Resection of a retroperitoneal schwannoma by a combined approach

BACKGROUND AND PURPOSE: We report a remarkable case of retroperitoneal schwannoma with significant spinal growth illustrating the effectiveness of a combined surgical approach. METHODS: A 41-year-old man presented with a long history of back pain and unexplained weight loss. An abdominal mass was found in the right upper quadrant. The CT-scan revealed a partially cystic lesion located in the right psoas muscle. Spinal extension was noticed through the L1-L2 neural foramen. MRI better showed the wide rostro-caudal extension in the spinal canal. RESULTS: Bilateral L1 and L2 laminectomy was performed to remove the spinal portion of the tumor. It was extradural but attached to the dura. The roots were not infiltrated. The retroperitoneal mass was removed by an anterior transperitoneal approach. The histological examination did not reveal criteria of malignancy. CONCLUSIONS: Retroperitoneal schwannomas are rare and their preoperative diagnosis remains difficult. In case of significant spinal growth, a combined surgical exposure should be preferred to allow total removal of the lesion and control of the neurological structures.     

Neurilemmoma of the Facial Nerve presenting as a Parotid Mass

A facial nerve neurilemmoma manifesting as a parotide mass is a occurrence. Symptoms are slowly progressive and diagnosis is often delayed. We present a case report of a facial neurilemmoma, which presented as a parotid mass.     

Benign plexiform (multinodular) schwannoma: a rare tumour unassociated with neurofibromatosis

In reviewing a large series of soft tissue tumours, seven cases of benign plexiform schwannoma have been retrieved. These were solitary lesions, not associated with von Recklinghausen's neurofibromatosis, which arose in the dermis or subcutaneous tissue, predominantly in young adults. None has recurred. While the schwannomatous nature of these rare lesions is readily appreciated, the frequent presence of nuclear pleomorphism and the plexiform growth pattern should not be regarded as having sinister prognostic significance.     

马尾神经鞘瘤16例MRI诊断分析

[目的] 评价MRI对马尾神经鞘瘤的诊断价值。[方法] 16例马尾神经鞘瘤均行1．5TMRI平扫及增强扫描，并经手术病理证实；回顾分析肿瘤的MRI平扫和增强后的形态及信号特点及受累马尾神经的形态及信号特点。[结果] 16例马尾神经鞘瘤中14例为单发，2例为多发；14例位于硬膜内，1例位于硬膜外，1例位于硬膜内外呈哑铃形。18个病灶信号在T1WI上等于或低于脊髓的信号，在T2WI上等于或高于脊髓的信号。9例有囊变，1例合并蛛网膜下腔出血，增强扫描除囊变部分无强化外，其余部分呈明显强化。冠状面图像上4例可见肿瘤一侧相伴行马尾神经；横断面T1WI增强扫描上13例可见肿瘤上、下方或侧方有明显增粗强化的马尾神经；1例马尾神经被肿瘤包绕。[结论] MRI显示马尾神经鞘瘤瘤体本身及其受累的马尾神经的形态及信号特点具有独特性。     

骶椎神经鞘瘤MRI征象与临床病理特征分析

目的探讨骶椎神经鞘瘤的侵犯特点与MRI表现特征。材料与方法观察26例骶椎神经鞘瘤的MRI表现,根据生长部位、侵犯范围及有无囊变、"足突边缘"征,进行分型、分组测量瘤体最大径。比较型间及组间瘤体最大径的差异。对照分析瘤实质T2WI信号、强化效应及HE染色组织学表现。结果 1型4例,2型5例,3型10例,4型7例。骶前软组织肿块出现率高于骶板后(χ2=13.066,P=0.011)。骶椎中线与中线旁骨质破坏各5例、14例。第3型瘤体最大径大于其他型(t=2.655,P=0.014)。8例巨大侵袭性骶椎神经鞘瘤(giant invasive sacral Schwannoma,GTSS)瘤体最大径超过18例非GISS(t=3.027,P=0.006)。"足突边缘"征阳性12例与阴性14例间瘤体最大径差异无显著性(t=1.896,P=0.07)。囊变组12例的瘤体最大径、病程均长于非囊变组14例(t=2.928,P=0.007;t=-2.187,P=0.039)。Ⅰ区呈T2WI稍高信号、明显强化,对应Atoni A区;Ⅱ区呈T2WI高信号、无强化或轻微强化,对应Atoni B区。结论骶椎神经鞘瘤具有偏心性破坏和骶前侵犯特性。T2WI上稍高信号与高信号及其差异性强化是该瘤的MRI表现特征。     

