Involvement of the Right Atrium by Malignant Lymphoma as a Cause of Right Cardiac Failure: Report of a Case

(Received for publication on Oct. 26, 1998; accepted on Nov. 11, 1999)     

RANDOM SYSTEMS OF HARD PARTICLES:MODELS AND STATISTICS

1　Ｉｎｔｒｏｄｕｃｔｉｏｎ　　Ｉｎｍａｎｙｓｉｔｕａｔｉｏｎｓ ,ｅｎｇｉｎｅｅｒｓａｎｄｓｃｉｅｎｔｉｓｔｓａｒｅｃｏｎ ｆｒｏｎｔｅｄｗｉｔｈｉｒｒｅｇｕｌａｒｓｐａｔｉａｌｓｔｒｕｃｔｕｒｅｓｗｈｉｃｈｃａｎｂｅｉｎ ｔｅｒｐｒｅｔｅｄａｎｄｍｏｄｅｌ     

连银汤提取工艺的正交实验研究

目的　确定从连银汤中提取绿原酸的最佳工艺条件。方法　采用正交实验的方法 ,以绿原酸提取率和得膏率为指标 ,来考查浸泡时间、加水量和煎煮时间对绿原酸提取效果的影响。结果　最佳提取条件为 :加 (12 +8)倍水 ,不浸泡 ,直接煎煮 (1+1) h。结论　该最佳工艺是稳定可行的 ,可用于工业化生产     

三种提取工艺对槐花颗粒剂芦丁含量的影响

目的　探讨槐花的提取工艺对槐花颗粒剂芦丁含量的影响。方法　采用水提取法、水提醇沉法和醇提取法分别提取槐花后制备颗粒剂 ,然后用紫外分光光度法测定其芦丁的含量。结果　水提取法和醇提取法制备的槐花颗粒剂芦丁含量相接近 ,水提醇沉法最低。结论　水提取法制备槐花颗粒剂 ,方法合理可行 ,而水提醇沉法不可取     

Effect of peripheral nerve lesion and lumbar sympathectomy on peptide regulation in dorsal root ganglia in the NGF-overexpressing mouse

Galanin is a peptide normally expressed at low levels both in sensory and in sympathetic neurons. It is strongly upregulated after peripheral nerve lesions, and it has been proposed that nerve growth factor (NGF) plays a role in this regulation. In the present study the effect of both sciatic nerve transection and lumbar sympathectomy on galanin in lumbar dorsal root ganglia (DRGs) was examined in mice overexpressing NGF (NGFOE) in the skin under the keratin promoter. The superior cervical ganglia (SCG) were also studied. In the DRG pericellular baskets containing tyrosine hydroxylase- (TH) and galanin-like immunoreactivity (LI) were found, mostly in the same fibers. Galanin-positive baskets were also found in the trigeminal ganglia. However, only single neuropeptide Y (NPY)-positive baskets were observed within the DRGs. No marked difference in number of galanin-positive neurons was seen between wild-type and NGFOE mice. After sciatic nerve transection galanin was upregulated in DRG neurons to about the same extent in NGFOE mice as in wild-type mice. Galanin-, but not TH-LIs decreased in the pericellular baskets. After lumbar sympathectomy both galanin- and TH-immunoreactive baskets disappeared, suggesting a sympathetic origin. In the SCG the very low galanin mRNA levels were strongly increased after lesion of the carotid nerves, both in wild-type and in NGFOE mice. However, whereas NPY mRNA levels decreased in the SCG after axotomy in the wild-type mice, there was a distinct increase in the NGFOE mice. Our results show that high NGF levels in skin induce formation of pericellular baskets in DRGs expressing galanin- and TH-LI and that galanin in these baskets is strongly influenced by peripheral axotomy. However, overexpression of NGF did not markedly influence galanin expression in DRG neurons, neither normally nor after nerve lesions. Finally, expression of NPY in sympathetic ganglia is differently regulated in NGFOE compared to wild-type mice.     

