全文获取类型
收费全文 | 1993篇 |
免费 | 97篇 |
国内免费 | 82篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 43篇 |
妇产科学 | 6篇 |
基础医学 | 194篇 |
口腔科学 | 2篇 |
临床医学 | 242篇 |
内科学 | 366篇 |
皮肤病学 | 4篇 |
神经病学 | 34篇 |
特种医学 | 207篇 |
外科学 | 466篇 |
综合类 | 229篇 |
预防医学 | 42篇 |
药学 | 239篇 |
中国医学 | 34篇 |
肿瘤学 | 63篇 |
出版年
2023年 | 30篇 |
2022年 | 72篇 |
2021年 | 80篇 |
2020年 | 76篇 |
2019年 | 61篇 |
2018年 | 38篇 |
2017年 | 59篇 |
2016年 | 55篇 |
2015年 | 47篇 |
2014年 | 120篇 |
2013年 | 121篇 |
2012年 | 101篇 |
2011年 | 103篇 |
2010年 | 93篇 |
2009年 | 79篇 |
2008年 | 95篇 |
2007年 | 99篇 |
2006年 | 88篇 |
2005年 | 72篇 |
2004年 | 70篇 |
2003年 | 65篇 |
2002年 | 53篇 |
2001年 | 52篇 |
2000年 | 29篇 |
1999年 | 34篇 |
1998年 | 61篇 |
1997年 | 36篇 |
1996年 | 32篇 |
1995年 | 33篇 |
1994年 | 27篇 |
1993年 | 19篇 |
1992年 | 24篇 |
1991年 | 9篇 |
1990年 | 21篇 |
1989年 | 11篇 |
1988年 | 14篇 |
1987年 | 14篇 |
1986年 | 14篇 |
1985年 | 13篇 |
1984年 | 9篇 |
1983年 | 6篇 |
1982年 | 11篇 |
1981年 | 3篇 |
1980年 | 7篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1976年 | 2篇 |
1972年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有2172条查询结果,搜索用时 46 毫秒
51.
Wenhua Chen Hongjian Shi Kai Wang Shaoqin Li Feng Tian Zhongzhi Jia 《Journal of vascular and interventional radiology : JVIR》2021,32(1):49-55
PurposeTo investigate the safety and effectiveness of primary conservative therapy for patients with symptomatic isolated mesenteric artery dissection (IMAD) with a severely compressed true lumen and/or a large dissecting aneurysm.Materials and MethodsA total of 35 consecutive patients (all men; median age, 53 y) with symptomatic IMAD with a severely compressed true lumen and/or a large dissecting aneurysm but without intestinal necrosis or arterial rupture who were treated with primary conservative therapy between November 2018 and February 2020 were assessed. A severely compressed true lumen was defined as luminal stenosis > 70%. A large dissecting aneurysm was defined as dissecting aneurysm diameter ≥ 1.5 times larger than the normal mesenteric artery diameter.ResultsThere was a strong positive relationship among abdominal pain, degree of luminal stenosis, and length of dissection (R = 0.811; P < .001). Conservative treatment was successful in all patients. Abdominal pain was eliminated within 4.7 d ± 4.8 (range, 2–31 d) in all patients, within 3.6 d ± 1.2 (range, 2–6) in the 31 patients with minor or moderate abdominal pain, and within 13.3 d ± 11.9 (range, 6–31 d) in the 4 patients with severe abdominal pain. Complete or partial remodeling of the mesenteric artery was achieved in 6 (17.1%) and 29 (82.9%) patients, respectively, during 8.6 mo ± 4.3 of follow-up.ConclusionsPrimary conservative therapy can be used safely and effectively in patients with symptomatic IMAD with a severely compressed true lumen and/or a large dissecting aneurysm but without intestinal necrosis or arterial rupture. 相似文献
52.
53.
54.
Hideaki Hozumi Ryota Hokari Motonori Shimizu Koji Maruta Kazuyuki Narimatsu Hirokazu Sato Shingo Sato Toshihide Ueda Masaaki Higashiyama Chikako Watanabe Shunsuke Komoto Kengo Tomita Atsushi Kawaguchi Shigeaki Nagao Soichiro Miura 《Digestive endoscopy》2014,26(4):594-598
Phlebosclerotic colitis is a rare and recently known disease entity and its etiology is still to be elucidated. Some phlebosclerotic colitis cases are difficult to distinguish from collagenous colitis because of the similarity of pathological findings. In all Japanese case reports of phlebosclerotic colitis in which an association with the use of Chinese herbal medicine is suspected, sansisi (gardenia fruit) was included, suggesting pathogenesis of this disease. We report a case of phlebosclerotic colitis that wasdifficult to be distinguished from collagenous colitis, and an association with the use of Chinese herbal medicine was suspected as the cause of the disease. 相似文献
55.
Kostas Fasoulas Athanasios Beltsis Taxiarchis Katsinelos Eleni Dimou Mary Arvaniti Anna Charsoula Victor Gourvas Stefanos Atmatzidis Grigoris Chatzimavroudis Panagiotis Katsinelos 《Saudi Journal Of Gastroenterology》2012,18(2):146-148
Mesenteric panniculitis (MP) is a rare inflammatory and fibrotic disease of the mesentery of unknown etiology. It has various clinical and radiological manifestations, posing a diagnostic challenge for clinicians. Its diagnosis is indicated via radiologic imaging and is usually confirmed via peritoneal biopsies. We describe a case of a patient with histopathologically proven MP, in which steroid dependence was successfully managed with colchicine. 相似文献
56.
