子宫肌瘤430例临床分析

目的:探讨子宫肌瘤治疗的方式选择.方法:对430例子宫肌瘤患者的症状进行分析,并对手术的412例手术方式进行讨论.结果:430例患者中,有临床症状者315例,占73.25%,无临床症状者115例,占26.75%.手术方式以全子宫切除为主,占84.30%.结论:子宫肌瘤患者中有一部分无临床症状,定期体检是早期发现和早期诊断的主要方法.手术方式需根据患者年龄,有无生育要求决定,尽量保留卵巢功能.     

米非司酮对离体子宫肌瘤细胞PR、PCNA、Bcl-2表达的影响

目的　探讨米非司酮治疗子宫肌瘤的可能机制。并证实孕激素在子宫肌瘤发病中的作用及子宫肌瘤与细胞调亡的关系。方法　体外原代培养子宫肌瘤细胞并传代后 ,加入不同浓度的米非司酮 ,继续培养 ,观察细胞增殖情况 ,并以免疫细胞化学方法检测孕激素受体 (PR)、增殖细胞核抗原 (PCNA)及凋亡抑制基因(Bcl- 2 )蛋白的表达。结果　成功的进行了子宫肌瘤细胞的原代培养 ,加入 1 0 - 4mol L米非司酮后 ,细胞增殖活动减少 ,PR、PCNA、Bcl- 2在子宫肌瘤细胞中的表达均明显下降 (P <0 0 5 ,P <0 0 5 ,P <0 0 1 )。结论　米非司酮治疗子宫肌瘤的机制可能是 :①米非司酮可直接抑制肌瘤细胞生长。②米非司酮通过抗孕激素作用抑制肌瘤细胞生长。③米非司酮可促进子宫肌瘤细胞调亡。反证了孕激素是子宫肌瘤的生长因素之一 ,亦说明子宫肌瘤与细胞调亡有关     

开平市三次人体重要寄生虫感染状况调查分析

目的分析开平市人体重要寄生虫病的流行情况,评估防治效果,为制定防治策略提供依据。方法收集开平市1989、1997、2002年三次寄生虫病调查所得数据进行分析,了解当地人体重要寄生虫病的流行态势。结果1989、1997、2002年三次调查,开平市检查人数依次为2029人、1030人、1516人;总感染率依次为50.02%、26.99%和11.21%;蛔虫感染率依次为34.84%、7.09%、4.68%;鞭虫感染率依次为13.26%、2.82%、0.59%;钩虫感染率依次为13.80%、0.68%、0.59%;12岁以下儿童蛲虫感染率依次为42.56%、37.90%、25.49%;华支睾吸虫感染率依次为1.68%、0.19%、4.42%。结论开平市蛔虫、鞭虫、钩虫感染率呈显著下降趋势,感染人数显著减少;蛲虫感染率稳步下降,但仍处于较高水平;华支睾吸虫感染率呈上升趋势。应加强蛲虫病和华支睾吸虫病的防治工作。     

超声引导下自凝刀射频治疗子宫肌瘤58例分析

目的:探讨自凝刀射频治疗子宫肌瘤的临床价值。方法:2004年2月~2005年6月选择自愿接受自凝刀射频治疗子宫肌瘤的患者58例,肌瘤68个,瘤体直径1.5~5.5 cm,在B超监视和引导下将自凝刀经阴道宫颈置入肌瘤进行射频治疗。结果:治疗后随访3个月58例、6个月50例(59个肌瘤),治疗有效率、治愈率分别为100%(58/58)、51.72%(30/58)。结论:自凝刀射频治疗子宫肌瘤是1种能保留子宫的微创技术,可重复治疗,疗效确切,操作简单,易推广应用。     

