芬太尼和咪唑安定分别与异丙酚联合用药与胃镜检查

目的：讨论胃镜检查中更加舒适的一种镇静镇痛方法。方法：芬太尼-异丙酚为Ⅰ组,咪唑安定一异丙酚组为Ⅱ组。观察记录各组术中的反应、胃镜操作时间、麻醉药物起效时间、苏醒时间和清醒时间,检查前中后BP、HR和SpO2的变化,及术后问卷调查。结果：Ⅰ组药物的起效快,受检者苏醒及清醒时间短,术中不适反应少,与Ⅱ组比较有统计学意义（P〈0．01）。结论：镇静无痛苦胃镜检查中芬太尼一异丙酚联合用药更舒适。     

胃镜下重酒石酸去甲肾上腺素喷洒与注射治疗急性 非静脉曲张性上消化道出血的疗效比较

目的探讨和比较胃镜下重酒石酸去甲肾上腺素喷洒与注射治疗急性非静脉曲张性上消化道出血(ANVUGIB)的临床疗效。方法选取2015年12月-2017年11月该院收治的92例ANVUGIB患者作为临床研究对象,采用随机数字表法,将入选患者随机分为观察组47例和对照组45例。观察组患者给予胃镜下重酒石酸去甲肾上腺素注射的临床药物治疗,对照组患者则给予胃镜下重酒石酸去甲肾上腺素喷洒的临床药物治疗,并分别对两组患者的临床治疗情况、临床指标变化情况和不良反应发生情况进行比较和分析。结果与对照组患者相比,观察组患者临床治疗的显效率57.45%(27/47)和总有效率91.49%(43/47)均明显提高,而无效率8.51%(4/47)则明显降低,差异均有统计学意义(P 0.05);观察组患者止血成功率91.49%(43/47)明显提高,差异有统计学意义(P 0.05),同时再出血率6.38%(3/47)和急诊手术率2.13%(1/47)则均有所降低,但差异均无统计学意义(P0.05);观察组患者腹部不适、大便频繁、胀气和血压不稳等不良反应总发生率10.65%(5/47)明显降低,差异有统计学意义(P 0.05)。结论胃镜下重酒石酸去甲肾上腺素注射治疗ANVUGIB较喷洒给药疗效更为确切,且预后效果好,并发症少。     

双钳道胃镜在上消化道异物治疗中的应用

目的评价用双钳道胃镜治疗上消化道异物的疗效和安全性。方法回顾性分析近3年来用双钳道胃镜治疗126例上消化道异物的临床资料。结果126例上消化道异物取出123例，成功率97．61％（123／126），未发生严重并发症；操作时间一般为3-15min；取出异物中横径最宽的达4cm，最长为18cm。结论用双钳道胃镜治疗上消化道异物安全、快捷、成功率更高。     

心电监测下老年冠心病患者胃镜检查的安全性分析

目的通过观察老年患者胃镜检查时生命体征的变化,探讨老年冠心病患者胃镜检查的安全性。方法选择在我院接受胃镜检查的60岁以上老年患者60例,分为冠心病组（术前有轻度sT-T改变或有过心绞痛或陈旧性心肌梗死病史,无呼吸系统疾病）30例,对照组（无基础心脏疾病）30例,比较两组老年患者胃镜检查时的心率、血压、血氧饱和度（Sp02）以及心电图变化。结果两组患者心率胃镜术中与术前比较均升高（P〈0．05）,相对变化值两组间比较有统计学差异（P〈0．05）;两组患者收缩压和舒张压胃镜术中与术前相比均有升高（P〈0．05）,组间比较无统计学差异（P〉0．05）;冠心病组患者Sp02胃镜术中较术前出现下降（P〈0．05）,但与对照组比较无统计学差异。二组均出现心律失常,但无危险性心律失常;冠心病组中6例患者出现ST段改变,术后恢复正常。结论对于老年冠心病患者,在术前进行充分准备,必要时术中心电监测,胃镜检查是安全的。     

内镜面罩给氧在麻醉胃镜检查中的应用

目的探讨无痛胃镜检查中采用内镜面罩给氧技术的可行性和安全性，并与通过鼻塞管给氧法相比较。方法60例胃镜检查患者均分为两组．通过内镜面罩给氧者为试验组（T组），通过鼻塞管给氧者为对照组（C组）。全部病例先静脉推注拘橼酸势太尼0．05mg，于20～50s内静脉注入丙泊酚2．5mg／kg，待患者意识消失后开始检查。在检查过程中分别检测血氧饱和度、血压、心率及操作时间，并对两组进行对比。结果血氧饱和度在对照组麻醉诱导后至检查结束期间明显降低．与诱导前相比差异有统计学意义（P〈0．05）。但在操作时间、心率、血压（收缩压和舒张压）方面两组间差异无统计学意义（P〉0．05）。结论辅以内镜面罩给氧进行无痛胃镜检查在维持生命体征指标上优于鼻塞管给氧，使无痛胃镜检查更为安全。     

