脑电生物反馈并红外偏振光穴位照射对注意缺陷多动障碍患儿脑功能的影响

目的探讨脑电生物反馈并红外偏振光穴位照射治疗对注意缺陷多动障碍（ADHD）患儿脑功能的影响。方法将66例ADHD患儿随机分为A、B两组,各33例。A组患儿给予脑电生物反馈治疗;B组患儿给予脑电生物反馈并红外偏振光穴位照射治疗,每次取百会等6个主穴,另取配穴2个。两组均治疗20次为1个疗程,共治疗2个疗程。治疗前、后及治疗后3个月评定韦氏儿童智力量表（C—WISC）、数字划消、Stroop测验、Cormers儿童行为量表。结果治疗后及治疗3个月后B组患儿韦氏c因子分分别为（109±14）分和（110±14）分,显著高于A组的（106±15）分和（103±12）分,差异有统计学意义（P〈0．05）;数字划消测评结果显示,治疗后两组患儿第一、二、三段净分较治疗前均显著提高,差异有统计学意义（P〈0．05）;Stroop测验结果显示,两组患儿治疗后词测验时间、色测验时间较治疗前均显著缩短,差异有统计学意义（P〈0．05）;Conner行为量表评分显示,治疗后及治疗后3个月B组患儿行为、学习、多动因子评分及多动指数较A组显著降低,治疗后B组患儿焦虑因子分也较A组显著降低,差异均有统计学意义（P〈0．05）。结论单纯脑电生物反馈治疗及脑电生物反馈并红外偏振光穴位照射治疗均能改善ADHD患儿的脑功能,但后者效果更佳,在改善患儿注意缺陷、减少多动冲动、缓解焦虑和改善学习状态等方面更为显著。     

Depth-dependent shear behavior of bovine articular cartilage: relationship to structure

The mechanical behavior of bovine articular cartilage in shear was measured and related to its structure through the depth of the tissue. To make these measurements, we designed an apparatus that could apply controlled shear displacement and measure the resulting shear force on cartilage specimens. Shear displacement and shear strain were obtained from confocal images of photobleached lines on fluorescently stained deformed samples. Depth-dependent collagen structure was obtained using compensated polarized light microscopy. Depth-dependent shear behavior and structure of samples from two animals were measured (group A and B). Both animals were 18–24 months old, which is the range in which they are expected reach skeletal maturity. In mature samples (group A), the stiffest region was located beneath the superficial zone, and the most compliant region was found in the radial zone. In contrast, in samples that were in the process of maturing (group B) the most compliant region was located in the superficial zone. Compensated polarized light microscopy suggested that the animal from which the group A samples were obtained was skeletally mature, whereas the animal yielding the group B samples was in the process of maturing. Compensated polarized light microscopy was an important adjunct to the mechanical shear behavior in that it provided a means to reconcile differences in observed shear behavior in mature and immature cartilage. Although samples were harvested from two animals, there were clear differences in structure and shear mechanical behavior. Differences in the depth-dependent shear strain were consistent with previous studies on mature and immature samples and, based on the structural variation between mature and immature articular cartilage, their mechanical behavior differences can be tenable. These results suggest that age, as well as species and anatomic location, need to be considered when reporting mechanical behavior results.     

自动夺获起搏器的临床应用

目的观察8例具有自动夺获功能的单心腔起搏器的各种参数特点及程控功能。方法8例患者,植入RegencySC+型VVI起搏器6例,RegencySR+型VVIR起搏器2例,随访1～18个月,检查动态心电图并通过程控观察起搏阈值、ER值及极化电位的变化。结果8例患者起搏功能良好,6例ER值及极化电位良好而打开自动夺获功能,起搏阈值稳定在0．9～1．5mV间,可见后备脉冲多为融合波触发。1例因ER值较低(1．8mV),另1例ER值偏低(3．3mV)且极化电位大于ER的60％,未能打开自动夺获功能。结论具有自动夺获功能的起搏器安全可靠,但有赖于良好的ER值、极化电位和感知安全度。ER值可能与心肌病变有关。调整ER感知灵敏度可能获得较好的ER信号及感知安全度。     

直线偏光红外线治疗仪在糖尿病合并周围神经病变中的疗效

目的:分析直线偏光红外线治疗仪在糖尿病合并周围神经病变中的疗效。方法:选取本院2018年4月~2019年4月收治的60例糖尿病合并周围神经病变患者开展对比研究,对照组患者采用常规治疗,试验组患者在常规治疗基础上采用直线偏光红外线治疗仪进行治疗,观察两组患者的治疗有效率以及治疗前后的症状积分和生活质量评分。结果:试验组患者的总治疗有效率为96.67%(29/30),显著高于对照组患者的76.67%(23/30),P<0.05。治疗后试验组患者的症状积分和生活质量评分分别为(2.32±0.80)和(78.91±6.44),均优于对照组患者的(4.07±1.42)和(66.69±6.59),P<0.05。结论:对于糖尿病合并周围神经病变患者采用直线偏光红外线治疗仪进行治疗可以有效改善患者的治疗效果。     

Probing tumor and peritumoral tissues in superficial and nodular basal cell carcinoma using polarized Raman microspectroscopy

Abstract:  Basal cell carcinoma (BCC) can sometimes lead, through a possible invasion of the dermis and the subcutaneous tissue, to serious local damage to the patient. Several histological types of BCC are reported, among them, the superficial, nodular and infiltrative forms. This study reports the use of polarized Raman microspectroscopy on the nodular and superficial types to discriminate between healthy epidermis and tumor, and between normal and peritumoral stroma. This technique probes additional information than conventional Raman spectroscopy because it is sensitive to the molecular ordering of tissue components. Depolarization ratios and hierarchical cluster analysis demonstrate that polarized Raman microspectroscopy can better identify the tumor and the peritumoral dermis than conventional Raman microspectroscopy, and hence gives potential complementary data about their molecular characteristics (molecular composition, secondary structure of proteins, intra- and/or inter-molecular bonding). Our findings also show that although superficial and nodular types of BCC were analysed, clear differences between the spectra of peritumoral and normal dermis could be detected.     

Dermoscopic features of digital mucous cysts: A study of 23 cases

Digital mucous cysts (DMC) are common benign myxoid cysts typically located on the fingers and toes. Recently, dermoscopic patterns of DMC were reported. However, only a small number of cases were described in the published work; therefore, information on this topic is scarce in the published work. We investigated dermoscopic patterns of histopathologically diagnosed DMC. In total, 23 cases were enrolled in this study. Polarized dermoscopy revealed vascular patterns in 13 cases (56.5%), with arborizing vascular patterns, dotted vessels, linear vessels and polymorphous vessels in eight (34.8%), three (13.0%), one (4.3%) and one (4.3%) case, respectively. Red‐purple lacunas, ulceration, nail dystrophy and white shiny structures were detected in five (21.7%), two (8.7%), seven (30.4%) and six cases (26.1%), respectively. We report the largest case series regarding dermoscopic features of DMC to date. Dermoscopy can be used as a helpful adjuvant and non‐invasive tool in the diagnosis of DMC.