子宫平滑肌瘤的MRI诊断

目的　探讨子宫平滑肌瘤的MRI表现及其诊断价值。方法　全部病例均行MRI及超声检查。结合手术病理结果回顾性分析 32例 ( 71个病灶 )子宫平滑肌瘤的MRI表现 ,并与超声检查相对比。结果　所有病灶MRI均表现为T1WI中等或略低信号 ;T2 WI低信号 ,退变型肌瘤夹杂有斑片状高信号 ,肿瘤边界清楚 ,瘤周大多可见包膜 ( 5 5 / 71)。对发现 <2cm的肿瘤、判断肿瘤变性及肿瘤的定位MRI均优于超声检查。结论　子宫平滑肌瘤MRI表现颇具特征性 ,较B超检出率更高 ,可获得更精确的资料 ,对制定治疗方案及随访观察肿瘤的变化具有较大的临床意义     

促性腺激素释放激素激动剂对子宫肌瘤病理及增殖细胞核抗原水平的影响

目的　通过测定应用促性腺激素释放激素激动剂 (GnRH A)后子宫肌瘤病理改变及增殖细胞核抗原水平变化 ,探讨GnRH A在治疗子宫肌瘤中的作用。　方法　子宫肌瘤术后标本 33例 ,术前应用GnRH A 18例为用药组 ,对照组 15例 ,常规病理检查 ,并用免疫组织化学 (ABC)方法检测增殖细胞核抗原 (PCNA)的含量。　结果　肌瘤组织变性率及免疫组织化学测定PCNA变化两组无明显差异 ,计算机图像分析表明用药后肌瘤细胞体积及间质有明显缩小 (P <0 0 5 )。　结论　本实验证实GnRH A治疗子宫肌瘤 ,肌瘤缩小与肌瘤细胞体积及间质缩小有关 ,停药后易复发 ,用于手术前治疗效果好     

Thoracoscopic enucleation of an esophageal leiomyoma with balloon dilator assistance

In consideration of the fact that procedures performed thoracoscopically cause less operative trauma and postoperative pain than those performed through an open thoracotomy, we believe that thoracoscopy should replace thoracotomy for the extraluminal transthoracic resection of benign esophageal tumors. We describe herein a new videothoracoscopic technique for performing the enucleation of an esophageal leiomyoma with balloon dilator assistance. The use of the balloon dilator facilitates separation of the tumor from both the mucosal and muscular layers of the esophagus, and may help to prevent perforation.     

口腔原虫感染与口腔疾病关系的研究

目的:探讨口腔原虫感染与口腔疾病的的关系。方法:从口腔疾病患者牙周组织或龈隙挑取渗出物,生理盐水涂片后镜检。结果:病人齿龈内阿米巴感染率为76％,齿龈内阿米巴与口腔毛滴虫混合感染率为6％,总计口腔原虫感染率为82％。疾病有龋齿、牙周炎、冠周炎及牙髓炎4组,4组疾病齿龈内阿米巴感染率分别为59.52％、85.29％、100％及88.24％,总计口腔原虫感染率分别为61.90％、97.06％、100％及94.12％。经统计学处理龋齿与后3组疾病之间有显著差异,而后3组疾病之间差别不显著。结论:3组疾病与齿龈内阿米巴及口腔原虫感染有密切关系。     

子宫动脉栓塞治疗子宫肌瘤疗效因素分析

目的 :探讨子宫动脉栓塞术 (uterinearteryembolizationUAE)对子宫肌瘤的治疗效果 ,并对影响疗效的因素进行分析。方法 :32例症状性子宫肌瘤患者 ,经超选择性插管双侧子宫动脉内注入PVA微粒栓塞治疗 ,术后 6个月随访复查 ,观察患者临床症状改善和子宫及肌瘤体积变化情况。结果 :UAE术后患者子宫出血症状改善最为明显 ,栓塞后 6个月肌瘤体积平均缩小 5 5 .6 %,肌壁间和黏膜下肌瘤的临床症状改善和体积缩小较浆膜下肌瘤明显。结论 :双侧子宫动脉栓塞治疗子宫肌瘤是一种安全有效的新方法 ;其疗效与栓塞术后肌瘤血管的重新构建 ,肌瘤类型 ,血供状态 ,子宫动脉单双侧栓塞等多种因素有关。     

Leiomyoma of the lesser omentum: Report of a case

The case of a 67-year-old Japanese woman with leiomyoma arising from the lesser omentum is reported herein. Although the patient had no abdominal symptoms, findings of a routine abdominal ultrasound examination suggested a mass between the stomach and the lateral segment of the liver. Subsequent magnetic resonance imaging (MRI) demonstrated a 6-cm well-encapsulated tumor in the lesser omentum, and this was confirmed intraoperatively. Resection of the tumor was performed without any other procedure and the histological diagnosis was confirmed as leiomyoma. The patient has been well for the 6 months since her operation. To our knowledge, this is the first report in the English literature of leiomyoma arising from the lesser omentum.     

子宫肌瘤组织中孕激素受体和表皮生长因子受体及细胞增殖相关抗原的表达

目的 :探讨孕激素 (P)和表皮生长因子 (EGF)对子宫肌瘤生长的影响。方法 :采用免疫组化SP法和计算机图象分析系统 ,定量分析子宫肌瘤患者的子宫肌瘤组织及子宫肌组织内孕激素受体 (PR)、表皮生长因子受体(EGFR)和细胞增殖相关抗原 (Ki- 6 7)的含量。结果 :(1)PR、EGFR和Ki- 6 7在子宫肌瘤组织中的表达明显高于子宫肌组织。 (2 )PR、EGFR在子宫肌瘤组织中的表达分泌期显著高于增生期 ,但在子宫肌组织中无变化 ;Ki- 6 7在两种组织中的表达分泌期明显高于增生期。 (3)子宫肌瘤组织中PR、EGFR与Ki - 6 7呈正相关。结论 :P和EGF在子宫肌瘤生长中起重要作用 ,EGF可能作为P介质起作用     

Myxoid leiomyoma of the vulva mimicking aggressive angiomyxoma

A case of vulvar leiomyoma with extensive myxoid change in a 40 year old female is described. The tumor had a unique connection with a non-degenerative leiomyoma that compressed the rectum and the bladder. Scattered smooth muscle cells in a loose myxoid stroma were immunoreactive for desmin. Fibroblast-like spindle cells were immunoreactive for vimentin but not for desmin. The initial, although incorrect, pathological diagnosis of the tumor was aggressive angiomyxoma based on the similarity in both clinical and pathological aspects with this more invasive tumor. Myxoid vulvar leiomyoma should also be differentiated from angio-myoflbroblastoma. The key to the differential diagnosis is the presence of interlacing smooth muscle cells and an awareness of tendency toward myxoid change in vulvar leiomyomas.     

手术前应用米非司酮治疗子宫肌瘤合并贫血的疗效观察

目的 :探讨米非司酮于手术前治疗子宫肌瘤合并贫血的疗效。方法 :将 34例子宫肌瘤合并贫血 ,拟行全子宫切除术的患者随机分为两组 ,观察组手术前每日口服米非司酮 12 .5 m g,连服 3个月后手术 ,对照组纠正贫血后择期手术 ,详细记录两组术中及术后各项指标并比较。结果 :观察组手术时间短 ,术中出血少 ,无一例输血 ,术后 2 4h血红蛋白及红细胞压积高于对照组 ,差异有显著性 ,术后住院日及术后病率均低于对照组 ,但差异无显著性。结论 :术前用米非司酮治疗子宫肌瘤合并贫血疗效显著 ,值得推广。