博落回药材的提取工艺研究

目的：研究博落回药材的提取工艺。方法：采用正交试验法，以白屈菜红碱得率及固形物为指标，考察乙醇浓度（A）、提取温度（B）、pH值（C）三个因素对博落回提取工艺的影响。结果：优化的博落回提取工艺为A2B1C2，即取博落回药材以80%乙醇、调节pH=5.0、60℃温浸提取。结论：本研究确定的最佳工艺可行。     

髋部减压术配合中药治疗股骨头缺血性坏死52例

目的：观察髋部减压术配合中药治疗股骨头缺血性坏死的临床疗效。方法：52例患者均采用髋部减压，即股骨头髓芯减压和髋关节腔内减压（双减压）术，并配合中药三期辨证治疗。结果：52例患者均获得随访，随访时间12个月～30个月，其中优39例，良10例，差3例，优良率为94．2％。结论：采用股骨头髓芯减压及髋关节腔内减压（即双减压）术，同时结合中药治疗早期股骨头缺血性坏死有显著疗效，是一种良好的治疗方法。     

迷走神经干刺激对左上肺静脉电传导特性及心房颤动诱发的影响

目的:研究迷走神经干刺激对左上肺静脉和左心房间的电传导以及心房颤动的影响。方法:35只新疆家养犬,苯巴比妥30 mg/kg诱导麻醉和50~100 mg维持麻醉。以S1S160 ms(1 000 bpm),1~8 V电压,刺激迷走神经干,以舒张期域值的2倍刺激电压,程序S1S1100 ms(600 bpm)30 s和60 s和S1S2300/200 ms起步,5 ms步长递减扫描刺激左心耳、左心房-肺静脉结合部、左上肺静脉远中近端,比较迷走神经刺激下各刺激部位的有效不应期(ERP)和心房颤动(AF)的诱发。结果:左上肺静脉的电生理传导特性为双向传导、双向频率依赖性递减传导、逆向传导减慢和局部延迟传导。迷走神经刺激达到最大效应(基础心率降低50%)的背景下左心耳、左心房-肺静脉结合部、左上肺静脉远中、近端的ERP由(106±18)、(111±15)、(113±17)和(112±17)ms缩短到(88±17)、(94±14)、(101±12)和(112±20)ms,各部位ERP的离散度由11.2%增加到21.3%;迷走神经干刺激最大效应下AF的诱发率由49.9%增加到70.6%,左心耳、左心房-肺静脉结合部、左上肺静脉远、中近端的AF诱发率在S1S1100 ms(600 bpm)刺激下分别为62.9%、97.9%、68.5%和69.2%,在S1S2刺激下分别为20.1%、43.3%、9.3%和9.7%。心房-肺静脉结合部为AF诱发率最高部位97.9%(S1S1100 ms刺激)和63.4%(S1S2刺激)。结论:新疆家犬左心房和左上肺静脉有其独到的电生理传导特性和房颤的诱发率,迷走神经干刺激能够显著改变这些电生理传导特性和增加AF的诱发率。     

医疗保险异地安置流程管理存在的问题与思考

医疗保险异地安置流程管理存在表格内容、报销手续混乱，报销范围、比例和周期不规范，缺乏有效的监管机制和人性化服务意识，管理成本较高等问题，通过建立全国统一的异地安置表格模式、报销流程以及基本医疗保险药品和诊疗目录，加强对经办机构有效；监控机制，探索医疗机构和异地经办机构之间有效的合作来解决当前问题。     

关节腔灌注骨肽加中药熏蒸治疗股骨头缺血性坏死14例

目的：观察关节腔灌注加中药熏蒸治疗股骨头缺血性坏死的疗效，力求保护修复坏死股骨头关节面，提高患者生活质量。方法：14例患者给予关节腔灌注骨肽加中药熏蒸治疗，7天为1个疗程，连续治疗3个疗程后进行评价。结果：治疗前、后患者疼痛指数、关节活动度评定得分间差别有显著性意义（P〈0．01）。结论：关节腔灌注骨肽加中药熏蒸治疗股骨头缺血性坏死能改善患者的关节功能，加快肌力恢复，缩短康复疗程，提高保守治疗效果及生存质量。