针药合用治疗周围性面瘫146例

针药合用治疗周围性面瘫１４６例安徽省颍上县人民医院（安徽２３６２００）黄子英１９７０～１９９５年，笔者采用针药合用治疗周围性面瘫１４６例，疗效满意，现总结如下。临床资料１４６例均属门诊患者，参照《针灸学》（上海针灸学院编．北京：人民卫生出版社，１９７...     

医学气象学与SARS流行的相关性研究

目的从医学气象学角度探讨SARS流行与气象因素的相关性。方法以SARS高发区广州、北京为例,通过网络、报刊等媒介获取两地在SARS流行前后的相关气象因子(日最高温度、日最低温度、相对湿度)及SARS疫情报告,运用EXCEL2000及相关矩阵法统计分析气象因子与SARS流行的关系,并从医学气象学角度对其相关性作出探讨。结果①SARS在12.8～23.5℃发病率最高,且与最高温度呈负相关。②SARS发病与最低温度呈负相关,高发前期有明显的降温过程。③广州的相对湿度较北京高,但与SARS的流行相关性不大。④2001年冬平均气温高于往年。结论①相对湿度较大有利于SARS的发生。②SARS发生于温热天气,气温波动有助于其流行。③气候异常变化是SARS发生的诱因。     

体温筛选寒热体鼠自然模型的可靠性及对子代的影响

目的:观察体温筛选寒热体鼠自然模型的可靠性及对子代的影响.方法:通过测定大鼠肛温将其分为"寒体""热体"组,测定血糖、尿儿茶酚胺含量,雌雄鼠交配,检测子代肛温、血糖、尿儿茶酚胺、胰岛素及丙二醛含量.结果:热体鼠血糖、尿儿茶酚胺含量均高于寒体鼠,热体组子代肛温、尿儿茶酚胺、血糖及丙二醛含量均高于寒体组.结论:体温筛选寒热体鼠自然模型可靠,寒热体鼠体温、血糖呈遗传态势,热体鼠氧化过激反应显著.     

10%盐水冰袋的研制及临床应用

目的　探讨有效实用的临床物理降温方法。方法　选内、外科发热病人及五官科术后病人 10 0例随机分为对照组和观察组各 5 0例 ,对照组采用传统的冰块冰袋 ,观察组用自行研制的 10 %盐水冰袋 (冰霜状 )进行物理降温。结果　 10 %盐水冰袋低温持续时间长 ,冰袋松软 ,接触体表充分 ,易于固定 ,病人自觉舒适 ,降温、止血、止痛效果明显优于传统的清水冰袋 (P <0 0 5 )。结论　 10 %盐水冰袋制作简单、操作方便 ,在临床、社区、家庭护理中可广泛推广使用。     

扩肛式智能正压回流洗肠装置的设计与研制

目的设计并研制了一种新型的扩肛式智能正压回流洗肠装置。方法详细介绍此装置的组成结构、各组成部分的功能及其工作原理。结果其临床应用在一定程度上可减少病人的痛苦，同时减少护理人员的劳动强度，对于卧床不起或术后不能活动、大便困难的病人能提供很好的帮助，对结肠炎、便秘、降温亦有很好的疗效。结论扩肛式智能正压回流洗肠装置具有实用、高效、方便等特点，适合推广应用。     

Experiences with a compound method for estimating the time since death.

The temperature-based nomogram method for estimation of the time period since death was used at the scene of death as the primary method within a compound method in 72 consecutive cases. The situation and cooling conditions inspected and evaluated by the forensic pathologist at the scene are described as far as necessary to enable handling of the method. A comparison of the estimated period since death with the period determined by the police investigations demonstrates the reliability of the method. There were no contradictions in any of the 60 cases between the period of death estimated by this method and that determined by the police investigations. The criminal investigations were effectively supported in the earliest stages in 11 cases despite the fact that the period estimated was of considerable duration.     