外周神经复发性神经鞘瘤的显微外科治疗

目的　探索复发性神经鞘瘤的显微手术方法并观察其疗效。方法　本组 2 1例均采用显微外科切除方法 ,以瘤体远、近端正常神经束为线索 ,用窄而锐利的刀片纵向锐性切割快速切除肿瘤。结果　 2例术后 2周内有手麻痛 ,很快恢复。无 1例产生新的神经损伤并发症。随访 10个月至 5年 ,无 1例复发。结论　采用显微外科方法可以快速、彻底地切除复发性神经鞘瘤 ,而且能很好地保存神经功能 ,并可使肿瘤不再复发。     

颈静脉孔区神经鞘瘤的CT和MRI诊断

目的：探讨CT和MRI对颈静脉孔区神经鞘瘤的诊断及鉴别诊断。方法：回顾性分析了10例颈静脉孔区神经鞘瘤的CT和MRI影像资料。CT检查6例,其中4例作增强扫描,MR检查10例,其中8例作增强扫描,结果：根据CT和MRI表现颈静脉孔神经鞘瘤分为A,B,C三型,A型4例,B型1例,C型5例。神经鞘瘤易发生囊变,注射造影剂后肿瘤不均匀强化。结论：CT与MRI相结合,能更全面地为临床提供诊断,鉴别诊断及治疗所需要的信息,为治疗方法的选择提供可靠的依据。     

舌下神经管解剖学与哑铃型舌下神经鞘瘤手术入路研究

目的探讨哑铃型舌下神经鞘瘤的手术入路.方法采用20例干性颅底和15例寰椎标本及15例头颈湿性标本,对舌下神经管及相关结构进行测量和CT薄层扫描,并在湿性标本上研究暴露舌下神经管全程和内外口的手术入路.结果舌下神经管位置深在,周围结构复杂,其暴露的主要骨性障碍有寰椎横突、颈静脉孔、颈静脉结节和枕髁;以髁管和颈静脉孔为解剖标志在枕髁上方打开舌下神经管,切除寰椎横突,扩大枕髁前外侧的暴露,可在硬膜外暴露舌下神经管全程和内外口;结合硬膜下入路,可一期切除哑铃型舌下神经鞘瘤.结论远外侧经寰椎横突-髁上入路可作为哑铃型舌下神经鞘瘤一期手术切除的入路选择.     

腰骶部长节段神经鞘瘤一例报道

文章报道1例较少见的腰骶部长节段神经鞘瘤.患者以下肢无力伴尿潴留为主要临床表现,术前腰椎MRI表现为不连续的强化,诊断为腰骶部髓外、硬脊膜内多发性神经鞘瘤.肿瘤经显微手术完整切除,肿瘤长约15 cm.术后患者恢复良好.结合文献,对该病例的相关问题进行探讨.     

Epibulbar schwannoma in a 12-year-old boy: A case report and review of literature

Schwannomas are benign, encapsulated, primary neurilemmal tumors composed of proliferating Schwann cells. Schwannomas are commonly seen in the orbit, but are rare on the epibulbar surface. Herein, we report a case of a 12-year-old boy who presented to us with a slow-growing painless subconjunctival mass in the left eye. There was no intraocular extension of the mass and intra-operatively, the mass could be clearly delineated and was excised off the underlying sclera. Histopathological examination of the mass showed typical features of schwannoma and immunohistochemistry helped to confirm the diagnosis. There was no recurrence of the lesion observed at follow-up 26 months after surgery. Here, we describe this uncommon tumor and review the available literature. Although rare, an epibulbar schwannoma should be considered in the differential diagnosis of an amelanotic, painless subconjunctival nodular mass. Excision of the lesion is the recommended treatment.