Retroperitoneal ancient schwannoma: case report and analysis of clinico-radiological findings

Ancient schwannoma is a rare subtype of typical schwannoma, with histological predominance of degenerative findings. We report the second case of retroperitoneal ancient schwannoma (occurred in a 45-year-old female referred to our institution for an unremitting right lumbar pain) and pinpoint clinical, radiological, prognosis and therapeutic aspects of this tumor.     

45例恶性周围神经鞘膜瘤临床病理分析

目的 了解恶性周围神经鞘膜病（ＭＰＮＳＴ）的临床病理特点。方法 分析４５例ＭＰＮＳＴ的临床特点,光崆春病理组织学变化并采用免疫组化ＳＰ法研究其免疫表型的异质性。结果 （１）本级人列年龄２～６８岁,中位年龄４１岁,常发生在四肢、躯干及脊柱等中轴部位;临床上电子学常见的症状为肿块。（２）ＭＰＮＳＴ的形态学瘤谱范围广,包括棱形细胞、上皮样细胞、原始神经上皮分化区及异源性成分等。（３）免疫组化染色Ｓ０－１     

椎管内神经鞘瘤的低场强MRI征象分析

目的探讨低场强MR对椎管内神经鞘瘤的诊断价值。方法回顾性分析经手术、病理证实的椎管内神经鞘瘤13例，分析其MRI的表现特点。结果13例均位于髓外硬膜下，其中颈段和颈胸交界段各1例、胸段6例、腰段5例。MRI均能清晰显示椎管内神经鞘瘤的形态与信号特征，肿瘤平扫T1WI多表现为稍低信号，T2WI为高信号。增强后肿瘤实体部分明显强化，肿瘤与邻近脊髓及硬膜囊的关系更加清楚。结论低场强MRI对椎管内神经鞘瘤的定位及定性诊断具有重要价值。     

超声对颈部神经鞘瘤诊断及鉴别诊断的价值

目的 回顾分析21例颈部神经鞘瘤的超声表现，总结其声像图特征及鉴别诊断。方法 21例病人均经手术病理证实，常规进行二维超声检查，记录其大小，回声类型，边界，均匀度，后方回声等声像图表现，其中10例应用了彩色多普勒血流成像检测肿瘤的血供情况。结果 21例颈部神经鞘瘤均为单发，声像图以低回声多见，伴有退行性变者，可表现为囊实性混合回声，肿瘤边界清晰，内部回声多为不均匀成欠均匀，彩色多普勒显示其血供丰富。结论 二维超声结合彩色多普勒超声对于颈部神经鞘瘤的诊断具有很大帮助。     

经枕下-乙状窦后入路显微手术切除听神经瘤42例分析

目的:探讨经枕下-乙状窦后入路显微手术切除听神经瘤保留面神经功能的可能性和可行性。方法:对42例听神经瘤患者均采取经枕下-乙状窦后入路显微手术行肿瘤切除术。结果:肿瘤全切除34例,次全切除8例。面神经解剖保留33例,出院时面神经功能保留率为52.4%(HouseⅠ~Ⅱ级22例)。平均随访5年,其中29例恢复良好,10例恢复一般,3例恢复较差。结论:经枕下-乙状窦后入路显微外科手术治疗听神经瘤是安全有效的,有利于面神经功能的保留。     

Two cases of neurilemmoma in the nasal vestibule: A case report and literature review

Rationale:Neurilemmoma is a benign tumor derived from the Schwann cells of the nerve sheath. The highest incidence of neurilemmoma occurs in the head and neck region; however, the nose and paranasal sinuses are rarely involved. Less than 4% of these tumors involve the nasal cavity and paranasal sinuses. To date, only six cases of nasal vestibule neurilemmoma have been reported.Patient concerns:Two patients (a 32-year-old man and a 42-year-old woman) visited our clinic with complaint of a lump in the left nasal vestibule.Diagnosis:Histopathological examination and immunohistochemical staining confirmed a neurilemmoma.Interventions:The mass was completely removed via an intranasal approach.Outcomes and Lessons:Neurilemmoma is easy to overlook because it occurs rarely in the nasal vestibule, but neurilemmoma needs to be considered as a differential diagnosis.     

脊髓神经鞘瘤的临床诊治体会

目的 探讨脊髓神经鞘瘤的诊断及治疗方法。方法 对１２例脊髓神经鞘瘤患者进行脊髓造影或ＭＲＩ检查。１０例患者肿瘤全部切除,１例次全切除,１例部分切除。其中５例患者采用显微外科手术治疗。结果 肿瘤全部切除术后神经功能均有明显恢复,次全切除１例有好转,部分切除１例复发。结论 脊髓神经鞘瘤行手术全部切除是可行的。熟练的手术技巧及肿瘤全切是取得良好效果的关键。     

Schwannoma in the retroperitoneum

Schwannoma (neurilemmoma) is a peripheral nerve sheath tumor and commonly occurs singularly on the head, neck, and trunk. Giant schwannoma is rarely located on the retroperitoneum and pelvic cavity. The majority of symptoms caused by the tumor are due to the effect of its mass. Surgical resection is enough to treat the tumor. Schwannoma is reported usually as benign, and despite incomplete resection of the tumor, the risk of recurrence and metastasis is low. A schwannoma on the retroperitoneum that was preoperatively misdiagnosed as a malignant adnexal mass in a 60-year-old menopausal woman is presented, with a brief review of the literature.     

原发性眶神经鞘瘤——附4例报告

原发性眶神经鞘瘤罕见,约占眶肿瘤的1%～3%。自1981年以来,我们治疗3例良性和1例恶性眶神经鞘瘤。眶神经鞘瘤是有包膜的、非侵犯性病变,除了机械性压迫之外,对其它眶组织影响甚微。其最常见的临床特征是缓慢的、进行性的眼球突出,可达几个月至数年.完整的手术切除可以治愈。但是,恶性眶神经鞘瘤则预后不良。