膀胱结石3例。冲击能量15~40焦耳,每次治疗冲击波次数为400~2800次。本组无开放手术、无肾脏丧失、无死亡。效果满意者96.44%。其并发症主要有血尿、结石串。作者认为单用ESWL治疗小于3Cm的尿路结石安全可靠、无严重并发症。文中对单用体外震波碎石(ESWL)治疗尿路结石病例选择,如何减少并发症,提高治疗效果进行了讨论。 相似文献
56.
尿路复合性恶性肿瘤(附21例报告) 总被引:4,自引:0,他引:4
报告21例尿路复合性恶性肿瘤,位于肾盂2例,膀胱19例。主要临床表现为血尿,绝大多数病人伴有尿路刺激症状。低分化的移行细胞癌(TCC)与继发性复合肿瘤有密切关系。21例中1例为TCC复合肉瘤,11例为TCC复合鳞癌,7例为TCC复合腺癌,2例为腺癌复合鳞癌。本组2例肾盂肿瘤分别行肾输尿管全长加膀胱袖口状切除术和肾部分切除术,术后存活6个月和1年;膀胱肿瘤14例行膀胱部分切除术,已生存3年4例,1年2例,未满1年2例,3例1~2年内死亡,失访3例;2例根治性膀胱全切术已生存5年和3年以上;3例行TURBt,已生存3年1例,15年1例,未满1年1例。对尿路复合性恶性肿瘤的组织学、临床和病理特征进行了讨论。 相似文献
57.
对我院14年来2322例直接胆管造影所发现的27例AJPBD进行研究,27例中胆总管囊肿8例,胆石症9例,慢性胰腺炎4例,胆管炎3例,胆囊癌2例,胰体癌1例。临床表现为上腹痛(92.6%),黄疸(70.4%),发热(48.1%)或Charcot三联症(44.4%)。发病年龄3~60岁(36.9士17.8)。共同管长15~44mm(20.2士5.9)。据胆、胰管汇合形式作者将AJPBD分为三型。值得注意的是本组3例复杂型患病年龄均<15岁。本组以胆、肠内引流手术效果满意。AJPBD与胆、胰疾病发生、发展密切相关,作者建议用“共同管综合征”来表述这一复杂病理现象。 相似文献
58.
D. A. Haskins J. S. Jahr M.D. M. Texidor U. Ramadhyani 《Acta anaesthesiologica Scandinavica》1992,36(6):513-515
Omeprazole is a substituted benzimidazole that causes dose-dependent intracellular inhibition of gastric acid secretion in humans. This double-blind study examined the effect of omeprazole in decreasing gastric acidity and gastric residual volume in outpatient adults. Unpremedicated outpatients, ASA I-III, 18 years or older (n = 17), were randomly assigned to receive omeprazole 80 mg, or placebo by mouth the night before scheduled elective outpatient surgery. The patients were fasted for 8 h prior to surgery. After the patient was anesthetized, an orogastric tube was inserted with proper placement verified by auscultation for gastric sounds. Gastric residual contents were withdrawn into a Luken's trap, and pH was then determined and gastric volume indexed to weight (ml.kg-1). Data were analyzed by a t-test, with P less than 0.05 considered statistically significant. Patient characteristics of both groups were similar. There was a statistically significant difference between the two groups for pH (P = 0.02), but not between the two groups for gastric volume indexed to weight (P = 0.07). 相似文献
59.
目的总结瓣膜置换患者行胆道手术的术前用药方法。方法对38例瓣膜置换后在服用华法令过程中因胆道疾病需行择期手术治疗的患者随机分为2组,肝功能正常组(A组)23例、肝功能不正常组(B组)15例均于术前3d停服华法令,B组术前12h肌注VitK110mg。术前无应用华法令历史的患者115例做为对照组。结果38例患者停药2d后A组血浆凝血酶原时间与对照组差异无显著意义,B组于术前12h肌注VitK110mg后,血浆凝血酶原时间与对照组相比差异也无显著性意义。结论瓣膜置换患者在抗凝期间行胆道手术,只要准备充分,围手术期是安全的。 相似文献
60.
深部病原真菌菌种4453株分析 总被引:1,自引:0,他引:1
目的 分析深部病原真菌菌种分布。方法 收集1991-2003年我院门诊及住院病人6533例,对其标本按真菌培养分离鉴定步骤进行鉴定。结果 分离出白念珠菌3555株(85.44%),克柔念珠菌309株(7.43%),高里念珠菌239株(5.74%);呼吸系统分离出真菌3004株(68.35%);消化系统真菌1291株(29.37%);泌尿生殖系统87株(1.98%);神经系统8株(0.18%);血液5株(0.11%)。结论 念珠菌属尤其白念珠菌是我院近13年间系统性真菌感染的重要致病菌;合理应用抗生素及早期诊断尤为重要。 相似文献