BackgroundAbdominal Compartment Syndrome (ACS) is a pathological condition that results from an increase in pressure within the abdomen associated with organ failure. It can be acute or chronic, primary or secondary.ACS poses a serious diagnostic challenge for physicians as the clinical presentation is varied and can mimic other medical pathologies. To prevent a multi-organ failure and ultimately death due to this disease, the World Society of Abdominal Compartment Syndrome (WSACS) suggested clinical criteria and biology tests to facilitate an early diagnosis of acute ACS.Case presentationWe report a case of 61 year-old man diagnosed with chronic mesenteric ischemia that has been successfully treated by prosthetic bypass. The postoperative period was eventual, the patient presented complications corresponding essentially to a manifest acute ACS. The treatment consisted on abdominal decompression and resuscitation measures.ConclusionsAn early diagnosis of ACS disease for an appropriate therapeutic initiation is mandatory to prevent its complications and save the patient's life prognosis. 相似文献
57.
Agata Arazińska Michał Polguj Andrzej Wojciechowski Łukasz Trębiński Ludomir Stefańczyk 《Clinical anatomy (New York, N.Y.)》2016,29(8):1025-1030
Median arcuate ligament syndrome (MALS) is a pathologic entity that can affect the celiac axis. Due to the extensive collateral network of mesenteric circulation, stenosis of one mesenteric artery does not lead to significant symptoms. The purpose of this study was to describe multidetector computed tomography (MDCT) angiography findings of celiac artery entrapment by the median arcuate ligament and determine those patients with high risks of ischemic complications. From January 2012 to March 2016, 103 patients with celiac artery (CA) compression by median arcuate ligament were detected. In 23 patients collateral circulation was developed. In order to investigate the problem, we managed to estimate the correlation between range of stenosis of CA and presence of collateral circulation between the celiac artery (CA) and superior mesenteric artery (SMA). A statistically significant correlation was found between range of CA stenosis and collateral circulation presence (Spearman's correlation coefficient 0.339, P < 0.0001). In conclusions, based on our observations, we hypothesize that ischemia as a result of mesenteric vessel narrowing by the median arcuate ligament may occur more often than indicated by clinical symptoms and described in literature. Clin. Anat. 29:1025–1030, 2016. © 2016 Wiley Periodicals, Inc. 相似文献
58.
J. Björk 《Scandinavian journal of gastroenterology》2013,48(12):1230-1235
Background: The Swedish Polyposis Registry was set up in Sweden in the late 1950s to promote screening of familial adenomatous polyposis (FAP). The aim of this study was to examine the epidemiology of FAP in Sweden, including the influence of screening on morbidity and mortality in colorectal cancer (CRC). Methods: Four hundred and thirty-one patients (213 males and 218 females) with FAP from 145 families recorded by the Swedish Polyposis Registry were investigated. The effect of screening on morbidity and mortality in CRC was evaluated by comparing the 216 probands with the 215 call-up patients. Three different periods were studied: the pre-screening period (1912-1956), the first screening period (1957-1976), and the second screening period (1977-1996). Results: The mean annual incidence rates during the three periods were 0.2, 1.38, and 0.86 per million, respectively. The birth frequency was calculated to be 1 in 18,000 between 1947 and 1966, and the prevalence was 32 per million at the end of 1996. The proportion of new mutants among the FAP patients born between 1927 and 1966 was estimated to be 11%. The median age at diagnosis of probands was 39 (range, 11-71) years and did not change over time, although an increase was seen in the subgroup with CRC at diagnosis (P = 0.02). In the call-up group the median age at diagnosis was 22 (range, 3-65) years. Sixty-seven per cent of the probands and 3.3% of the call-up patients had CRC at diagnosis, and the corresponding mortality figures were 44% and 1.9%. The risk among probands of having CRC at diagnosis decreased from 81% to 49% (P = 0.0006). Female probands were diagnosed with symptoms (P = 0.03) and CRC (P = 0.04) earlier than male probands. Conclusions: A nationwide screening program facilitates detection and early diagnosis of FAP. A decrease in CRC morbidity among probands contributed to the improved prognosis. An earlier onset of symptoms and CRC in females indicate that the course of FAP is influenced by sex. 相似文献
59.
Muta T Okamura T Kawamoto M Ichimiya H Yamanaka M Wada Y Urata M Kayamori Y Hamasaki N Kato K Eto T Gondo H Shibuya T 《European journal of haematology》2005,75(2):167-170
A 38-year-old woman was admitted with superior mesenteric vein (SMV) thrombosis, which was refractory to anticoagulation therapy. The plasma antithrombin activity was decreased and hardly compensated by concentrated antithrombin preparation due to high consumption rate. However, successful anticoagulation was achieved by administration of direct thrombin inhibitor, argatroban. Family studies of antithrombin activity revealed that she had type I congenital antithrombin deficiency. A novel heterozygous mutation in the gene for antithrombin (single nucleotide T insertion at 7916 and 7917, Glu 272 to stop in exon 4) was identified. Argatroban administration would be effective in the treatment of congenital antithrombin deficiency with SMV thrombosis. 相似文献
60.
Mesenteric inflammatory veno-occlusive disorder: a rare entity mimicking inflammatory bowel disorder
Mesenteric inflammatory veno-occlusive disorder (MIVOD) is a rare variety of inflammatory bowel disease. In addition to the case presentation, pathogenesis, and conflicting clinical, endoscopic, and computed tomography findings, we present for the first time the angiographic findings that would provide important clues to distinguish MIVOD from the chronic idiopathic variety of inflammatory bowel disease and confirm the diagnosis of MIVOD. Final diagnosis is made on full-thickness biopsy. Although medical treatment of MIVOD is unsuccessful, surgical resection of the involved segment results in resolution of symptoms. 相似文献