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11.
U. Irlenbusch 《Der Unfallchirurg》1997,100(8):675-677
Summary
Two patients with complete paralysis of the axillary nerve are reported on. One case is well documented. In both cases there
was very good functional adaptation, resulting from hypertrophy of the rotator cuff so that there was only a slight or no
loss of movement. The rotator cuff should therefore be exercised at an early stage when there is isolated axillary nerve damage.
The function of the supraspinous muscle is also discussed.
相似文献
12.
Willem E. Corver Gert Jan Fleuren Cees J. Cornelisse 《Journal of immunological methods》2002,260(1-2):97-107
Background: High concentrations of propidium iodide (PI), in combination with fluorescein isothiocyanate (FITC) and R-phycoerythrin (RPE) used for multiparameter DNA flow cytometry (FCM), cause spectral cross-talk into the green fluorescence channel (FL1). We have evaluated the use of post-acquisition software compensation (N-Color Compensation) in order to correct this spectral cross-talk caused by PI. Method: Cell mixtures were prepared consisting of keratin 8/18 FITC labeled, keratin 8/18 RPE labeled, and unlabeled MCF-7 breast carcinoma cells. DNA was stained with PI (100 μM). Post-acquisition software compensation was applied to correct the spectral cross-talk of PI fluorescence. Secondly, the distribution of the Ki-67 (FITC) protein during the cell cycle (PI) of SiHa cervical carcinoma cells (no software compensation) was compared to the Ki-67 expression pattern of SiHa cells, simultaneously stained for keratin 8 (RPE), after applying software compensation. Finally, software compensation was used to compare the relative levels of PCNA and p53 expression in two clinical ovarian cancer ascites specimens, stained for PCNA or p53 (FITC), keratin 8/18 (RPE), and DNA (PI), with a known p53 status (positive and negative, respectively). Results: The Ki-67 cell cycle-dependent pattern of a triply stained sample (Ki-67 (FITC), keratin 8 (RPE), and DNA (PI)) is restored after software compensation and the results are comparable to the Ki-67 distribution of a sample stained solely for Ki-67 and DNA. P53 expression could only be resolved after using software compensation in the p53 positive ovarian ascites (OA) sample. Conclusions: We conclude that software compensation is a robust and reliable post-acquisition method for the correction of RPE/PI spectral cross-talk, permitting better identification of weakly expressed proteins in heterogeneous clinical tumor samples stained for multiple cellular antigens and DNA using PI. 相似文献
13.
药物不良反应事件民事赔偿问题研究 总被引:3,自引:0,他引:3
在药物不良反应事件中,药品存在设计缺陷、制造缺陷或警示缺陷的,药品的生产者应当承担赔偿责任。医疗机构无视药物不良反应的警示说明导致不良反应发生的,应当承担医疗差错的赔偿责任。国家疏于药物监管导致不良反应发。生的,从法学理论上讲,也应当承担赔偿责任。 相似文献
14.
B. Bagolini M. R. Zanasi R. Bolzani 《Documenta ophthalmologica. Advances in ophthalmology》1986,62(4):309-324
Esotropic patients whose angle of strabismus has been corrected by prisms frequently increase their angle deviation to compensate for the prismatic correction. This sensorio-motorial reaction to prism correction has been given the name of anomalous movements (a.m.). Quantification of a.m. has been made according to the amount of prisms that an esotropic patient is capable of compensating for (progressive prism compensation test - p.p. test). Some esodeviation does not compensate for any prisms at all since a.m. have not yet developed. Other cases compensate for as much as 40 or 60 prism diopters and more of over-correction of the angle deviation and they therefore have powerful a.m. The interference of these innervational forces acting on the medial recti to corrective surgery has been studied in 126 operated esotropic patients. A significant decrease from the expected surgical result (p < 0.001) has been found in patients having powerful a.m., as can be judged by the p.p. test. It is believed that a.m. are an important drawback contributing to vitiate any formula on the amount of muscle surgery to be performed in patients having no possibilities of restoring normal binocular vision.Practical advice on how to eliminate this drawback and theoretical reasoning on the significance of a.m. are offered. 相似文献
15.
16.
Examined differences between compensation seeking (CS) veterans and noncompensation seeking (NCS) veterans on the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and other psychological measures in 142 combat veterans evaluated for posttraumatic stress disorder (PTSD) at an outpatient Veterans Affairs (VA) hospital PTSD clinic. Patients were grouped on the basis of their compensation seeking status, with 69% classified as CS for PTSD. The CS veterans achieved significantly more pathological scores across a wide range of psychological inventories and MMPI-2 validity indices, although they did not differ in frequency of PTSD diagnoses from NCS veterans. Implications of these findings are discussed, and clinicians are advised to be aware of the compensation seeking status of combat-veterans being evaluated for PTSD. 相似文献
17.