护理质量持续改进在子宫肌瘤护理中的应用简

目的 评价护理质量持续改进在子宫肌瘤护理中的效果.方法 选择2008年11月～2012年3月首都医科大学附属北京妇产医院收治的子宫肌瘤患者86例作为研究对象,将其随机分为观察组和对照组,每组各43例.对照组采用一般常规护理,观察组在常规护理基础上护理质量持续改进,比较两组临床疗效和生活质量,并对两组护理质量进行考核比较.结果 观察组痊愈16例,有效23例,总有效率为90.69％,对照组痊愈12例,有效22例,总有效率为79.07％,两组总有效率比较,差异有高度统计学意义（Ridit Z=36.954,P=0.000）;护理干预后,两组在生理、心理、社会、疾病、满意度及生活质量评分总分方面均有明显好转,差异有统计学意义（P＜0.05）,观察组好转程度优于对照组（P＜ 0.05或P＜ 0.01）;实施护理质量持续改进后,观察组在基础护理、护理安全、病房管理、消毒隔离、护理文书和急救物品方面改善均优于对照组,差异有统计学意义（P＜0.05）.结论 护理质量持续改进可以不断提高护理人员服务质量,提高患者生活质量,在子宫肌瘤护理中效果显著.     

肺良性转移性平滑肌瘤的临床病理研究及文献回顾

目的:研究发生于肺的良性转移性平滑肌瘤(BML)的临床病理特点。方法:收集本病1例,分析研究其临床表现、影像学资料、大体形态、组织学形态及免疫组化结果并查阅对照相关文献。结果:本例BML为49岁女性患者,子宫平滑肌瘤术后15年发生肺转移,无全身其他部位转移。组织形态类似于子宫平滑肌瘤,细胞无异型,未找到核分裂象,免疫组化染色结果符合子宫原发。结论:BML是一种罕见的发生于有子宫平滑肌瘤手术史的女性,肺是主要转移部位,呈激素依赖性,定期全身体检是早期发现肿瘤转移的关键。     

Imaging benign gynaecological conditions

Radiology continues to play an essential role in the management of benign gynaecological conditions. Multiple imaging modalities are utilised to investigate benign conditions: ultrasound; computed tomography and magnetic resonance imaging. Each modality has a different role in diagnosis, treatment selection and follow-up. This review discusses the different imaging modalities and their recommended roles in the imaging benign gynaecological conditions. The imaging findings of common benign female pelvic pathology are discussed and illustrated.     

人类子宫肌瘤保宫治疗进展

子宫肌瘤是女性生殖器官最常见的良性肿瘤，现代妇女对保宫治疗需求不断增强，本文对近几年来子宫肌瘤治疗的进展进行综述。     

Intestinal parasitic infections in suburban government schools,Lak Hok subdistrict,Muang Pathum Thani,Thailand

ObjectiveTo provide baseline information of parasitic infections in 3 suburban government schools, Lakhok subdistrict of Muang Pathum Thani, Thailand.MethodsThis study was conducted between May-June 2010 using simple direct smear and modified formalin ether and from a population of 1 253 in 3 suburban government schools.ResultsTotal samples of 202 registered and participated. The average of prevalence of infection from 3 schools was 13.9%, there were 13.7%, 14.3% and 13.9% in N, S and R school, respectively with no significant difference between schools (P>0.05). The infection rates did not show significant difference between genders (P>0.05). The highest rate of infection was 20.4% in Pathom 2 (8 years) students and the lowest was 4% in Pathom 1 (7 years) with statistically difference between age groups (P<0.05). The highest prevalence of pathogenic protozoa was Giardia lamblia (G. lamblia) which was found in 50% of infected cases, followed by 25% of Entamoeba histolytica (E. histolytica) and Blastocystis hominis (B. hominis). The highest prevalence of non-pathogenic protozoa was Endolimax nana (E. nana) which was found in 88.9%, followed by 11.1% of Entamoeba coli (E. coli). Mixed infections between Blastocystis hominis (B. hominis) and Endolimax nana (E. nana) were reported at 7.1%. The only helminthic infection found in this study area was hookworm, found in 1 student (3.8%). The formalin ether concentration technique showed a higher efficacy of detection (78%-100%) than the simple direct smear method (0%-50%).ConclusionsSurveillance of Protozoan infections may need to be focused on suburban areas.