急诊胃镜诊治上消化道大出血126例分析

目的:探讨急诊胃镜诊断上消化道大出血的临床特点及止血治疗效果。方法:对126例上消化道大出血行急诊胃镜常规检查后,立即进行胃镜下止血治疗,按不同病因、病变部位,使用喷药、粘膜下注射、套扎、血管栓塞、硬化剂治疗不同止血治疗方法。结果:采用局部喷药45例,粘膜下注射及电灼电凝30例均止血,血管出血行注射止血26例,出血停止,其中2例5～7天后再次临床少量出血,用药物加强治疗后出血停止。食管胃静脉曲张25例行套扎、DTH栓塞及硬化剂治疗,出血停止24例。本组总有效止血率99.2％(125/126)。结论:急诊胃镜是检查上消化道大出血病因及止血治疗的重要方法,具有出血灶检出率高,止血治疗快速有效的特点,值得临床大力推广应用。     

Circulating vaspin and its relationship with insulin sensitivity,adiponectin and liver histology in subjects with non-alcoholic steatohepatitis

During the study period 1972-74 gastric ulcer was demonstrated by endoscopy in 114 patients, 54 of whom were included in the present study. Forty-two were excluded because of ulcer showing incipient healing, superficial erosions, manifest or suspected malignancy, or indication for surgery. Eighteen patients were not included because of advanced age, complicating diseases, or refusal to have further examinations. The study comprises a treatment phase and a follow-up phase. The treatment phase ran from the first endoscopic demonstration of gastric ulcer until complete healing. During this period the patient was treated with antacids and anticholinergics and, if required by his condition, admission to hospital. During the treatment phase, endoscopy was performed at intervals of from 3 to 6 weeks until healing. During the follow-up phase endoscopy was carried out in the event of dyspeptic complaints that might indicate recurrent ulcer. The healing and recurrence rates for various periods were calculated by the aid of the life-table method. After 1 mo. of treatment 13% of the aptients exhibited healing, after 2 mo. 29%, after 3 mo. 41%, and after 12 mo. 79%. In one month 9% of the primarily healed ulcers had recurred, in 2 mo. 15%, in 3 mo. 22%, and in 12 mo. 43%. The healing rate is appreciably lower than results reported in the literature, whereas the recurrence rate is in closer accordance with previous studies.     

Gastric cancer screening in 16 villages of Zhuanghe region: a mass screeningreport from a high risk area of stomach cancer in China

AIM To study the comprehensive prevention and treatment of gastric cancer among high-risk population inthe high risk areas.METHODS A gastrocarcinoma mass screening was performed in 16 villages of Zhuanghe region. About50 000 population were involved and 3033 cases aged above 35 suffering from gastric diseases, and/or hadfamily history of gastric cancer were screened. Clinical epidemiological investigation, double-contrast X-ray,serum pepsinogen monitor, gastroscopic biopsies and histopathologic examinations were adopted in thescreening.RESULTS The ratio of the examined patients with gastric disorder reached up to 82% and 32 patients withgastric cancer were detected (1.06%) and 18 cases were early gastric cancer (56.25%). Patients with gastriccancer were treated successively. Aside from gastric cancer, several gastric lesions were also detected, whichlaid a good foundation for further interventional treatment. It was also found in the examination that93.97% of the local residents were addicted to salted pork and more than 60% of the residents had Hpinfection.CONCLUSION Gastric diseases, Hp infection of gastric mucosa and eating salted pork are very common inZhuanghe region. These are very dangerous factors causing gastric cancer. It is feasible to quit eating saltedpork and eradicate Hp infection and cure precancerous diseases.     

利宁凝胶联合丙泊酚用于无痛流产术效果观察

目的观察利宁凝胶联合丙泊酚用于无痛流产术中的效果。方法将600例早孕妇女随机分为观察组和对照组各300例,观察组采用利宁凝胶宫颈表面麻醉联合丙泊酚静脉麻醉,对照组仅用丙泊酚静脉麻醉。观察两组宫颈松弛度、肢体或身体扭动、呻吟下腹痛、手术时间、麻醉用药量、出血量。结果观察组宫颈松弛度明显好于对照组,疼痛发生率及平均手术时间、平均出血量明显低于对照组,P<0.05或0.01。结论利宁凝胶联合丙泊酚应用于无痛流产麻醉镇痛效果好,且较为安全,值得临床借鉴。     

十年内镜检查分析

目的了解胃肠疾病构成,分析胃肠疾病的季节变化及其发病趋势．方法收集中山医院１９８６０１／１９９５１２十年内镜检查资料,应用ＥｐｉＩｎｆｏ统计程序在计算机上进行统计分析．结果①在接受内镜检查的３０４３９例次病例中,男１９８８３例次,占６５３％．女性１０５５６例次,占３４７％．平均年龄４４岁±１３岁．胃大部切除术后９６２例次,占３８％;因上消化道出血接受检查４１２１例次,占１３５％．②在排除胃大部切除术后病例中,消化性溃疡的检出率最高,为３６２％,恶性肿瘤７３２例,占２５％,其中８２２％的病例年龄在４５岁以上．③对不同月份溃疡病检出率比较显示,十二指肠溃疡病的检出率在８月份最低,为１３１％,明显低于其他各月份;胃溃疡及复合溃疡在各月份检出率变化不大．④对不同年份溃疡检出率变化趋势分析显示,十二指肠溃疡病的检出率有逐年上升趋势．结论溃疡病在内镜检查中仍是主要的发现,且十二指肠溃疡发病近年有增加的趋势．在４５岁以上的人群应警惕胃癌发病的可能．早期内镜检查,及时诊断治疗可减少溃疡并发症如穿孔的发生