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排序方式: 共有10000条查询结果,搜索用时 23 毫秒
201.
Anthony P. Khalifah Ramsey R. Hachem Murali M. Chakinala Roger D. Yusen Aviva Aloush G. Alexander Patterson Thalachallour Mohanakumar Elbert P. Trulock Michael J. Walter 《American journal of transplantation》2005,5(8):2022-2030
Bronchiolitis obliterans syndrome (BOS) is a major cause of lung allograft dysfunction. Although previous studies have identified mild to severe rejection (grade>or=A2) as a risk factor for BOS, the role of minimal rejection (grade A1) remains unclear. To determine if A1 rejection by itself is a risk factor for BOS, we performed a retrospective cohort study on 228 adult lung transplant recipients over a 7-year period. Cohorts were defined by their most severe rejection episode (none, A1 only, and >or=A2) and analyzed for the subsequent development and progression of BOS using univariate and multivariate time-dependent Cox regression analysis. In the univariate model, the occurrence of isolated minimal rejection was a risk factor for all stages of BOS. Similarly, multivariate models that included HLA mismatch, cytomegalovirus pneumonitis, community acquired viral infection, underlying disease and type of transplant demonstrated that A1 rejection was a distinct risk factor for BOS. Furthermore, the associated risk with A1 rejection was slightly greater than the risk from >or=A2 and treatment of A1 rejection decreased the risk for subsequent BOS stage 1. We conclude that minimal rejection is associated with an increased risk for BOS development and progression that is comparable to A2 rejection. 相似文献
202.
203.
Morris R.S.; Paulson R.J.; Sauer M.V.; Lobo R.A. 《Human reproduction (Oxford, England)》1995,10(4):811-814
Ovarian hyperstimulation syndrome (OHSS) is a serious complicationof gonadotrophin usage but it is difficult to accurately predictits occurrence. Previous investigators have identified the combinationof high oestradiol concentrations and oocyte number as beingpredictive in 80% of cases. In this study we sought to identifythe incidence of severe OHSS in patients with high oestradiolconcentrations and large numbers of oocytes and to evaluatethe importance of pregnancy in the development of OHSS. Between1990 and 1993, we studied 139 cycles using two assisted reproductivetechniques [oocyte donor, n =72; in-vitro fertilization (IVF),n = 67] in which either oestradiol (>4000 pg/ml), oocytenumber (>25), or both were elevated. OHSS was diagnosed bystandard criteria. There were no cases of severe OHSS in theoocyte donor group and six in the IVF group. Among 10 patientswith oestradiol concentration >6000 pg/ml and >30 oocytes,only one had OHSS (10%). The relative risk of OHSS with pregnancywas 12 (confidence interval 2.1866.14). We conclude thatthe risk of OHSS even at high levels of stimulation is lowerthan previously believed. Secondly, donors have a very low riskof OHSS, probably because of the absence of pregnancy. As such,cryopreservation of all oocytes in IVF cycles is a reasonablealternative to cycle cancellation or use of adjunctive medication. 相似文献
204.
感染日本血吸虫的家兔治疗前后肝纤维化动态观察 总被引:1,自引:1,他引:0
感染日本血吸虫的家兔治疗前后肝纤维化B超声像图模型、血清MAO水平及病理学结果表明,血吸虫引起的肝纤维化变化过程与血清MAO水平升降趋势趋向一致,均在18周达到高峰。解剖与病理学检查结果基本相符,血吸虫性肝纤维化形成后,只要及时给予杀虫治疗,肝纤维化部分可发生逆转。 相似文献
205.
运用文献计量分分析法对本刊1992-1995年16期所刊文章作了分析。结果:致突变的文章较多;每篇文章作者平均3.94人,大多集中在高等院校及科研机构,地区分布较广,高产作家尚少;平均引文8.22篇,引文以中、英文期刊为主;文献半衰期为中文4.16年,英文6.93年;有8种核心期刊;自引率较高。与创刊后的前12期(1989-1992)相比:一次性文献比重明显增加,致畸文章比重增加,高产作家相对增多,英文引文增加,英文半衰期缩短近二年半,提示刊物水平有提高趋势。 相似文献
206.
Clinical course and environmental factors were recorded in a prospective study of 276 unselected infants followed from birth to the age of 18 months. The study was performed with a questionnaire at the age of 6 and 12 months and a physical examination at 18 months. Fifty-nine (21%) of the children had greater than or equal to 2 episodes of wheezing before they were 18 months old. A total of 58 (21%) of the children belonged to the lowest social class V, 182 (66%) were daily exposed to passive tobacco smoking at home and/or in daycare, 164 (59%) were breastfed greater than or equal to 3 months, 192 (70%) were in daycare, 62 (22%) lived in flats and 167 (61%) were in daily contact with furred pets at home and/or in daycare. In social class V a preponderance of children were exposed to passive tobacco smoking, a majority were living in flats and a minority were breastfed greater than or equal to 3 months. Linear logistic regression analysis was used for the purpose of assessing the causal effect of environmental risk factors on the risk of recurrent episodes of wheezing before the age of 18 months. The study demonstrated that male sex and daily exposure to passive tobacco smoking were significant risk factors with estimated odds ratios 1.9 and 2.4, respectively. Maternal tobacco smoking seemed to be associated with the highest risk. There was a tendency--though not significant--indicating that breastfeeding greater than or equal to 3 months had a protective effect.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
207.
Graeme Penington Sally Warmington Susan Hull Nicholas Freijah 《ANZ journal of surgery》1992,62(10):774-779
Aspects of peri-operative management, amputation level and rehabilitation of the lower limb amputee are reported in the context of a review of a rehabilitation service for amputees which includes an integrated prosthetic service. Two hundred admissions were reviewed and some complex cases described. It is concluded that: a very close liaison between the surgeon and the rehabilitation team (ideally with pre-operative consultation) is in the patient's best interests; any person previously walking (or a potential walker) should be considered for a trial of prosthetic walking; an integrated prosthetic service enhances the efficiency of the rehabilitation service; and that modification of the current Artificial Limb Scheme to allow manufacture of first definitive limbs in prosthetic rehabilitation units would further enhance service to patients. 相似文献
208.
牙片中骨量与灰度的关系及灰阶的改进 总被引:2,自引:0,他引:2
本文对较小厚度范围内颌骨、金属铝在X片上的灰度水平与厚度变化关系进行了探讨,提出在数字减影牙片中以金属铝制成均匀楔形灰阶,代替传统金箔制成的台阶式灰阶. 相似文献
209.
210.