Over the past 100 years Drosophila has been developed into an outstanding model system for the study of evolutionary processes. A fascinating aspect of evolution
is the differentiation of sex chromosomes. Organisms with highly differentiated sex chromosomes, such as the mammalian X and
Y, must compensate for the imbalance in gene dosage that this creates. The need to adjust the expression of sex-linked genes
is a potent force driving the rise of regulatory mechanisms that act on an entire chromosome. This review will contrast the
process of dosage compensation in Drosophila with the divergent strategies adopted by other model organisms. While the machinery of sex chromosome compensation is different
in each instance, all share the ability to direct chromatin modifications to an entire chromosome. This review will also explore
the idea that chromosome-targeting systems are sometimes adapted for other purposes. This appears the likely source of a chromosome-wide
targeting system displayed by the Drosophila fourth chromosome. 相似文献
18.
The quantity and quality of published research in the field of Virology by different world regions was estimated in this study. Using the PubMed database, articles from journals included in the "Virology" category of the "Journal Citation Reports" database of the Institute for Scientific Information for the period 1995-2003 were retrieved. The world was divided into nine regions based on geographic, economic, and scientific criteria. Data on the country of origin of the research was available for 33,425 out of 33,712 articles (99.2% of all articles from the included journals). USA exceeds all other world regions in research production for the period studied (42% of total articles), with Western Europe ranking second (35.7%). The mean impact factor in articles published in Virology journals was highest for the USA (4.60), while it was 3.90 for Western Europe and 3.22 for the rest of the world (seven regions combined). USA and Canada ranked first in research productivity when both gross national income per capita (GNIPC) and population were taken into account. The results of this analysis show a distressing fact; the absolute and relative production of research in the field of Virology by the developing regions is very low, although viral diseases cause considerable morbidity and mortality in these areas. It is evident from this study that developing regions need more help from the developed regions to enhance research infrastructure. 相似文献
19.
Compensation of labyrinthine lesions: effects of trigeminal neurotomy on vestibular field potentials
The aim of the research was to analyse the vestibular nuclear activity before and after the section of the 5th cranial nerve in chronically hemilabyrinthectomized guinea pigs during the stage of compensation. The animals were hemilabyrinthectomized (chloroform and vaselin oil into the right middle ear) and upon compensation (24–45 days), field potentials were recorded from the vestibular nuclei of the intact side following electrical stimulation of the ipsilateral labyrinthine receptors. Then the left trigeminal trunk was sectioned ventrally through the foramen lacerum and ovale which are fused in the guinea pig and the vestibular field potentials were again recorded for a period of 120 min. Trigeminal neurotomy modified the vestibular field potentials determining an increment in amplitude of 30–50% of N1 and N2 waves, configuration and latency remained unaltered. The dependence of vestibular compensation on trigeminal afferents is discussed on the light of reported results. 相似文献
20.
Goto F Straka H Dieringer N 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2002,147(3):374-386
Postlesional reorganization of vestibular afferent and commissural inputs onto second-order vestibular neurons was studied
in the isolated brain after unilateral section of the N.VIII, of the ramus anterior (RA) of N.VIII, of the utricular (UT)
or of the anterior vertical and horizontal canal nerves in combination. RA nerve section eliminated the inputs from utricular,
anterior vertical and horizontal canal organs. In the first set of experiments we recorded field potentials on the operated
side of the vestibular nuclei 2 months after RA nerve section. These responses were evoked by electrical stimulation of the
RA nerve or of the posterior vertical canal nerve on the operated or on the intact side. The amplitudes of afferent field
potentials evoked by stimulation of the spared posterior vertical canal nerve were increased. The amplitudes of afferent field
potentials evoked by stimulation of the axotomized RA nerve remained unaltered. After N.VIII section the commissural, but
not the afferent, field potentials increased significantly on the operated side following stimulation of N.VIII on the intact
and on the operated side, respectively. After UT nerve section no change in commissural but an increase in the amplitude of
afferent field potentials from each of the three intact canal nerves was observed on the operated side. In the context of
earlier results these findings imply that second-order vestibular neurons, disfacilitated due to afferent nerve section, became
receptive to additional, excitatory synaptic inputs, preferentially from intact vestibular nerve afferent fibers. The reduced
excitation via afferent nerve inputs was thereby replaced by other afferent nerve inputs from spatially inadequate vestibular
end-organs. The synaptic terminals of inactivated afferent nerve fibers were maintained and not repressed. The process of
central reorganization after vestibular nerve lesion was activity related, the expansion of signals restricted to inputs from
intact fibers, its extent graded and its onset delayed with respect to the onset of corresponding spinal changes and to the
onset of postural recovery after the same type of nerve lesion. After the section of RA nerve or of an individual nerve branch
the labyrinthine end-organs remained intact and were not removed as after unilateral labyrinthectomy (UL). Peripheral reinnervation
of the end-organs was thus excluded after UL, but expected after one of the former types of lesion. Functional reinnervation
of the utricular macula was mirrored behaviorally by the reappearance of severe postural deficits following a second RA nerve
section. These lesion-induced postural deficits began to reappear if the repeated RA nerve section was delayed with respect
to the first by about 3 months. We therefore studied postlesional reorganization in the brainstem 3 months after the first
RA nerve section. Reinnervation of the utricular macula was accompanied by a rapid decline of the increased amplitudes of
afferent and commissural vestibular field potentials towards control values, suggesting the reversibility of the lesion-induced
central reorganization.
Electronic Publication 相似文献