补肾活血法对子宫内膜异位症不孕患者基础体温的影响

目的:探讨补肾活血法对子宫内膜异位症不孕患者基础体温的影响。方法:将45例内异症不孕患者按2∶1随机分为中药治疗组和西药内美通对照组,经过6个月经周期的治疗后比较两组基础体温的变化。结果:治疗组在治疗前后黄体时间的高低温差呈增加趋势,体温上升时间及黄体期体温波动呈下降趋势;对照组在治疗前后黄体时间、高低温差、体温上升时间和黄体期体温波动无显著差异。结论:补肾活血法治疗内异症不孕,能影响基础体温,提示中药对卵巢功能有调整作用。     

呼出气温度对儿童哮喘气道炎症变化的预测意义

目的 探讨呼出气温度（EBT）对哮喘患儿气道炎症变化的预测意义。方法 选择门诊初诊时符合纳入标准的哮喘患儿60例作为哮喘组,另选60例健康儿童作为对照组,应用最新的三代产品（X-halo）检测EBT水平,记录儿童哮喘控制测试（C-ACT）评分,比较哮喘组和对照组EBT水平和C-ACT评分差异。1个月后复诊根据患儿C-ACT评分,将其分为良好控制组、部分控制组和未控制组,检测三组EBT和FeNO水平,比较三组EBT水平和C-ACT评分差异,分析EBT和FeNO相关性。追溯其初诊资料,比较初诊时三组EBT水平和C-ACT评分差异,最后比较复诊和初诊时三组EBT水平和C-ACT评分的差异。结果 初诊时,哮喘组EBT水平显著高于对照组（P < 0.05）,C-ACT评分显著低于对照组（P < 0.05）。复诊时,不同控制水平的三组EBT比较差异有统计学意义,即未控制组 > 部分控制组 > 良好控制组（P < 0.05）;三组C-ACT评分比较差异亦有统计学意义,即良好控制组 > 部分控制组 > 未控制组（P < 0.05）。三组初诊EBT水平和C-ACT评分的组间比较差异均无统计学意义（P > 0.05）。与初诊时比较,复诊时良好控制组EBT明显降低（P < 0.05）,部分控制组和未控制组均明显升高（P < 0.05）;良好控制组和部分控制组C-ACT评分均明显升高（P < 0.05）,未控制组明显降低（P < 0.05）。复诊时未控制组EBT和FeNO水平呈正相关（P < 0.05）。结论 EBT对儿童哮喘气道炎症的变化具有预测意义。     

Antiproliferative activity and standardization of Tecomella undulata bark extract on K562 cells

Ethnopharmacological relevance

The bark of Tecomella undulata is primarily used in the treatment of syphilis, painful swellings and cancer by traditional healers. Also, it is claimed to be useful in treating urinary discharges, enlargement of spleen, leucorrhoea, leukoderma, tumors, liver disorders, gonorrhea, gout and promotes wound healing in Indian traditional system of medicine.

Aim

To establish a scientific validation for the antitumor effects of Tecomella undulata bark and explore the mechanistic pathway in chronic myeloid leukemia cell line, K562. The study was further extended to standardize the extract using quercetin as biomarker.

Methods

Induction of apoptosis by chloroform extract of Tecomella undulata bark (CTUB) was determined by MTT, Annexin V and caspase activation assays. The cell cycle analysis was done by flow cytometer and nuclear staining by DAPI. The standardization of the extract was performed through reverse phase-HPLC method under PDA detection.

Result

Results clearly showed the induction of apoptosis by CTUB in K562 cells. The effect was found to be dose dependent, having IC₅₀ of 30 μg/ml with activation of FAS, FADD, caspase 8, caspase 3/7 and fragmentation of DNA. The bioactive CTUB was determined to possess 0.03% (w/w) of quercetin.

Conclusion

The investigation clearly demonstrated the potential antitumor effect of CTUB, thereby validating the traditional claim. Quercetin, known to have anticancer activity is being reported and quantified for the first time from the bark of Tecomella undulata.